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公开(公告)号:EP3195884B1
公开(公告)日:2018-09-19
申请号:EP16168494.9
申请日:2016-05-05
发明人: SUN, Jie , CHEN, Fan , QIAO, Hongying , DING, Lingcui , MENG, Kai
CPC分类号: A61F2/0063 , A61F2210/0004 , A61L31/048 , A61L31/10 , A61L31/148 , C08L67/04 , C08L23/12
摘要: A repair material with multi-purpose for an abdominal wall hernia relates to a field of medical consumables, and includes an absorbable membrane which is made from a mixed solution of a PLCL and an MPEG-PLLA copolymer. In the MPEG-PLLA copolymer, a molecular weight of the MPEG is 2000-10000, and a molecular weight of the PLLA is 3000-8000. Compared with the PLCL, the repair material of the present invention significantly improves water absorption of the absorbable and healing effects, and a contact angle is greatly reduced. As a result, postoperative abdominal wall compliance is sufficient, which basically provides no discomfort. Therefore, compared with the PLCL, the present invention is more comfortable. In addition, the repair material of the present invention doesn't need to be heat-fitted, and polypropylene is completely fitted with the absorbable membrane, in which no obvious boundary face is observed through a microscope, and separation is never occurred.
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公开(公告)号:EP3030278B1
公开(公告)日:2018-09-19
申请号:EP13759403.2
申请日:2013-08-28
CPC分类号: A61L27/58 , A61F2/82 , A61L31/10 , A61L31/148
摘要: A stent having an inner surface and an outer surface, at least a portion of the outer surface of the stent comprising a dissolvable adhesive polymer or a degradable adhesive polymer disposed on at least a portion of the outer surface of the stent, the adhesive is activated by exposure to an aqueous environment, the dissolvable adhesive polymer dissolves over time in an aqueous environment, the dissolvable adhesive polymer or the degradable adhesive polymer has a surface tack of about 2 psi to about 14 psi.
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公开(公告)号:EP2668966B1
公开(公告)日:2018-09-12
申请号:EP12739295.9
申请日:2012-01-20
申请人: Olympus Corporation
发明人: TAMAI, Masato , SAKAMOTO, Takamitsu
CPC分类号: A61B17/866 , A61F2210/0004 , A61L27/047 , A61L27/306 , A61L27/58 , A61L31/022 , A61L31/082 , A61L31/148 , A61L2430/02
摘要: The present invention can suitably be used even in a site where hydrogen gas is metabolized slowly, such as the osseous tissue. Provided is a biodegradable implant (1) including a biodegradable magnesium member (2) formed of a magnesium alloy and coating layers (3 and 4) that coat the biodegradable magnesium member (2), thereby reducing the degradation rate thereof in a living organism. Also provided is a biodegradable implant fabrication method including a coating step of coating a surface of a biodegradable magnesium member formed of a magnesium alloy with a coating layer that reduces the degradation rate in a living organism.
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公开(公告)号:EP3366325A1
公开(公告)日:2018-08-29
申请号:EP16856622.2
申请日:2016-06-08
发明人: LIN, Wenjiao , QIN, Li , ZHANG, Deyuan , SUN, Hongtao , ZHANG, Gui
CPC分类号: A61L31/022 , A61L31/02 , A61L31/082 , A61L31/10 , A61L31/14 , A61L31/148 , A61L31/16
摘要: An absorbable iron-based alloy implantable medical device comprises an iron-based alloy substrate (11), a degradable polymer coating (16) disposed on the surface of the iron-based alloy substrate (11), and a corrosion inhibition layer (12) disposed on the surface of the iron-based alloy substrate (11). The corrosion inhibition layer (12) can delay early-stage corrosion of the iron-based alloy substrate (11), ensure mechanical performance of a medical device in the early stage of the implantation, prevent degradation of a polymer in the early stage of the implantation of the medical device, and reduce the usage of the degradable polymer, thereby reducing risks of inflammatory reactions.
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公开(公告)号:EP2707046B1
公开(公告)日:2018-08-29
申请号:EP12722605.8
申请日:2012-05-09
发明人: WANG, Yunbing , MA, Xiao
CPC分类号: A61L31/148 , A61L31/06 , A61L2430/00 , A61L2430/22 , B29C35/0288 , B29C35/0805 , B29C47/0004 , B29C47/0023 , B29C47/92 , B29C2035/0838 , B29C2947/92228 , B29C2947/92704 , B29K2067/046 , B29K2105/0002 , B29K2995/0088 , B29L2023/22 , B29L2031/7532 , C08L67/04
摘要: Methods of controlling the degradation profile of a biodegradable stent scaffolding are disclosed. Disclosed methods include controlling features of the degradation profile including the time to loss of radial strength and the degradation time of the stent.
