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公开(公告)号:EP1140280B1
公开(公告)日:2016-11-16
申请号:EP99961255.9
申请日:1999-12-22
申请人: Syneron Medical Ltd.
发明人: AVRAHAMI, Zohar
CPC分类号: A61N1/327 , A61N1/0476 , A61N1/0496 , A61N1/30 , A61N1/325 , Y10S977/775
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公开(公告)号:EP2992084A4
公开(公告)日:2016-10-05
申请号:EP14791537
申请日:2014-03-03
发明人: SKIBA JEFFRY , MAKIN INDER RAJ S
IPC分类号: A61F13/02
CPC分类号: A61N1/0468 , A61F13/00038 , A61F13/00051 , A61F13/00063 , A61F13/02 , A61F2013/0028 , A61G10/026 , A61M1/0088 , A61M35/00 , A61M2202/0208 , A61N1/0428 , A61N1/0464 , A61N1/0476 , A61N1/0492 , A61N1/205 , A61N1/30 , A61N1/325 , A61N1/326
摘要: A system for wound treatment includes adjunctive wound therapy devices and substrates comprising multiple first reservoirs and multiple second reservoirs. Selected ones of the multiple first reservoirs include a reducing agent, and first reservoir surfaces of selected ones of the multiple first reservoirs are proximate to a first substrate surface. Selected ones of the multiple second reservoirs include an oxidizing agent, and second reservoir surfaces of selected ones of the multiple second reservoirs are proximate to the first substrate surface.
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公开(公告)号:EP2949359A4
公开(公告)日:2016-09-14
申请号:EP13872485
申请日:2013-01-23
申请人: TERUMO CORP
发明人: NARIMATSU KIYOYUKI
CPC分类号: A61N1/08 , A61N1/0448 , A61N1/30 , A61N1/303
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公开(公告)号:EP3010582A4
公开(公告)日:2016-07-13
申请号:EP14814517
申请日:2014-06-23
CPC分类号: A61N1/30 , A61K38/185 , A61N1/0541 , A61N1/327
摘要: The present invention relates to improved methods for transfecting one or more cells within a target region with an agent by electroporation. The method comprises exposing one or more cells to the agent and to a close electric field created between an anode or anode array and a cathode or cathode array in the target region for sufficient time to allow at least some of the agent to enter said one or more cells.
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15.
公开(公告)号:EP2359897B1
公开(公告)日:2016-04-13
申请号:EP11162446.6
申请日:2005-04-29
申请人: Eyegate Pharma SAS
发明人: Roy, Pierre
CPC分类号: A61F9/0017 , A61F9/00 , A61F2250/0068 , A61N1/0412 , A61N1/30 , A61N1/303
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公开(公告)号:EP1183065B1
公开(公告)日:2016-03-23
申请号:EP00942692.5
申请日:2000-06-07
CPC分类号: B81C99/0085 , A61M5/1723 , A61M37/0015 , A61M2037/0023 , A61M2037/003 , A61M2037/0053 , A61M2037/0061 , A61N1/30 , B81B2201/055
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公开(公告)号:EP2991601A1
公开(公告)日:2016-03-09
申请号:EP14791276.0
申请日:2014-03-03
发明人: SKIBA, Jeffry
IPC分类号: A61F13/02
CPC分类号: A61N1/0468 , A61F13/00038 , A61F13/00051 , A61F13/00063 , A61F13/02 , A61F2013/0028 , A61G10/026 , A61M1/0088 , A61M35/00 , A61M2202/0208 , A61N1/0428 , A61N1/0464 , A61N1/0476 , A61N1/0492 , A61N1/205 , A61N1/30 , A61N1/325 , A61N1/326
摘要: A system for wound treatment includes adjunctive wound therapy devices and substrates comprising multiple first reservoirs and multiple second reservoirs. Selected ones of the multiple first reservoirs include a reducing agent, and first reservoir surfaces of selected ones of the multiple first reservoirs are proximate to a first substrate surface. Selected ones of the multiple second reservoirs include an oxidizing agent, and second reservoir surfaces of selected ones of the multiple second reservoirs are proximate to the first substrate surface.
