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53 条记录 (耗时 0.026 秒)

    Polar lipid mixtures, their preparation and uses
    11.
    发明公开
    Polar lipid mixtures, their preparation and uses 审中-公开
    Polare Lipidmischungen，ihre Herstellung und Verwendungen

    公开(公告)号：EP2382872A1

    公开(公告)日：2011-11-02

    申请号：EP10185915.5

    申请日：2006-04-27

    申请人： Enzymotec Ltd.

    发明人： Shulman, Avidor ,  Zuabi, Rassan ,  Ben Dror, Gai ,  Twito, Yoni ,  Pelled, Dori ,  Herzog, Yael

    IPC分类号： A23L1/29 ,  A23L1/30 ,  A23J7/00 ,  A61P25/28 ,  C07F9/10

    CPC分类号： A23J7/00 ,  A23L33/115 ,  A23V2002/00 ,  A23V2250/185 ,  A23V2250/1852 ,  A23V2250/1848

    摘要： Disclosed herein are polar lipid mixtures, comprising glycerophospholipids such as phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylserine (PS) and phosphatidylinositol (PI), and sphingolipids such as sphyngomyelin (SM). Most importantly, the ratio of phospholipids in said mixture is comparable to that of HMF, and is represented by SM>PC>PE>PS>PI or SM=PC>PE>PS>PI. Processes for the preparation of said mixtures and uses thereof are also described herein.

    摘要翻译： 本文公开了包含甘油磷脂如磷脂酰胆碱（PC），磷脂酰乙醇胺（PE），磷脂酰丝氨酸（PS）和磷脂酰肌醇（PI）的脂质混合物，以及鞘脂如鞘氨醇（SM）。 最重要的是，所述混合物中磷脂的比例与HMF相当，由SM> PC> PE> PS> PI或SM = PC> PE> PS> PI表示。 本文还描述了制备所述混合物的方法及其用途。

    PROCESS FOR THE PRODUCTION OF PHOSPHOLIPIDS
    13.
    发明公开
    PROCESS FOR THE PRODUCTION OF PHOSPHOLIPIDS 有权
    生产磷脂的方法

    公开(公告)号：EP1412511A2

    公开(公告)日：2004-04-28

    申请号：EP02728001.5

    申请日：2002-05-02

    申请人： Enzymotec Ltd.

    发明人： BASHEER, Sobhi ,  ZUABI, Rassan ,  SHULMAN, Avidor ,  MAR-CHAIM, Neta

    IPC分类号： C12P9/00 ,  C07F9/10 ,  C12P7/62 ,  C12P13/00

    CPC分类号： C07F9/10 ,  C12P7/6481 ,  C12P9/00 ,  C12P13/001 ,  C12P13/06

    摘要： The present invention provides a new enzymatic process for preparing 1,2-diacylated phospholipids comprising the use of an enzyme preparation possessing phospholipase activity towards acylation at the sn-1 and sn-2 sites in a microaqueous reaction system. More particularly, the 1,2-diacyl-phospholipids produced according to the esterification/transesterification process of the present invention are obtainable in high yield and purity and carry identical desired carboxylic acid, preferably fatty acid, acyl groups at the sn-1 and sn-2 positions. The process involves esterification/transesterification (acylation) of a glycerophospholipid, preferably glycerophosphoryl choline (GPC) with a desired carboxylic acid, preferably fatty acid, or their derivatives in the presence of the above mentioned appropriate enzyme preparation. The process of the invention further relates to a process for the production of 1-acyl-2-lyso-glycerophospholipid, preferably 2-lyso-PC by reacting glycerophospholipid, preferably glycerophosphoryl choline (GPC) with a desired carboxylic acid, preferably fatty acid, or their derivatives in the presence of a sn-1 specific phospholipase (PLA1 or PLA1,2) and a solvent, in a microaqueous medium.

    摘要翻译： 本发明提供了一种用于制备1,2-二酰化磷脂的新的酶促方法，包括在微水相反应体系中使用具有磷脂酶活性的酶制剂，用于在sn-1和sn-2位点进行酰化。 更特别地，根据本发明的酯化/酯交换方法制备的1,2-二酰基 - 磷脂可以以高收率和纯度获得，并且在sn-1和sn上携带相同的期望的羧酸，优选脂肪酸，酰基 -2个职位。 该方法包括在上述合适的酶制剂存在下，将甘油磷脂，优选甘油磷酰胆碱（GPC）与期望的羧酸，优选脂肪酸或其衍生物进行酯化/酯交换（酰化）。 本发明的方法还涉及通过使甘油磷脂，优选甘油磷酰胆碱（GPC）与所需羧酸，优选脂肪酸反应来生产1-酰基-2-溶血甘油磷脂，优选2-溶血PC的方法， 或它们的衍生物在存在sn-1特异性磷脂酶（PLA1或PLA1,2）和溶剂的情况下在微水介质中进行。

    ENZYMATIC MODIFICATION OF STEROLS USING STEROL-SPECIFIC LIPASE
    20.
    发明公开
    ENZYMATIC MODIFICATION OF STEROLS USING STEROL-SPECIFIC LIPASE 审中-公开
    酶法变化固醇固醇使用特定的脂肪酶

    公开(公告)号：EP1268754A1

    公开(公告)日：2003-01-02

    申请号：EP01919737.5

    申请日：2001-04-03

    申请人： Enzymotec Ltd.

    发明人： BASHEER, Sobhi ,  PLAT, Dorit

    IPC分类号： C12N9/18 ,  C11C3/00 ,  A23D7/00 ,  A23D9/013 ,  A23L1/30 ,  A23C15/14 ,  C12N11/00 ,  A61K7/00

    CPC分类号： C12Y301/01003 ,  A23C15/145 ,  A23D7/011 ,  A23D9/013 ,  A23L33/11 ,  A61K8/63 ,  A61Q9/00 ,  C11C3/003

    摘要： The invention relates to a process for the selective alcoholysis of a free sterol, by contacting said free sterol with a fat-based product, optionally with the addition of carboxylic fatty acid(s) and/or ester derivative(s) thereof that are not derived from said fat-based product, in the presence of an immobilized lipase complex which may optionally be surfactant-coated, which complex possesses a high level of sterol-specific alcoholytic and/or esterfication activity and minimal acidolytic and transesterification activities. The fat-based product is a nutritional product or food, particularly butterfat, or a cosmetic or cosmetic or cosmetic-related product. The process may be used for preparing substantially cholesterol-free fat-based products, particularly products containing butterfat, by selectively esterfying any free cholesterol contained therein by the immobilized, preferably surfactant coated lipase. The invention also relates to a process for the in situ enrichment of a fat-based product with esterified phytosterol ester(s). In this process, the esterification of the phytosterol is simultaneously accompanied by esterification of any free cholesterol present in said fat-based product.