摘要:
A prosthetic heart valve includes a base and a plurality of polymeric leaflets. Each leaflet has a root portion coupled to the base, and each leaflet has an edge portion substantially opposite the root portion and movable relative to the root portion to coapt with a respective edge portion of at least one of the other leaflets of the plurality of leaflets. Each leaflet includes) at least two polymers along at least one portion of the leaflet, and each leaflet has a composition gradient of each of the at least two polymers along at least one portion of the leaflet.
摘要:
Various embodiments for a composite endovascular device (and variations thereof) that include an inner polymer structure and an outer thin-film shape memory structure. The inner polymer structure extends from a distal end to a proximal end along a longitudinal axis. The outer thin-film shape-memory structure has an inner thin-film surface coupled to the outer surface of the inner polymer structure from the distal end to the proximal end with a retrieval member at the proximal end to allow for the prosthesis to be retrieved after placement in a body vessel. The inner polymeric structure can be blended with a suitable bio-active agent or the agent can be loaded into the pores. The device can be permanent or temporary by virtue of being retrievable.
摘要:
The invention relates to a method for producing a storable molded body made of bacterial cellulose and a molded body produced according to the method. A preferred method includes providing a molded body made of bacterial cellulose. Optionally, mechanically pressing the entire molded body or parts of the molded body at temperatures in the range of 10° C. to 100° C. and pressures in the range of 0.01 to 1 MPa for a pressing time of 10-200 min. Treating the molded body with a solution of 20% by weight to 50% by weight of glycerol and 50% by weight to 80% by weight of a C1-C3-alcohol/water mixture. Drying the treated molded body.
摘要:
The invention relates to a prosthetic liner, comprising: a moulded polymer like liner body for receiving an amputation limb of a person, the liner body having a closed distal end and an open proximal end, wherein the liner comprises at least one thickening in a first region and/or in a second region, wherein the liner body and the at least one thickening are made from different materials.
摘要:
A composite bone graft (1) for implantation in a patient, to methods of making, and using the composite bone graft along with methods for treating patients by implanting the composite bone graft at a site in a patient. The composite bone graft includes two or more connected, discrete, bone portions (2-4), and includes one or more bio-compatible connectors (7) which hold together the discrete bone portions (2-4) to form the composite bone graft (1). The composite bone graft (1) may include one or more textured bone surfaces (14b). The textured surface (14a, 14b) preferably includes a plurality of closely spaced protrusions, preferably closely spaced continuous protrusions. The composite bone graft (1) is useful for repairing bone defects caused by congenital anomaly, disease, or trauma in a patient, for example, for restoring vertical support of the anterior, and/or posterior column. Implantation of the composite bone graft results in improved graft stability, and osteo-induction ability, without a decrease in mechanical strength.
摘要:
An intraocular lens for providing a subject with vision at various distances includes an optic having a first surface with a first shape, an opposing second surface with a second shape, a multifocal refractive profile, and one or more diffractive portions. The optic may include at least one multifocal diffractive profile. In some embodiments, multifocal diffractive and the multifocal refractive profiles are disposed on different, distinct, or non-overlapping portions or apertures of the optic. Alternatively, portions of the multifocal diffractive profiles and the multifocal refractive profiles may overlap within a common aperture or zone of the optic.