摘要:
The present invention provides a safe and effective package (10) for housing a dosage (40), which is easily opened by a user yet provides a secure and contaminant-free environment for the dosage (40) housed within. The package (10) may include a guided tear condition (30) extending along at least one edge of the package, allowing a user to safely and effectively open the package (10) without risk of compromising the dosage (40) housed therein. In some embodiments, the dosage (40) is a substantially flat dosage, such as a film.
摘要:
The present invention relates to packaged orally consumable film dosage units for delivery of actives into the oral cavity. In particular, the packaged pharmaceutical product contains a complexate including a complexing agent and an active, an orally consumable film for delivery of the complexate and a package for containing the orally consumable film. The package includes indicia associated therewith. The indicia identifies the complexate as the active ingredient contained in the film, which is as a regulatory approvable chemical entity. The present invention also relates to methods of labeling, pricing, marketing and satisfying governmental regulations for such packaged pharmaceutical products.
摘要:
The packet structure includes an envelope structure and a tear structure therein. The tear structure provides for tearing of a specific section of the envelope structure to gain access to a film strip which is stored within an internal cavity in the envelope structure. The tear structure has a reduced resistance to tearing relative to an adjoining portion of the envelope structure. The reduced resistance to tearing directs the tearing of the envelope structure to a specific section thereof. The tear structure may alternatively have a pull-string attached within the envelope structure and extending through an aperture therein to a location outside of the envelope structure. The location of the aperture and attachment of the pull-string within the envelope structure directs the tearing of the envelope structure to a specific section thereof.
摘要:
The invention relates to a fast-dissolving film product containing at least one drug; and a water soluble polymer composition. The invention further relates to methods of administering the film product. The method includes administering the film to the oral cavity of a subject in need of the drug; and administering a fluid in the oral cavity while the film is present therein to substantially dissolve the film and form a solution or dispersion thereof to be ingested by the subject. Desirably, ingestion of the thus-formed solution or dispersion provides increased blood levels of the drug as compared to the film taken without the fluid.
摘要:
The present invention relates to a system and method for dispensing a therapeutically effective amount of dosage containing a medicament including an instrument for inputting data from a user, analyzing the inputted data to determine an appropriate amount of medicament to be administered to the user, and a dispenser for sizing and dispensing a therapeutically effective amount of the medicament. The medicament may be in the form of a continuous roll of oral thin film including the medicament.
摘要:
The present invention relates to products and methods for treatment of various symptoms in a patient, including treatment of pain suffered by a patient. The invention more particularly relates to self-supporting dosage forms which provide an active agent while providing sufficient buccal adhesion of the dosage form. Further, the present invention provides a dosage form which is useful in reducing the likelihood of diversion abuse of the active agent.
摘要:
The present invention is directed at compositions and products, and methods of making and administering such compositions and products, including for the treatment of mammals and particularly humans. Nanoparticles having a core and a corona of ligands covalentJy linked to the core, wherein differing species of peptides are bound to the nanoparticles and incorporated into various dosage forms.