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公开(公告)号：EP1233975A4
公开(公告)日：2004-07-07
申请号：EP00978314
申请日：2000-11-01
IPC分类号： G01N33/50 , A61K31/7088 , A61K35/76 , A61K38/00 , A61K45/00 , A61K48/00 , A61P1/02 , A61P1/04 , A61P1/16 , A61P1/18 , A61P3/10 , A61P5/00 , A61P5/14 , A61P7/00 , A61P7/02 , A61P7/04 , A61P7/06 , A61P7/08 , A61P9/00 , A61P9/02 , A61P9/04 , A61P9/06 , A61P9/10 , A61P9/12 , A61P9/14 , A61P11/00 , A61P11/06 , A61P13/02 , A61P13/12 , A61P15/08 , A61P17/00 , A61P17/02 , A61P17/04 , A61P17/06 , A61P19/02 , A61P19/04 , A61P19/06 , A61P19/08 , A61P19/10 , A61P21/00 , A61P21/04 , A61P25/00 , A61P25/02 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/24 , A61P25/28 , A61P27/02 , A61P27/06 , A61P27/16 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P31/18 , A61P33/00 , A61P33/06 , A61P35/00 , A61P35/02 , A61P35/04 , A61P37/02 , A61P37/04 , A61P37/06 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/02 , C12Q1/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C07H21/02 , A61K38/17 , C12N15/12 , G01N33/68
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公开(公告)号：EP1210370A4
公开(公告)日：2004-06-09
申请号：EP00957369
申请日：2000-08-10
发明人： RUBEN STEVEN M , YOUNG PAUL E , BAKER KEVIN P
IPC分类号： C12N15/09 , A61K38/00 , A61K45/00 , A61K48/00 , A61P1/14 , A61P1/16 , A61P9/10 , A61P25/00 , A61P25/28 , A61P29/00 , A61P31/04 , A61P31/12 , A61P31/18 , A61P35/00 , A61P37/02 , A61P37/06 , A61P43/00 , C07K14/47 , C07K14/705 , C07K14/715 , C07K16/28 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12P21/02 , C12Q1/68 , C07H21/04 , C12N15/63
CPC分类号： C12Q1/6837 , A61K38/00 , C07K14/70578 , C12Q1/6809 , C12Q2565/513 , C12Q2525/191 , C12Q2521/313
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公开(公告)号：EP1392817A4
公开(公告)日：2004-05-26
申请号：EP02736513
申请日：2002-03-26
发明人： ROSEN CRAIG A , RUBEN STEVEN M
摘要： The present invention relates to human secreted polypeptides, and isolated nucleic acid molecules encoding said polypeptides, useful for diagnosing and treating diabetes mellitus and/or conditions related to diabetes. Antibodies that bind these polypeptides are also encompassed by the present invention. Also encompassed by the invention are vectors, host cells, and recombinant and synthetic methods for producing said polynucleotides, polypeptides, and/or antibodies. The invention further encompasses screening methods for identifying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further encompasses methods and compositions for inhibiting or enhancing the production and function of the polypeptides of the present invention.
