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公开(公告)号：EP3348214A1
公开(公告)日：2018-07-18
申请号：EP18151191.6
申请日：2014-02-03
申请人： Medinol Ltd.
发明人： RICHTER, Jacob , PANSKY, Amir
CPC分类号： A61M25/008 , A61B17/22012 , A61B2017/22001 , A61B2017/22015 , A61B2017/22094 , A61B2090/064 , A61M2025/1093
摘要： An apparatus, system and method for re-canalization or opening a passage through an occlusion in a blood vessel is provided. The apparatus and method, which are appropriate for cardiovascular and peripheral vessels, use a pulling member and a spring member, for example a compression spring, to oscillate a drilling component. The drilling component at the distal end of the catheter tip has combined longitudinal stiffness for penetrating a total or partial occlusion and high axial (lateral) flexibility to improve deliverability and crossability of a catheter through a partially occluded vessel or a tortuous vessel, and may taper distally. The system of the invention includes the apparatus and a control unit to permit adjustment of the frequency or amplitude of oscillation of the drilling component. Also provided is a method for oscillating a drilling component using a pulling member and a spring member and a method of traversing an occlusion.
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公开(公告)号：EP1703856B1
公开(公告)日：2013-02-20
申请号：EP04806450.5
申请日：2004-12-21
申请人： MEDINOL LTD.
发明人： RICHTER, Jacob
IPC分类号： A61F2/90
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2230/0054
摘要： An intravascular stent especially suited for implanting in curved arterial portion. The stent retains longitudinal flexibility after expansion. The stent is formed of intertwined meander patterns forming triangular cells. The cells are adapted to provide radial support, and also provide longitudinal flexibility after expansion. The cells also provide increase coverage of a vessel wall. Loops in the stent are disposed and adapted to cooperate, so that after expansion of said stent within a curved lumen, the stent is curved and cells on the outside of the curve open in length, but narrow in width, whereas cells on the inside of the curve shorten in length, but thicken in width to maintain a density of the stent element area which is much more constant than otherwise between the inside and outside of the curve.; The stent also minimizes flaring out by eliminating free loops of the radially supporting circumferential bands of loops.
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公开(公告)号：EP2421484A1
公开(公告)日：2012-02-29
申请号：EP10728283.2
申请日：2010-04-21
申请人： Medinol Ltd
发明人： RICHTER, Jacob
摘要： An expandable helical stent is provided, wherein the stent may be formed of a main stent component and a securement. The main stent component is formed from a flat strip having one or more undulating side bands (401, 402) that may be connected to form geometrically shaped cells (430) and are helically wound to form a stent. The helical coils of the main stent component may be spaced apart or nestled to each other. The nestling of the undulation of adjacent helical windings contributes to maintaining the tubular shape and uniformity of the helically coiled stent. Alternatively, the flat strip may comprise a single undulating pattern. At the ends of the main stent component are end bands (407), which when wound, form a cylindrical ring. In one embodiment, one or more struts of the main stent component may have a width sufficient to include one or more fenestrations. The fenestrated struts may be connected by loops or turns wherein the material is narrower than that of the fenestrated struts to provide enhanced flexibility. The helical tubular is maintained with a securement.
摘要翻译： 提供了可扩张螺旋支架，其中支架可以由主支架部件和固定件形成。 主支架部件由具有一个或多个起伏的边带（401,402）的扁平条带形成，所述边带可以被连接以形成几何形状的细胞（430）并螺旋形地缠绕以形成支架。 主支架部件的螺旋线圈可以彼此间隔开或嵌套。 相邻螺旋绕组起伏的起伏有助于保持螺旋盘绕支架的管状和均匀性。 或者，扁平条可以包括单个起伏图案。 在主支架部件的端部处是端部带（407），当缠绕时形成圆柱形环。 在一个实施例中，主支架部件的一个或多个支柱可以具有足以包括一个或多个开窗的宽度。 开窗支柱可以通过环或匝连接，其中材料比开窗支柱的材料窄，以提供增强的柔性。 螺旋管被保持固定。
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公开(公告)号：EP1996113A2
公开(公告)日：2008-12-03
申请号：EP07733978.6
申请日：2007-03-14
申请人： MEDINOL LTD.
发明人： RICHTER, Jacob
IPC分类号： A61F2/00
CPC分类号： A61F2/88 , A61F2/07 , A61F2/91 , A61F2210/0004 , A61F2220/005 , A61F2250/0067 , A61L31/022 , A61L31/10 , C08L27/18
摘要： An expandable stent is provided, wherein the stent is advantageously formed of at least one amorphous metal alloy and a biocompatible material. The stent is formed from flat metal in a helical strip which is wound to form a tubular structure. The tubular structure is not welded but rather is wrapped or coated with a biocompatible material in order to maintain the amorphous metal in its tubular configuration. Said stent can be balloon expanded or self expanding.
摘要翻译： 提供了一种可扩张支架，其中支架有利地由至少一种非晶金属合金和生物相容性材料形成。 支架由螺旋形条中的扁平金属形成，其被卷绕以形成管状结构。 管状结构不是焊接的，而是用生物相容性材料包裹或涂覆，以便将非晶态金属保持在其管状结构中。 所述支架可以是气囊膨胀的或自膨胀的。
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公开(公告)号：EP1424963A2
公开(公告)日：2004-06-09
申请号：EP02767765.7
申请日：2002-09-06
申请人： MEDINOL LTD.
