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26 条记录 (耗时 0.018 秒)

    Drug releasing coatings for medical devices
    14.
    发明公开
    Drug releasing coatings for medical devices 审中-公开
    用于医疗器械的药物释放涂层

    公开(公告)号：EP2500046A2

    公开(公告)日：2012-09-19

    申请号：EP11176688.7

    申请日：2008-05-16

    申请人： Lutonix, Inc.

    发明人： Wang, Lixiao

    IPC分类号： A61L29/16 ,  A61L31/16

    CPC分类号： A61L29/16 ,  A61K31/337 ,  A61K31/436 ,  A61K45/06 ,  A61L29/08 ,  A61L29/085 ,  A61L29/18 ,  A61L31/16 ,  A61L31/18 ,  A61L2300/216 ,  A61L2300/416 ,  A61L2300/428 ,  A61L2300/608 ,  A61L2300/802 ,  A61L2420/06 ,  A61L2420/08 ,  A61M25/10 ,  A61M2025/105 ,  A61M2210/1025 ,  A61K2300/00

    摘要： The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device.
    The layer contains a therapeutic agent and an additive. In certain embodiments, the additive has a hydrophilic part and a drug affinity part, wherein the drug affinity part is at least one of a hydrophobic part, a part that has an affinity to the therapeutic agent by hydrogen bonding, and a part that has an affinity to the therapeutic agent by van der Waals interactions. In embodiments, the additive is water-soluble. In further embodiments, the additive is at least one of a surfactant and a chemical compound, and the chemical compound has a molecular weight of from 80 to 750 or has more than four hydroxyl groups.

    摘要翻译： 本发明涉及用于将治疗剂递送至组织的医疗装置。 医疗装置具有覆盖医疗装置的外表面的层。 该层含有治疗剂和添加剂。 在某些实施方案中，添加剂具有亲水部分和药物亲和部分，其中药物亲和部分是疏水部分，通过氢键对治疗剂具有亲和性的部分，以及具有 范德华相互作用对治疗剂的亲和力。 在实施方案中，添加剂是水溶性的。 在另外的实施方案中，添加剂是表面活性剂和化学化合物中的至少一种，并且化学化合物具有80至750的分子量或具有多于四个羟基。

    Catheter
    16.
    发明公开
    Catheter 有权

    公开(公告)号：EP1129735A3

    公开(公告)日：2002-02-27

    申请号：EP01301892.4

    申请日：2001-03-01

    申请人： Meddis Limited

    发明人： Gough, Nicholas James

    IPC分类号： A61M1/00

    CPC分类号： A61M1/0047 ,  A61M16/0463 ,  A61M2205/6081 ,  A61M2210/1025

    摘要： A catheter (2) for removing fluid from a patient comprises a tubing (4) having a distal end (6) for insertion into the patient and a proximal end secured to a vacuum control (10) for connection to a vacuum source for effecting removal of the fluid. The vacuum control (10) comprises a first, colour-coded, opaque portion (12) that is gripped by the operator, whereby the degree of suction applied to the catheter tubing (4) from the vacuum source is manually controlled by occlusion of a vent (24) of the first portion (12). A second portion (14) of the vacuum control (10) extends from the first portion (12) and receives the catheter tubing (4). The second portion (14) is substantially transparent and defines an observation chamber to allow the operator to observe the material drawn from the patient.

    A PORTABLE SUCTION DEVICE
    17.
    发明授权
    A PORTABLE SUCTION DEVICE 审中-公开

    公开(公告)号：EP2919827B1

    公开(公告)日：2018-12-26

    申请号：EP13854647.8

    申请日：2013-11-13

    申请人： Construct Medical Pty Ltd

    发明人： ESNOUF, Philip, Stuart ,  AULD, David, John

    IPC分类号： A61M1/00

    CPC分类号： A61M1/0076 ,  A61M1/0001 ,  A61M1/0074 ,  A61M16/0463 ,  A61M2210/1025

    摘要： A portable suction device comprising: a gas inlet for receiving pressurized gas from an enclosed source; a gas flow path that extends from the gas inlet to an exhaust; a suction generator that has a suction inlet, the gas flow path extending through the suction generator, such that gas flow through the flow path generates a low pressure at the suction inlet; a collection container with a collection inlet and an outlet that is coupled to the suction inlet; a suction tube that has proximal and distal ends, the proximal end being connected to the collection inlet of the collection container; a valve for controlling gas flow through the flow path, the valve having a stem that is configured to pierce the source with movement of the valve from a closed position.

    LOCAL ADMINISTRATION OF DRUGS FOR THE TREATMENT OF ASTHMA
    18.
    发明公开
    LOCAL ADMINISTRATION OF DRUGS FOR THE TREATMENT OF ASTHMA 审中-公开

    公开(公告)号：EP3344325A1

    公开(公告)日：2018-07-11

    申请号：EP16842868.8

    申请日：2016-08-31

    申请人： Mercator Medsystems, Inc.