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公开(公告)号：EP1206233A4
公开(公告)日：2004-04-14
申请号：EP00942939
申请日：2000-06-20
发明人： RUBEN STEVEN M , YOUNG PAUL E
IPC分类号： G01N33/50 , A61K31/711 , A61K35/76 , A61K38/48 , A61K39/395 , A61K48/00 , A61P3/10 , A61P5/14 , A61P7/00 , A61P7/04 , A61P7/06 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/08 , A61P13/12 , A61P17/00 , A61P21/04 , A61P25/00 , A61P27/02 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P35/00 , A61P35/02 , A61P35/04 , A61P37/00 , A61P37/02 , A61P37/06 , A61P43/00 , C07K16/40 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/64 , C12N15/09 , C12Q1/68 , G01N33/15 , G01N33/53 , A61K6/00 , C07K14/51
CPC分类号： C12N9/6424 , C12Q1/6883 , C12Q2600/156
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公开(公告)号：EP1235845A4
公开(公告)日：2003-06-25
申请号：EP00978315
申请日：2000-11-01
IPC分类号： G01N33/53 , A61K31/7088 , A61K38/00 , A61K48/00 , A61P15/08 , A61P25/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , G01N33/566 , C07H21/04 , C07H21/02 , C07K5/00 , C07K14/00 , C12N15/63 , C12N15/85 , C12N15/86 , C12Q1/68
CPC分类号： C07K14/47
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公开(公告)号：EP1181303A4
公开(公告)日：2003-04-09
申请号：EP00920141
申请日：2000-04-06
IPC分类号： G01N33/50 , A61K31/713 , A61K38/00 , A61K48/00 , A61P1/16 , A61P9/00 , A61P9/06 , A61P9/10 , A61P11/06 , A61P17/06 , A61P19/02 , A61P25/02 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/04 , A61P31/18 , A61P35/00 , A61P35/02 , A61P37/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/02 , C12Q1/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C07H21/02 , C07H21/04 , C12N1/20 , C12N15/00 , C12N15/63 , C12N15/70 , C12N15/74
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公开(公告)号：EP1165606A4
公开(公告)日：2003-04-09
申请号：EP00916586
申请日：2000-03-22
IPC分类号： G01N33/50 , A61K38/00 , A61K48/00 , A61P3/00 , A61P3/04 , A61P5/14 , A61P7/02 , A61P7/06 , A61P9/10 , A61P9/14 , A61P11/00 , A61P11/06 , A61P13/12 , A61P17/00 , A61P17/02 , A61P19/02 , A61P21/04 , A61P25/00 , A61P25/02 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P27/00 , A61P27/02 , A61P29/00 , A61P31/04 , A61P37/00 , A61P37/04 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12N15/19 , C12P21/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C07H21/00 , C12N15/63 , C12N15/70 , C12N15/74 , C12N15/79
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18.发明公开IMMUNOGLOBULIN SUPERFAMILY POLYNUCLEOTIDES, POLYPEPTIDES, AND ANTIBODIES 审中-公开多核苷酸，多肽和IMMUNOGLOBULINSUPERFAMILIE抗体
公开(公告)号：EP1212407A4
公开(公告)日：2003-04-02
申请号：EP00959538
申请日：2000-08-29
发明人： YOUNG PAUL E , RUBEN STEVEN M , SHI YANGGU
IPC分类号： G01N33/50 , A61K31/7088 , A61K38/00 , A61K39/395 , A61K45/00 , A61K48/00 , A61P7/00 , A61P9/10 , A61P17/00 , A61P25/00 , A61P29/00 , A61P31/00 , A61P35/00 , A61P37/02 , A61P37/08 , C07K14/47 , C07K14/705 , C07K16/18 , C07K16/42 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12N15/13 , C12P21/02 , C12P21/08 , G01N33/15 , G01N33/53 , G01N33/566 , C12N15/63 , C12N15/64
CPC分类号： C07K14/70503 , A61K38/00
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公开(公告)号：EP1179060A4
公开(公告)日：2003-03-26
申请号：EP00935903
申请日：2000-05-11
发明人： ROSEN CRAIG A , RUBEN STEVEN M , MOORE PAUL A , YOUNG PAUL E , KOMATSOULIS GEORGE A , BIRSE CHARLES E , DUAN ROXANNE D , FLORENCE KIMBERLY A , SOPPET DANIEL R
IPC分类号： G01N33/53 , A61K31/711 , A61K38/00 , A61K39/395 , A61K48/00 , A61P1/04 , A61P7/00 , A61P7/04 , A61P7/06 , A61P9/10 , A61P11/06 , A61P17/02 , A61P17/06 , A61P17/12 , A61P19/02 , A61P25/02 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/04 , A61P31/18 , A61P35/00 , A61P35/02 , A61P37/02 , A61P37/04 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/02 , C12Q1/02 , C12Q1/68 , G01N33/566 , C12N15/11 , C07H21/04 , C07K14/00
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
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公开(公告)号：EP1165590A4
公开(公告)日：2003-02-26
申请号：EP00916354
申请日：2000-03-16
IPC分类号： G01N33/53 , A61K35/36 , A61K38/00 , A61K48/00 , A61P17/02 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/24 , A61P25/28 , A61P29/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/02 , C12Q1/02 , C12Q1/68 , G01N33/566 , G01N33/68 , C07H21/04 , C07K14/00 , C07K16/00 , C12N15/00 , C12N15/63 , C12N15/85 , C12N15/86
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