发明人： PINCHASIK, Gregory , RICHTER, Jacob
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2230/0054 , A61F2250/0014 , A61F2250/0067
摘要： An intravascular stent (fig. 10) especially suited for implanting in curved arterial portions. The stent (fig. 10) is formed of intertwined meander patterns forming triangular cells (804). The triangular cells (804) are adapted to provide radial support, and longitudinal flexibility after expansion. The triangular cells (804) provide increased coverage of a vessel wall. The stent (fig. 10) can have different portions adapted to optimize radial support or to optimize longitudinal flexibility. The stent (fig. 10) is curved and cells on the outside of the curve open in length, but narrow in width whereas cells on the inside of the curve shorten in length but thicken in width to maintain a density of stent element area which much more constant than otherwise between the inside and the outside of the curve. As a result, when the stent is coated with a medicine the more constant density of stent elements results in an even dose being applied to the inside wall of the lumen, avoiding the possibility that a toxic dose be supplied at one area while a less than effective dose is applied to another area.
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公开(公告)号：EP3501555A1
公开(公告)日：2019-06-26
申请号：EP18199954.1
申请日：2007-03-09
申请人： Medinol Ltd.
发明人： RICHTER, Jacob
摘要： A drug-coated stent and a method for fabricating the stent are disclosed. The stent has an originally flat pattern and connection points where the sides of the flat pattern are joined. The method includes the steps of a) cutting a stent pattern into a flat piece of metal thereby to produce a metal pattern, b) spraying the flat metal stent pattern with a polymer and a drug, c) deforming the metal pattern so as to cause two opposing sides to meet, and d) joining the two opposing sides at least at one point. Substantially no portion of the stent projects into the lumen of the stent when the stent is expanded against the internal wall of a blood vessel.
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公开(公告)号：EP3178502A1
公开(公告)日：2017-06-14
申请号：EP17153564.4
申请日：2007-03-09
申请人： Medinol Ltd.
发明人： RICHTER, Jacob
CPC分类号： A61L31/16 , A61F2/91 , A61F2/915 , A61F2002/91541 , A61F2002/91558 , A61F2230/0054 , A61F2240/001 , A61F2250/0067 , A61F2310/0097 , A61L31/10 , A61L2300/606 , C25F3/00 , C25F3/14
摘要： A drug-coated stent and a method for fabricating the stent are disclosed. The stent has an originally flat pattern and connection points where the sides of the flat pattern are joined. The method includes the steps of a) cutting a stent pattern into a flat piece of metal thereby to produce a metal pattern, b) spraying the flat metal stent pattern with a polymer and a drug, c) deforming the metal pattern so as to cause two opposing sides to meet, and d) joining the two opposing sides at least at one point. Substantially no portion of the stent projects into the lumen of the stent when the stent is expanded against the internal wall of a blood vessel.
摘要翻译： 公开了药物涂层支架和制造该支架的方法。 支架具有原始平坦的图案和平面图案的侧面连接处的连接点。 该方法包括以下步骤：a）将支架图案切割成平坦金属片，从而产生金属图案; b）用聚合物和药物喷射平坦金属支架图案; c）使金属图案变形，从而引起 两个相对的边相遇，以及d）至少在一个点处连接两个相对的边。 当支架相对于血管的内壁膨胀时，支架的基本上没有部分伸入支架的内腔中。
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公开(公告)号：EP2967933A2
公开(公告)日：2016-01-20
申请号：EP14744147.1
申请日：2014-03-14
申请人： Medinol Ltd.
发明人： RICHTER, Jacob , WEIZMAN, Oleg , BELOBROVY, Igor
CPC分类号： A61F2/88 , A61F2/91 , A61F2220/0058
摘要： An expandable helical stent with a securement is provided. The stent is formed from flat or tubular metal in a helical coiled structure which has an undulating pattern. The main stent component may be formed of a single helically coiled component. Alternatively, a plurality of helically coiled ribbons may be used to form a stent heterogeneous in design, material, or other characteristic. The helical tubular structure may be secured with a securement, such as a weld, interlock or a polymer, to maintain the helical coils in a tubular configuration. The helical coils of the main stent component may be spaced apart or nestled to each other. The nestling of the undulation of adjacent helical coils contributes to maintaining the tubular shape of the helically coiled stent. In addition, the nestling of helical coils may prevent the polymer layer from sagging at any point between cycles of the helical coils.
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公开(公告)号：EP2187987B1
公开(公告)日：2014-07-09
申请号：EP08807166.7
申请日：2008-03-26
申请人： Medinol. LTD.
发明人： RICHTER, Jacob
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/828 , A61F2002/91541 , A61F2210/0004 , A61F2250/0071 , A61L31/022 , A61L31/042 , A61L31/148 , C08L67/00
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公开(公告)号：EP2421484B1
公开(公告)日：2019-11-06
申请号：EP10728283.2
申请日：2010-04-21
申请人： Medinol Ltd.
发明人： RICHTER, Jacob
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