公开(公告)号：EP1032441A1

公开(公告)日：2000-09-06

申请号：EP97949690.8

申请日：1997-11-26

申请人： E-Z-EM, INC.

发明人： ZIMMET, Arthur

IPC分类号： A61M5/168

CPC分类号： A61M5/16836 ,  A61M2005/1588

摘要： The technique for detecting extravasation during the injection of fluid into a patient involves the establishment of a baseline representing impedance at the zone of the injection prior to the injection starting. Extravasation is signaled when at least two characteristics appear. First is that the impedance varies from the baseline more than a predetermined amount in more than a predetermined number of discreet time slots called epochs herein. Second is that, the rate of change of the impedance, which is called the slop herein, is consistently greater than a predetermined amount.

摘要翻译： 在将流体注入患者体内期间检测外渗的技术涉及在注射开始之前建立表示注射区域阻抗的基线。 至少有两个特征出现时，外部信号会发出信号。 首先是阻抗在超过预定数量的本文称为时期的预定数量的离散时隙中从基线变化超过预定量。 其次，阻抗的变化率（在此称为斜率）一直大于预定量。

公开(公告)号：EP0494732B1

公开(公告)日：1995-05-10

申请号：EP92300035.0

申请日：1992-01-03

申请人： E-Z-EM, INC.

发明人： Hobbs, Eamonn ,  Appling, William M. ,  Hawkins, Irvin F.

IPC分类号： A61M25/00

CPC分类号： A61M25/0041

公开(公告)号：EP0489590A1

公开(公告)日：1992-06-10

申请号：EP91311322.1

申请日：1991-12-05

申请人： E-Z-EM, INC.

发明人： Phillips, David ,  Appling, William M.

IPC分类号： A61M25/00

CPC分类号： A61M27/002 ,  A61M25/007 ,  A61M2025/0037 ,  A61M2027/004 ,  A61M2202/0403 ,  A61M2205/32 ,  A61M2210/1057 ,  A61M2210/1075 ,  A61M2202/0007 ,  A61M2202/0014

摘要： A drainage system for draining bile comprises an elongate drainage catheter (12) with a distal segment (18) and a proximal segment (16). A first lumen (20) extends longitudinally through at least a portion of the distal catheter segment (18) and longitudinally through the entire length of the proximal catheter segment (16) and communicates with the exterior of the catheter through a plurality of openings (26) in the distal catheter segment (18). A second lumen (22) extends longitudinally solely through at least a portion of the proximal catheter segment (16) and communicates with the exterior of the catheter through a plurality of openings (24) formed in the proximal catheter segment (16). A drainage bag (14) is connected to the proximal ends of the two lumens and defines a bile reservoir (44). Two one-way reed valves (45,46) are provided in the drainage bag, one (45) being arranged to allow bile to enter into the reservoir (44) from the second lumen (22) and the other (46) being arranged to allow bile to exit from the reservoir (44) into the first lumen (20).

摘要翻译： 用于排出胆汁的排水系统包括具有远侧段（18）和近端段（16）的细长的排出导管（12）。 第一管腔（20）纵向延伸穿过远端导管段（18）的至少一部分并且纵向延伸穿过近端导管段（16）的整个长度并通过多个开口（26）与导管的外部连通 ）在远侧导管段（18）中。 第二内腔（22）纵向仅延伸穿过近侧导管段（16）的至少一部分，并且通过形成在近侧导管段（16）中的多个开口（24）与导管的外部连通。 排泄袋（14）连接到两个腔的近端并且限定胆汁储存器（44）。 两个单向簧片阀（45,46）设置在排水袋中，一个（45）被布置成允许胆汁从第二内腔（22）进入贮存器（44），另一个（46）被布置 以允许胆汁从储存器（44）离开到第一管腔（20）中。

公开(公告)号：EP1805683A2

公开(公告)日：2007-07-11

申请号：EP05813778.7

申请日：2005-10-27

申请人： E-Z-EM, Inc.

发明人： WILLIAMS, Robert, C., Jr. ,  HARTMAN, Steven ,  TENGCO, Tito ,  GODFREY, Clark ,  CROSS-HANSEN, Alan

IPC分类号： G06F19/00 ,  A61B5/00

CPC分类号： G16H40/63 ,  A61B5/053 ,  A61B6/481 ,  A61M5/007 ,  G06F19/00

摘要： The present invention comprises devices, systems, methods, and computer program products for managing data related to the dispensing of contrast media as part of a medical procedure. The device and system provide a controller that is capable of communicating with a dispensing device so as to extract, arrange, process, and present a data set (e.g., a usage data set) from the dispensing device to a user such that the user may selectively monitor statistics related to the administration of contrast media, saline, or other consumables used during one or more dispensing operations. The method and computer program product for managing data related to the dispensing of contrast media may further allow for extraction, arrangement, processing, and presentation of the data set via the controller, via a user interface that is operably engaged with the dispensing device and/or via a computer network that may be in communication with the dispensing device.