摘要翻译: 用于伤口处理的系统包括辅助伤口治疗装置和包括多个第一储存器和多个第二储存器的基底。 多个第一储存器中的选定储存器包括还原剂,并且多个第一储存器中的选定储存器的第一储存器表面接近第一衬底表面。 多个第二储器中的选定的一个包括氧化剂,并且多个第二储器中选定的一些的第二储器表面靠近第一衬底表面。
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公开(公告)号:EP2812069A4
公开(公告)日:2016-03-09
申请号:EP13747205
申请日:2013-02-04
发明人: LUZON JOSEF , GUROVICH MARTIN
CPC分类号: A61N1/044 , A61M35/003 , A61M35/006 , A61M2037/0007 , A61M2210/04 , A61N1/0428 , A61N1/0472 , A61N1/0575 , A61N1/30 , A61N1/303 , A61N1/325
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19.
公开(公告)号:EP2968927A1
公开(公告)日:2016-01-20
申请号:EP14709119.3
申请日:2014-02-24
申请人: Acclarent, Inc.
发明人: KERMANI, Mahyar Z. , ANDREAS, Bernard H. , GIROTRA, Rohit , SALEKI, Mansour A. , BHAT, Nikhil D.
CPC分类号: A61N1/30 , A61F11/00 , A61F11/002 , A61N1/0428 , A61N1/0472 , A61N1/0526 , A61N1/303 , A61N1/306 , A61N1/325
摘要: Various systems and methods provide iontophoretic delivery of anesthesia at a patient's tympanic membrane. Some implementations provide channel switching enabling a single current sink to pull current through two electrodes in an alternating fashion based on clock pulses. The iontophoretic delivery of anesthesia may be driven by an AC modulated current. Some implementations provide for continuous flow of fresh iontophoresis fluid to the ear canal during iontophoresis. The fluid flows from a source reservoir into the cavity between the tympanic membrane and a plug, and then drains out of the cavity to a reservoir. An iontophoresis system may also detect capacitance between an anode electrode and an auxiliary electrode in a patient's ear canal, watching for reduced capacitance to indicate presence of a bubble in the iontophoresis fluid.
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公开(公告)号:EP2850061A4
公开(公告)日:2015-12-09
申请号:EP13758184
申请日:2013-03-02
IPC分类号: C07D209/30 , A61K31/404 , A61K31/428 , A61P31/00 , A61P33/00 , A61P35/00 , A61P43/00 , C07D209/10 , C07D277/68 , C07D293/10 , C07D403/06 , C07D417/06 , C08G61/12 , C08G67/00 , C09B23/02
CPC分类号: A61K41/0057 , A61K31/403 , A61K31/404 , A61K31/438 , A61K41/0071 , A61N1/30 , A61N5/062 , A61N5/10 , A61N2005/0659 , A61N2005/0663 , C07D209/04 , C07D209/08 , C07D209/10 , C07D209/18 , C07D209/24 , C07D209/58 , C07D209/60 , C07D277/62 , C07D277/64 , C07D293/12 , C07D401/02 , C07D403/06 , C07D403/14 , C07D417/06 , C07D471/10 , C07D487/22 , C09B23/086 , C09B23/105 , C09B47/00 , C09B62/00
摘要: Halo-organic heterocyclic compounds are described, which have the formulas Ring A is an aromatic ring bound to at least two halogen atoms, at least one of which is iodine or bromine. Also described are polymethine dyes based on these heterocyclic compounds, and dendrimeric compounds and conjugates of such polymethine dyes. The polymethine dyes are characterized by enhanced properties, e.g., brightness, photostability, sensitivity and/or selective affinity that make them useful to target cancer cells, pathogenic microorganisms, and/or other biological materials, in applications such as photodynamic therapy, photodynamic antimicrobial chemotherapy (PACT), cancer treatment, selective removal or attachment of biological materials, antimicrobial coating materials, and other diagnostic, theranostic, spectrum shifting, deposition/growth, and analytic applications.
摘要翻译: 描述了具有下式的卤代有机杂环化合物:环A是与至少两个卤素原子结合的芳环,其中至少一个是碘或溴。 还描述了基于这些杂环化合物的聚甲基染料,以及这些聚甲炔染料的树枝状大分子化合物和共轭物。 聚甲炔染料的特征在于在诸如光动力学治疗,光动力学抗微生物化学疗法的应用中增强的性质,例如亮度,光稳定性,敏感性和/或选择性亲和力,使其可用于靶向癌细胞,致病微生物和/或其他生物材料 (PACT),癌症治疗,选择性去除或附着生物材料,抗微生物涂层材料以及其他诊断,分析,频谱移位,沉积/生长和分析应用。
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