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11.发明公开
公开(公告)号：EP4186949A1
公开(公告)日：2023-05-31
申请号：EP20957728.7
申请日：2020-10-16
发明人： OISHI, Kou , UENO, Toshiya , MIYAMOTO, Yoshiaki
IPC分类号： C09D5/00 , C09D163/00 , C09D183/04 , C09D7/61
摘要： The present invention provides a coating agent composition capable of making interference fringes inconspicuous and suppressing the generation of cracks during the production of a hard coat layer without blending fine particles of metal oxides such as zirconium oxide and titanium oxide in an optical article in which a hard coat layer or a functional layer including a primer layer and a hard coat layer is formed on a plastic layer having a high refractive index. The coating agent composition comprises a trifunctional silane coupling agent and a bifunctional silane coupling agent in a solid content ratio of 95:5 to 10:90.
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公开(公告)号：EP3611178A1
公开(公告)日：2020-02-19
申请号：EP18784209.1
申请日：2018-03-01
发明人： ASAI, Tomohiro , OKU, Naoto , MAEDA, Noriyuki , FUKATA, Naofumi , TOMITA, Koji
IPC分类号： C07F9/10 , A61K9/16 , A61K31/7088 , A61K47/10 , A61K47/24 , A61K47/28 , A61K48/00 , A61P43/00
摘要： An object is to provide a lipid particle that is not positively charged at a pH of the body fluid (typically in the neutral range), and that enables efficient onset of the effect of a medicinal substance encapsulated in the lipid particle; and to provide a lipid for forming the lipid particle. The object is achieved by the phospholipid represented by formula (1), and a lipid particle containing the phospholipid:
wherein R 1 and R 2 are identical or different, and represent a chain hydrocarbon group, m represents 1 or 2, n represents 1 or 2, and p represents an integer of 1 to 4.-
公开(公告)号：EP0685488B1
公开(公告)日：1998-04-15
申请号：EP94903009.2
申请日：1993-12-16
CPC分类号： C07J9/00
摘要： A process for producing high-quality cholesterol by selectively reducing impurities contained in crude cholesterol, mainly desmosterol, into cholesterol. The process can provide high-purity cholesterol containing at most 0.3 % of desmosterol and at most 0.5 % of dihydrocholesterol and having a purity of at least 99 % after reduction and crystallization in a yield of 85 % or above.
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公开(公告)号：EP0392018B1
公开(公告)日：1995-09-06
申请号：EP89906454.7
申请日：1989-06-05
IPC分类号： C11B11/00
CPC分类号： C11B11/005
摘要： The invention provides a process for purifying raw lanolins containing agricultural chemicals by removing the residual agricultural chemicals therefrom, which comprises subjecting the raw lanolins to at least one of the step (1) of hydrogenation in a molten state or in an organic solvent in the presence of a hydrogenation catalyst at a temperature of 60 to 210°C under a hydrogen pressure of 1 atm or more with a hydrogen consumption of 0.001 to 0.05 wt. % based on the raw lanolin, the step (2) of distillation in vacuo at a temperature of 150 to 280°C under an absolute pressure of 10 to 500 x 10-3 mmHg, and the step (3) of adsorption on a resin selected from among those containing styrene-divinylbenzene as a skeleton, those containing acrylic ester as a skeleton and polystyrene resins and having a micropore size of about 10 to 250 Å or on a crystalline aluminosilicate having an internal diameter of about 9 to 13 Å.
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15.发明公开LANOLIN FATTY ACIDS, SEPARATION THEREOF, AND COSMETIC AND EXTERNAL PREPARATION 失效羊毛脂脂肪酸，它们的分离和cosmetic-和外用制剂。
公开(公告)号：EP0596135A1
公开(公告)日：1994-05-11
申请号：EP93909422.3
申请日：1993-04-26
发明人： MIYAZAKI, Katsuhiko , KAWASAKI, Toshiyuki , KATO, Isao , NODA, Kenji , OSAKI, Masakatsu , NAYESHIRO, Hidekazu , ANDO, Hideya
CPC分类号： C11C3/00 , A61K8/361 , A61K8/925 , A61Q5/02 , A61Q5/12 , A61Q19/00 , C07C53/126 , C07C59/01 , C11B11/005 , C11C1/005 , C11C1/103
摘要： A process for producing a- and ω-hydroxy fatty acids by treating lanolin fatty acids with boric acid to esterify hydroxy fatty acids contained therein, distilling the reaction product in a vacuum to separate and purify the borates of the hydroxy fatty acids and non-hydroxy fatty acids, hydrolyzing the purified borates, and distilling the hydrolyzate; each of the lanolin fatty acids and esters thereof thus obtained; and cosmetics and external preparations prepared therefrom. The invention process provides light-colored, nearly odorless lanolin fatty acids readily and efficiently on an industrial scale, and the obtained acids can be utilized in the fields of medicines and cosmetics.
