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55 条记录 (耗时 0.031 秒)

    SOFT TISSUE REPAIR SYSTEM
    17.
    发明授权
    SOFT TISSUE REPAIR SYSTEM 有权
    系统用于回收软组织

    公开(公告)号：EP1257205B1

    公开(公告)日：2010-12-08

    申请号：EP01948931.9

    申请日：2001-02-07

    申请人： Omeros Corporation

    发明人： DEMOPULOS, Gregory, A. ,  REED, Scott, W. ,  BACHMAN, Alan, B. ,  KARL, Frederick, T. ,  ALLEN, William, J. ,  ADAMS, Leland, R. ,  THATCHER, G., Lawrence

    IPC分类号： A61B17/064 ,  A61B17/86 ,  A61B17/88

    CPC分类号： A61B17/064 ,  A61B17/00491 ,  A61B2017/00004 ,  A61B2017/0646 ,  A61B2017/0647

    摘要： A medical fastener (18), preferably bioabsorbable, is used for repairing torn soft tissue, particularly meniscal tissue (16). The fastener (18) can have an enlarged head (22) at the proximate end to engage meniscal tissue (16) adjacent to a tear (14), and a pointed distal tip (21) at the other end to ease insertion of the fastener (18) into the meniscus (16). The shank (20) of the fastener (18) bridges across the tear (14). Opposite ends of the shank (20) are secured in the meniscal tissue (16) by a medical adhesive, preferably bioabsorbable, and preferably at locations remote from the tear (14) so as not to interfere with healing of the tear (14). The fastener (18) can have a blind bore (24) opening through the head (22) of the fastener (18) and extending through the shank (20) to a location close to the tip (21) and generally radial holes (26) communicating between the bore (24) and the exterior of the shank (20). The medical adhesive can be injected through the bore (24) for passage outward through the holes (26).

    IRRIGATION SOLUTION AND METHOD FOR INHIBITION OF PAIN AND INFLAMMATION
    20.
    发明公开
    IRRIGATION SOLUTION AND METHOD FOR INHIBITION OF PAIN AND INFLAMMATION 有权
    冲洗溶液和用于抑制疼痛和炎症的方法

    公开(公告)号：EP1227807A2

    公开(公告)日：2002-08-07

    申请号：EP99956629.2

    申请日：1999-10-20

    申请人： Omeros Corporation

    发明人： DEMOPULOS, Gregory, A. ,  PALMER, Pamela, P. ,  HERZ, Jeffrey, M.

    IPC分类号： A61K31/18 ,  A61K31/415 ,  A61K31/495 ,  A61K31/55 ,  A61K31/535 ,  A61P23/02

    CPC分类号： A61K31/444 ,  A61K31/00 ,  A61K31/18 ,  A61K31/352 ,  A61K31/4164 ,  A61K31/4168 ,  A61K31/4174 ,  A61K31/439 ,  A61K31/4406 ,  A61K31/4427 ,  A61K31/4439 ,  A61K31/498 ,  A61K31/538 ,  A61K31/55 ,  A61K45/06 ,  A61K2300/00

    摘要： A method and solution for perioperatively inhibiting a variety of pain and inflammation processes at wounds from general surgical procedures including oral/dental procedures. The solution preferably includes at leat one α2-receptor agonist from the group consisting of clonidine; dexmedetomidine; oxymetazonline; (R)-(-)-3'-(2-amino-1-hydroxyethyl)-4'-fluoro-methanesulfoanilide; 2-[(5-methylbenz-1-ox-4-azin-6-yl)imino]imidazoline; AGN 191103; AGN 192172; 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-6-quinoxalinamine (UK14304); 5,6,7,8-tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepin-2-amine (BHT920); 6-ethyl-5,6,7,8-tetrahydro-4H-oxaazolo[4,5-d]azepin-2-amine; and 5,6-dihydroxyl-1,2,3,4-tetrahydro-1-naphyl-imidazoline, and optionally, additional multiple pain and inflammation inhibitory agents at dilute concentration like a serotonin2 antagonist, a serotonin3 antagonist, a histamine antagonist, a serotonin agonist, a cyclooxygenase inhibitor, a neurokinin1 antagonist, a neurokinin2 antagonist, a purinoceptor antagonist, an ATP-sensitive potassium channel opener, a calcium channel antagonist, a bradykinin1 antagonist, a bradykinin2 antagonist and a $(g)m-opioid agonist. The solution is applied by continous irrigation of a wound during a surgical procedure for preemptive inhibition of pain. The solution is applied b continuous irrigation of a wound during a surgical procedure for preemptive inhibition of pain.