公开(公告)号：EP1636092A1

公开(公告)日：2006-03-22

申请号：EP04754413.5

申请日：2004-06-04

申请人： E-Z-EM, Inc.

发明人： HARTMAN, Steven ,  CROSS-HANSEN, Alan ,  GODFREY, Clark ,  WILLIAMS, Robert, C.

IPC分类号： B65B1/04

CPC分类号： B65B3/003 ,  A61M5/1782

摘要： The present invention is directed to a syringe filling station that can fill a syringe with a specified volume of fluid. In one embodiment, the syringe filling station comprises a reservoir attachment, a fluid delivery system, a syringe retaining guide, and a pump to move fluid from a reservoir to a syringe. The fluid delivery system may comprise a sterile consumable cartridge that is insertable into the filling station and defines a fluid pathway from a reservoir to a syringe. The syringe filling station may also include a user interface. An operator can input commands into the user interface to specify the amount of fluid to dispense into the syringe. The user interface may be connected to a processor that controls the rate of pumping and thereby can fill a syringe with a desired amount of fluid. The filling station may also include sensors that detect air in the tubing, depletion of the reservoir, among other things.

摘要翻译： 本发明涉及一种注射器填充站，其可以用特定量的流体填充注射器。 在一个实施例中，注射器加注站包括储存器附件，流体输送系统，注射器保持导向器以及将流体从储存器移动到注射器的泵。 流体输送系统可以包括可插入填充站并限定从储存器到注射器的流体路径的无菌可消耗筒。 注射器加注站还可以包括用户界面。 操作员可以将命令输入到用户界面中以指定分配到注射器中的流体的量。 用户界面可以连接到控制泵送速率的处理器，并且由此可以向注射器填充期望量的流体。 加油站还可能包括检测管道中的空气，储油层枯竭等的传感器。

公开(公告)号：EP1614194A2

公开(公告)日：2006-01-11

申请号：EP04757691.3

申请日：2004-03-19

申请人： E-Z-EM, Inc.

发明人： WILLIAMS, Robert, C., Jr. ,  SCHALLER, Ronald ,  HARTMAN, Steven

IPC分类号： H01R11/00

CPC分类号： H01R13/58 ,  H01R11/18 ,  H01R2201/12

摘要： The present invention relates to an electrical connector apparatus, system and method for use with medical devices. In an alternative embodiment, the apparatus of the present invention comprises a first component comprising a first electrical connector adapted to electrically couple with a medical device, and a second component for establishing a connection with an electrical circuit, preferably a microprocessor. The device of the present invention is especially suited for use with medical devices useful in detecting extravasation in an individual undergoing a fluid injection procedure, because it allows for patient mobility, ease of connection and disconnection and more efficient use of medical equipment such as CT scanning equipment.

公开(公告)号：EP0733380A1

公开(公告)日：1996-09-25

申请号：EP96104104.3

申请日：1996-03-15

申请人： E-Z-EM, INC.

发明人： Appling, William M. ,  Greenizen, Kurt E. ,  Recinella, Daniel K.

IPC分类号： A61M39/10

CPC分类号： A61M39/10 ,  A61M2039/1033 ,  A61M2039/1077 ,  Y10S604/905

摘要： A luer-type adapter has a dual instead of a single set of engaging screw threads. A proximal and a distal screw thread on the hub engage proximal and distal screw threads on the collar of the connector to provide at least twice the engaging or sealing force between the tapered surfaces of the stem and hub which are forced together by rotating the collar relative to the hub to engage the two sets of threads. The diameters of the engaging distal screw threads have to be sufficiently great so that the proximal screw thread on the hub can pass under the distal screw thread on the collar in order to effect proximal as well as distal engagement. An O-ring mounted on an untapered distal segment of the stem engages an untapered inner hub surface to provide additional sealing force which is particularly useful where gas is being provided through the adapter.

摘要翻译： 路厄型适配器具有双重性，而不是单组接合螺纹。 轮毂上的近端和远端螺纹接合连接器轴环上的近端螺纹和远端螺纹，以提供杆和毂的锥形表面之间的接合或密封力的至少两倍，这两者通过旋转轴环相对而被迫在一起 到集线器搞两组线程。 接合的远端螺纹的直径必须足够大，使得轮毂上的近端螺纹可以在套环上的远端螺纹下方通过，以实现近端和远端接合。 安装在杆的未锁定的远端段上的O形环接合未锁定的内毂表面以提供额外的密封力，这在通过适配器提供气体时特别有用。

公开(公告)号：EP2247348A2

公开(公告)日：2010-11-10

申请号：EP08871506.5

申请日：2008-12-30

申请人： E-Z-EM, Inc.

发明人： HENRY, Timothy, G. ,  PRICE, Barbara, B.