摘要翻译： 用于产生α的方法 - ω-羟基脂肪酸通过处理羊毛脂脂肪酸与硼酸和酯化其中所含羟基脂肪酸，蒸馏反应产物在真空中分离和纯化的羟基脂肪酸和非羟基的硼酸盐 脂肪酸，水解纯化的硼酸盐，并蒸馏该水解产物; 每个羊毛脂脂肪酸及其酯由此获得的; 化妆品和外用制剂制备了那里。 本发明的方法在工业规模方便有效地提供有关浅色，近无臭羊毛脂脂肪酸，并且所获得的酸可以在药品和化妆品领域中使用。
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公开(公告)号：EP0392018A1
公开(公告)日：1990-10-17
申请号：EP89906454.7
申请日：1989-06-05
IPC分类号： C11B11/00
CPC分类号： C11B11/005
摘要： The invention provides a process for purifying raw lanolins containing agricultural chemicals by removing the residual agricultural chemicals therefrom, which comprises subjecting the raw lanolins to at least one of the step (1) of hydrogenation in a molten state or in an organic solvent in the presence of a hydrogenation catalyst at a temperature of 60 to 210° C under a hydrogen pressure of 1 atm or more with a hydrogen consumption of 0.001 to 0.05 wt. % based on the raw lanolin, the step (2) of distillation in vacuo at a temperature of 150 to 280 C under an absolute pressure of 10 to 500 x 10 -3 mmHg, and the step (3) of adsorption on a resin selected from among those containing styrene-divinylbenzene as a skeleton, those containing acrylic ester as a skeleton and polystyrene resins and having a micropore size of about 10 to 250 Å or on a crystalline aluminosilicate having an internal diameter of about 9 to 13 A.
摘要翻译： 一种净化羊毛脂的方法，其包括以下方法中的至少一种：1）在有机溶剂中或在60-210℃的熔融条件下，在氢气氛（1大气压或1小时）中热处理羊毛脂（A） 更高）和在氢化催化剂存在下。 H2的消耗量为羊毛脂（A）的0.001〜0.05重量％。 （A）包含至少一种农业化学品HCB，αbetamamma-BHC，γ-BHC，ALD + OLD，DDE + DDT，END，DZN，BPE，DCP和alphabeta-CVP。 2）在150-280℃下（A）的真空蒸馏（10-500×10 -MHgHg）。 3）在树脂（B）或结晶铝硅酸盐（C）上吸收（A）。 （B）是苯乙烯 - 二乙烯基苯树脂，丙烯酸酯树脂或聚苯乙烯树脂，并且具有10-250埃的细孔尺寸（C）的内径为9-13埃。
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公开(公告)号：EP0195311A2
公开(公告)日：1986-09-24
申请号：EP86102861.1
申请日：1986-03-05
CPC分类号： C12P7/6436 , C07J9/00 , C11C3/003 , C11C3/04 , C12P1/00 , C12P7/6454
摘要： A process for reacting (1) a component selected from the group consisting of sterols and branched aliphatic primary or secondary alcohols having 14 to 32 carbon atoms, and (2) a component selected from the group consisting of fatty acids and fatty acid esters in contact with an enzyme selected from the group consisting of lipase and cholesterol esterase or with the selected enzyme in an immobilized form, in a system selected from the group consisting of an aqueous medium and water-containing organic solvent to prepare a fatty acid ester of the component (1).