    发明人： STEIN, Emily ,  SEWARD, Kirk Patrick

    IPC分类号： A61M31/00 ,  A61B17/24 ,  A61M25/10

    CPC分类号： A61K38/57 ,  A61K31/573 ,  A61M25/0084 ,  A61M25/1002 ,  A61M2025/0087 ,  A61M2025/105 ,  A61M2025/1068 ,  A61M2025/1093 ,  A61M2037/0023 ,  A61M2210/1025

    摘要： Methods for treating inflammatory pulmonary diseases by administering to the patient an effective amount of one or more pharmaceutical agents are disclosed. The pharmaceutical agents administered can include antibiotics, steroids, NSAIDs, DMARDs, growth factor receptor inhibitors, PI3K inhibitors, neurotransmitter receptor inhibitors, or protease inhibitors. The dose administered is effective to suppress or prevent initiation, progression, or relapses of disease, including the progression of established disease. The pharmaceutical agent is administered to a patient determined to have the disease and at an amount effective to suppress or prevent activity of the disease. The pharmaceutical agent is administered using a transtracheal, transbronchial, or transvascular drug delivery catheter. The pharmaceutical agent can be administered to the patient's pulmonary tissue to suppress reactions in response to bronchial thermoplasty either before, during, or after bronchial thermoplasty.

    DEVICES AND METHODS FOR AIRWAY SUCTIONING
    19.
    发明公开
    DEVICES AND METHODS FOR AIRWAY SUCTIONING 审中-公开
    VORRICHTUNGEN UND VERFAHREN ZUR ATEMWEGSABSAUGUNG

    公开(公告)号：EP3068476A4

    公开(公告)日：2017-07-26

    申请号：EP14862586

    申请日：2014-11-05

    申请人： CIEL MEDICAL INC

    发明人： GARRETT MARY K ,  AZAGURY DAN E ,  HULME GARY B ,  JENKINSON RONAN L ,  JONES CHRIS ,  ROSE JACQUELINE

    IPC分类号： A61M16/04

    CPC分类号： A61M16/0463 ,  A61M1/008 ,  A61M16/0479 ,  A61M16/0488 ,  A61M16/0816 ,  A61M25/0102 ,  A61M25/0662 ,  A61M2025/0681 ,  A61M2025/0687 ,  A61M2210/1025

    摘要： Described here are devices, systems, and methods for positioning a suction catheter in the airway of a patient. The systems may comprise a suction catheter, a delivery device, and/or a stylet. The delivery device may comprise an elongate shaft, an atraumatic distal end, an elongate passageway, and a retention element configured to releasably couple to an endotracheal tube. The suction catheter may be positioned in the elongate passageway, and the delivery device may help advance the suction catheter into the airway of a patient. In some variations, the delivery device may comprise elements configured to release the suction catheter in the airway after positioning.

    摘要翻译： 这里描述的是用于将抽吸导管定位在患者的气道中的装置，系统和方法。 该系统可以包括抽吸导管，输送装置和/或探针。 递送装置可以包括细长轴，无创伤远端，细长通道和被配置为可释放地联接到气管内导管的保持元件。 抽吸导管可以定位在细长通道中，并且递送装置可以帮助将抽吸导管推进到患者的气道中。 在一些变型中，输送装置可以包括构造成在定位后在气道中释放抽吸导管的元件。

    APPARATUS FOR PUNCTURING BALLOON IN AIRWAY DILATION SHAFT
    20.
    发明公开
    APPARATUS FOR PUNCTURING BALLOON IN AIRWAY DILATION SHAFT 审中-公开
    用于在气道扩张轴中冲压气球的装置

    公开(公告)号：EP2968876A1

    公开(公告)日：2016-01-20

    申请号：EP14711049.8

    申请日：2014-02-24

    申请人： Acclarent, Inc.

    发明人： LAM, Sivette ,  WASICEK, Lawrence D. ,  MUNI, Ketan P. ,  WU, Show-Mean ,  NGUYEN, Andy ,  SHERMAN, Nicholas E. ,  CHAN, Randy S.

    IPC分类号： A61M29/02 ,  A61B17/24 ,  A61M16/04 ,  A61M25/10 ,  A61M25/01

    CPC分类号： A61B17/24 ,  A61M25/0102 ,  A61M25/10 ,  A61M25/1018 ,  A61M25/10184 ,  A61M29/02 ,  A61M2210/1025 ,  A61M2210/1028 ,  A61M2210/1032 ,  A61M2210/1035

    摘要： A dilation system includes a balloon catheter and a puncturing assembly. The balloon catheter includes a shaft, a dilator coupled to a distal end of the shaft, and a lumen extending through the shaft and the dilator. The dilator is expandable from a collapsed state to an expanded state. The puncturing assembly includes at least one cutting member. The puncturing assembly is positionable within the lumen of the balloon catheter or along an exterior of the shaft when the puncturing assembly is in a first position. The puncturing assembly transitions to a second position to puncture the lumen of the balloon catheter and/or to puncture the dilator, to thereby drain fluid from the dilator.

    摘要翻译： 扩张系统（8）包括气囊导管（10）和穿刺组件（100）。 气囊导管包括轴（12），联接到轴的远端的扩张器（18）以及延伸穿过轴和扩张器的腔。 扩张器可从塌陷状态扩张至扩张状态。 穿刺组件包括至少一个切割构件（124）。 当穿刺组件处于第一位置时，穿刺组件可定位在球囊导管的腔内或沿着轴的外部定位。 穿刺组件转换到第二位置以刺穿球囊导管的内腔和/或穿刺扩张器，从而从扩张器排出流体。