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    INTRACORONARY INFUSION OF IGF-1 FOR MYOCARDIAL REPAIR
    11.
    发明授权
    INTRACORONARY INFUSION OF IGF-1 FOR MYOCARDIAL REPAIR 有权
    IGF-1在心脏修复中的应用

    公开(公告)号：EP3047861B1

    公开(公告)日：2017-10-18

    申请号：EP16152830.2

    申请日：2009-11-27

    申请人： University College Cork-National University of Ireland, Cork

    发明人： Caplice, Noel

    IPC分类号： A61L29/04 ,  A61L29/16

    CPC分类号： A61L29/048 ,  A61L29/16 ,  A61L2300/414 ,  A61L2300/602

    摘要： Provided herein are methods for treating an individual having (suffering from) an acute myocardial infarction and drug eluting stents useful for treating such individuals. These methods include treating an individual by introducing, such as by surgically inserting, at a site of an acute coronary artery occlusion upstream of the site of acute myocardial infarction, a drug eluting stent (DES) that is capable of eluting from 25pg to 950pg of IGF-1 directly into the coronary circulation. The treatment is specifically directed to stimulation of repair or survival of damaged cardiac muscle or left ventricular remodeling.

    Opto-fluidic microsystem and method
    19.
    发明公开
    Opto-fluidic microsystem and method 审中-公开
    Mikrosystem und Verfahren

    公开(公告)号：EP2833136A1

    公开(公告)日：2015-02-04

    申请号：EP13178682.4

    申请日：2013-07-31

    申请人： University College Cork

    发明人： O'Brien, Peter ,  Ryan, Evan ,  O'Murchu, Cian

    IPC分类号： G01N30/16 ,  G01N30/60 ,  G01N30/74

    CPC分类号： G01N30/16 ,  B01L3/5027 ,  G01N30/6095 ,  G01N30/74

    摘要： The invention relates to the development of a 'fluidic injection' component or module for use with micro- and/or nano-HPLC systems. It utilises a novel optical based system to detect the small liquid sample to be injected into the HPLC separation column. The invention includes the use of an immiscible liquid, for example an oil, that is intentionally coloured or naturally fluorescent to buffer the sample on either side of the injection channel so the position of the sample can be optically or visually detected.

    摘要翻译： 本发明涉及用于微量和/或纳米HPLC系统的“流体注射”组分或模块的开发。 它利用新型的光学系统来检测要注入HPLC分离柱的小液体样品。 本发明包括使用有意着色或天然荧光的不混溶液体（例如油）来缓冲注入通道两侧的样品，因此可以光学或目视检测样品的位置。

    An edible snack food product having a low water content and a high solids content, and a method for the production thereof
    20.
    发明公开
    An edible snack food product having a low water content and a high solids content, and a method for the production thereof 审中-公开
    食用快餐状食品具有低水含量和高固体含量，以及它们的制备方法

    公开(公告)号：EP2783577A1

    公开(公告)日：2014-10-01

    申请号：EP13161201.2

    申请日：2013-03-26

    申请人： University College Cork

    发明人： ROOS, Yrjo

    IPC分类号： A23L1/164 ,  A23L1/18 ,  A23L1/217

    CPC分类号： A23L19/05 ,  A23L7/122 ,  A23P20/105

    摘要： A process for making an edible snack food product having a low water content and a high solids content is described. The process comprises a step of providing an edible porous body, for example a freeze-dried fruit or vegetable slice or an extruded cereal product, and coating the body in a high-solids polymer solution, for example 25% (w/w) whey protein isolate, such that the polymer solution infuses into the pores at or close to the surface of the body but does not rehydrate the porous body. Coating may be achieved by spraying the product with the polymer solution or by briefly immersing the porous body in the solution. The coated porous body is then heated to a high temperature to dehydrate the infused polymer solution. This results in closure of the pores at or close to the surface of the porous body.

    摘要翻译： 描述了一种用于制造具有低水含量和高固体含量的食用零食食品产品的过程。 该方法包括提供上食用多孔体，例如冷冻干燥的水果或蔬菜片或挤出谷物产品，和涂布体在高固体含量的聚合物溶液，例如25％（重量/重量）的步骤乳清 蛋白分离物，检查做了聚合物溶液灌输到位于或靠近身体的表面上的孔，但不再水合多孔体。 涂层可以通过与聚合物溶液或通过短时间浸渍该多孔体中的溶液喷雾的产品来实现。 经涂覆的多孔体，然后加热至高温脱水输注聚合物溶液。 这导致在孔的闭合或接近多孔体的表面上。