摘要翻译： 一种使（1）选自甾族醇和具有14至32个碳原子的支链脂族伯或仲醇的组分的组分与（2）选自脂肪酸和脂肪酸酯的组分的组分反应的方法 在选自含水介质和含水有机溶剂的系统中，选自脂肪酶和胆固醇酯酶的酶或选定的酶以固定形式选择的酶，以制备组分的脂肪酸酯 （1）。
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18.发明授权Method for preparing lipid powder for use in preparing liposomes and method for preparing liposomes 失效用于制备脂质体的脂质粉末的制备方法和用于制备脂质体的方法
公开(公告)号：EP0357005B1
公开(公告)日：1993-03-03
申请号：EP89115945.1
申请日：1989-08-29
IPC分类号： A61K9/127
CPC分类号： A61K9/1277 , Y10S159/10
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19.发明公开GLYCOSIDE DERIVATIVES, POLYMERS CONTAINING GLYCOSIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND USE OF SAID POLYMERS 失效甘氨酸衍生物，含有甘氨酸衍生物的聚合物，其制备方法和使用聚合物
公开(公告)号：EP0394496A4
公开(公告)日：1992-10-28
申请号：EP89911861
申请日：1989-10-25
发明人： KITAZAWA, SADAYA YANAGI-MANSION 506 , OKUMURA, MASAKAZU 119-112, NOGUCHI , KOJIMA, MASAKI , KINOMURA, KEISUKE HIGASHIKAKOGAWA-HAITAUN A-703 , SAKAKIBARA, TOSHIYUKI MAIKODAI-GREEN-MANSION 220
IPC分类号： A61L33/06 , C07H15/08 , C07H15/10 , C08F20/28 , C08F20/30 , C08F290/00 , C08F290/10 , C08F299/02 , C08J7/04 , G02B1/04 , C07H1/00 , C09K3/00
CPC分类号： C07H15/10 , A61L33/064 , C07H15/08 , C08F20/28 , C08F20/30 , C08F290/10 , C08F299/024 , C08J7/047 , C08J2369/00 , C08J2433/00 , G02B1/041 , Y02P20/55 , C08L33/14
摘要： The invention provides glycoside derivatives represented by general formula (I) (wherein G-O- represents a sugar residue free of the protective group, r represents hydrogen or methyl, m represents 1 or 2, n represents an integer of 1 to 4, and l represents an integer of 1 or more provided that l « n), polymers containing said glycoside derivatives, a process for their preparation, and uses of said polymers.
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20.发明公开Glycosidation catalyst and process for preparing glycoside derivatives 失效Glycosidationskatalysator和Verfahren zur Herstellung von Glycosid-Derivaten。
公开(公告)号：EP0263027A1
公开(公告)日：1988-04-06
申请号：EP87402167.8
申请日：1987-09-29
IPC分类号： B01J27/188 , B01J27/198 , B01J23/22 , B01J23/24 , C07H15/04 , C07H15/14 , B01J23/16
CPC分类号： C07H15/18 , B01J23/16 , B01J27/188 , B01J27/198 , C07H15/04
摘要： Disclosed are a glycosidation catalyst comprising at least one of heteropoly acids represented by the formula
H a X p M q O r ·bH₂O
wherein X is P, As, Si or Ge, M is at least one species selected from the group consisting of Mo, W and V, a is 3 4 or 6, b is an integer of 0 to 30, p is 1 or 2, q is 12 or 18, and r is 40 or 62, with the proviso that when X is P or As, a is 3 or 6; when X is Si or Ge, a is 4; and further (1) when X is P or As and a is 3, or when X is Si or Ge and a is 4, M is at least one species selected from the group consisting of Mo, W and V, p is 1, q is 12 and r is 40; and (2) when X is P or As and a is 6, M is Mo or W, p is 2, q is 18 and r is 62, and a process for preparing a glycoside derivative by using said catalyst.摘要翻译： 公开了一种糖苷化催化剂，其包含由式H aX pM qO r.bH 2 O表示的杂多酸中的至少一种，其中X为P，As，Si或Ge，M为选自Mo，W和 V，a为3或6，b为0〜30的整数，p为1或2，q为12或18，r为40或62，条件是当X为P或As时，a为 3或6; 当X为Si或Ge时，a为4; 进一步（1）当X为P或As且a为3时，或当X为Si或Ge且a为4时，M为选自Mo，W和V中的至少一种，p为1， q为12，r为40; 和（2）当X为P或As，a为6时，M为Mo或W，p为2，q为18，r为62，通过使用所述催化剂制备糖苷衍生物的方法。
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