IPC分类号： A62D3/30 ,  A62D3/33

CPC分类号： A62D3/36 ,  A61K8/40 ,  A61Q17/00 ,  A62D3/30 ,  A62D3/33 ,  A62D2101/02 ,  A62D2101/04 ,  A62D2101/22 ,  A62D2101/24 ,  A62D2101/26 ,  A62D2101/28 ,  A62D2101/43 ,  A62D2101/45 ,  A62D2101/47 ,  A62D2101/49

摘要： The present invention is directed to a formulation and associated method for neutralizing one or more toxic chemical and/or materials including toxic industrial chemicals and toxic industrial materials, such as irritants, heavy metals, radioactive metals, acids and acid irritants, pesticides, and various agricultural chemicals, (collectively referred to as toxic chemical, materials, or simply toxins) as well as decontaminating surfaces that have come into contact with these agents. As a result, the formulation of the present invention can be used for neutralizing a broad spectrum of toxic chemicals and materials. In one embodiment, the active ingredient comprises 2, 3, butanedione monoxime (also known as diacetyl monoxime (DAM)), and alkali salts thereof such as potassium 2,3-butanedione monoxime (KBDO). The formulation also typically includes a carrier in which the active ingredient is dispersed. In one embodiment, the carrier comprises polyethylene glycol (PEG); monomethoxypolyethylene glycol(mPEG); and combinations and derivatives thereof.

摘要翻译： 本发明涉及一种制剂，和用于中和一种或多种有毒化学品和/或材料，包括有毒工业化学品和有毒工业材料，颜色相关联的方法：如刺激剂，重金属，放射性金属，酸和酸刺激剂，杀虫剂和多种 农业化学品，（由统称为有毒化学品，物质或简单毒素），以及去污表面thathave成与合成剂接触。 其结果是，本发明的制剂可用于中和有毒化学品和材料的广谱。 在一个中，活性成分的实施例包括2,3-丁二酮单肟（因此称为二乙酰单肟（DAM）），以及它们的碱金属盐：如钾2,3-丁二酮单肟（KBDO）。 因此，配制剂通常包括其中活性成分分散的载体。 在一个实施方案中，载体包含聚乙二醇（PEG）; 单甲氧基聚乙二醇（mPEG）; 及其组合和衍生物。

公开(公告)号：EP1492452A4

公开(公告)日：2009-03-25

申请号：EP03723919

申请日：2003-04-05

申请人： E Z EM INC

发明人： LEFERE PHILIPPE ,  WILLIAMS ARCHIE

IPC分类号： A61K47/26 ,  A61B20060101 ,  A61B5/05 ,  A61K49/00 ,  A61K49/04 ,  A61K51/00

CPC分类号： A61K49/0404 ,  A61K49/0004 ,  A61K49/0409

摘要： This invention relates to a colonic residue tagging system, formulation, it and method for use in preparing an individual for a predetermined activity which requires tagging at least some colonic residue in a digestive tract such that a medically and/or diagnostically useful procedure can be performed on the difestive tract. Such predetermined activity includes, but is not limited to, colon screening. In one alternative embodiment, a dietary regimen comprising low residue food is coordinated with the colonic residue tagging regimen, prior to a predetermined activity, thereby resulting in tagged stool such that a medically or diagnostically useful procedure can be performed on the digestive tract. The present invention also provides an individual sufficient amounts of fluids and nutrition while minimizing the amount of stool formation prior to the predetermined activity.

摘要翻译： 本发明涉及一种结肠残留标签系统，其制剂，以及用于制备预定活性的个体的方法，该方法需要在消化道中标记至少一些结肠残留物，从而可以进行医学上和/或诊断上有用的过程 在节日的道路上。 这种预定的活动包括但不限于结肠筛查。 在一个替代实施方案中，包含低残留食物的饮食方案在预定活动之前与结肠残留物标记方案协调，从而导致标记的粪便，使得可以在消化道上进行医学或诊断上有用的程序。 本发明还提供了足够量的流体和营养物，同时使预定活性之前的粪便形成量最小化。

公开(公告)号：EP1940501A2

公开(公告)日：2008-07-09

申请号：EP06826469.6

申请日：2006-10-23

申请人： E-Z-EM, Inc.

发明人： WILLIAMS, Robert, C., Jr. ,  KURZYNA, Peter, M.

IPC分类号： A61M31/00 ,  A61M37/00

CPC分类号： A61M13/003 ,  A61M2202/0225 ,  A61M2205/3344 ,  A61M2205/502 ,  A61M2202/0007

摘要： The present invention is directed to a system, method, and computer program product for controlling the supply of a distending media (such as an insufflating gas) from a distending media source to an endoscopic device so as to prevent the excess venting and/or waste of distending media. More specifically the present invention provides for the detection of a pressure level within a lumen of an endoscopic device and adjusts a supply parameter of the distending media based at least in part on the detected pressure level, and in some cases on the relationship between the detected pressure level and a user-defined threshold.

摘要翻译： 本发明涉及一种系统，方法，以及用于控制膨胀介质的供给计算机程序产品（颜色：如吹入气体）在内窥镜装置从膨胀介质源，从而防止过量的排气和/或废水 的膨胀介质。 更具体地说，本发明提供了用于检测的内窥镜装置的和bestimmt至少基于在所述检测到的压力水平部分的膨胀介质的供给参数的管腔内的压力水平，并且在所检测到的关系某些情况下 压力水平和用户定义的阈值。