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公开(公告)号:EP2763712B1
公开(公告)日:2018-08-15
申请号:EP12731258.5
申请日:2012-06-20
发明人: STANKUS, John , WANG, Yunbing , TROLLSAS, Mikael , HOSSAINY, Syed Faiyaz Ahmed , NGO, Michael H. , DAVALIAN, Dariush
CPC分类号: A61F2/915 , A61F2210/0004 , A61F2210/0057 , A61F2230/0013 , A61F2230/0054 , A61L31/041 , A61L31/129 , A61L31/141 , A61L31/148
摘要: Bioabsorbable scaffolds are disclosed with a rigid polymer component and a rubbery polymer component. The rubbery polymer component is miscible, partially miscible, or immiscible with the rigid polymer component.
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公开(公告)号:EP3345631A1
公开(公告)日:2018-07-11
申请号:EP18151265.8
申请日:2006-02-21
IPC分类号: A61L31/16 , A61L29/04 , A61L29/08 , A61L29/16 , A61L31/04 , A61K31/145 , A61K31/395 , A61K31/337 , A61L31/14 , A61L31/10 , A61L27/34 , A61L27/54
CPC分类号: A61L31/16 , A61K31/145 , A61K31/337 , A61K31/395 , A61L27/34 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/148 , A61L2300/204 , A61L2300/416 , A61L2300/426 , A61L2420/06
摘要: The invention provides a medical device comprising a hydrophobic analog of a medicament known to inhibit cell proliferation and migration. The invention also provides a method of treating a narrowing in a body passageway comprising placing an implantable medical device comprising a hydrophobic analog of a medicament known to inhibit cell proliferation and migration. The medicaments can be incorporated within or coated on the device. The invention further provides hydrophobic analogs of medicaments known to inhibit cell proliferation and migration.
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公开(公告)号:EP1702592B1
公开(公告)日:2018-07-11
申请号:EP06004321.3
申请日:2006-03-03
申请人: BIOTRONIK AG
发明人: Tittelbach, Michael
IPC分类号: A61F2/82
CPC分类号: A61F2/82 , A61F2002/826 , A61F2210/0004 , A61F2250/0067 , A61L31/022 , A61L31/148 , A61L31/16 , A61L2300/416
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公开(公告)号:EP3337423A1
公开(公告)日:2018-06-27
申请号:EP16837727.3
申请日:2016-08-17
发明人: MARTIN, Russell , REDDY, Sashank , SACKS, Justin , LI, Xiaowei , CHO, Brian, Honewee , MAO, Hai-quan
CPC分类号: A61L27/48 , A61F2/0063 , A61F2/12 , A61F2210/0061 , A61F2250/0067 , A61L27/3633 , A61L27/52 , A61L27/54 , A61L27/56 , A61L27/58 , A61L31/129 , A61L31/148 , A61L31/16 , A61L2300/64 , A61L2430/04 , A61L2430/34 , C08L5/08 , C08L89/00 , C08L67/04
摘要: The presently disclosed composition and methods are provided for a hydrogel or nanofiber-hydrogel composite integrated with a surgical scaffold or mesh. A surgical scaffold device comprised of laminar composite is disclosed for the purpose of reducing foreign body response, managing tissue-materials interface, and improving the integration of the surgical mesh with the surrounding tissue of a subject.
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公开(公告)号:EP2822504B1
公开(公告)日:2018-05-16
申请号:EP13757259.0
申请日:2013-03-07
发明人: COTTONE, Robert, J.
CPC分类号: A61F2/06 , A61F2/915 , A61F2002/91541 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575 , A61F2230/0054 , A61F2250/0098 , A61L31/06 , A61L31/148 , A61L31/16
摘要: Stents may comprise a bioabsorbable polymer and a plurality of circumferential elements. Circumferential elements that are adjacent to one another may form an adjacent pair that is connected by one or more first connection elements and one or more second connection elements. In some embodiments, the circumferential elements may be formed from undulations having a sinusoidal pattern. The first and second connection elements and portions of the circumferential elements may form a substantially helical pattern across the longitudinal axis of the stent. In one embodiment, the first connection element may include one or more radiopaque markers. In some embodiments, the second connection elements may be curvilinear and may become substantially linear after the expansion of the stent. Curvilinear second connection elements may facilitate the expansion of the stent radially while overall length of the stent remains substantially constant.
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