RATIOMETRIC TEST STRIP AND METHOD
    12.
    发明公开
    RATIOMETRIC TEST STRIP AND METHOD 审中-公开
    辐射测试条和无线电测过程

    公开(公告)号:EP1896843A4

    公开(公告)日:2009-03-18

    申请号:EP06773018

    申请日:2006-06-13

    IPC分类号: G01N31/22

    摘要: The invention generally relates to devices, systems and methods adapted for use by patients for monitoring their own dietary intake of sodium without any need of laboratory facilities or collection of blood samples. The systems utilize test strips for measuring the concentration of analytes in urine, specifically, chloride and creatinine. Urinary chloride concentrations, normalized by creatinine concentrations to reduce variability contributed mainly by changing states of hydration serve as a conveniently monitored surrogate for salt intake by subjects, especially patients with hypertension or congestive heart failure who must control their salt intake carefully.

    Dry analytical element for lipase measurement
    13.
    发明公开
    Dry analytical element for lipase measurement 有权
    Trockenes分析元素zurbauchspeicheldrüsen-lipasemessung

    公开(公告)号:EP2003450A1

    公开(公告)日:2008-12-17

    申请号:EP08010750.1

    申请日:2008-06-12

    IPC分类号: G01N33/52 C12Q1/44

    摘要: It is an object of the present invention to provide a dry analytical element for pancreatic lipase analysis having high selectivity with respect to pancreatic lipase, whose multianalyte correlation has been improved. The present invention provides a dry analytical element for measurement of pancreatic lipase contained in a body fluid, which comprises at least one development layer and/or reagent layer containing diglyceride or triglyceride of long-chain alkyl fatty acid having 12 to 22 carbon atoms, monoglyceride lipase, and a glycerine measurement reagent, wherein the development layer and/or the reagent layer comprise two or more types of anionic surfactants and at least one type of the anionic surfactant is alkylarylsulfonate.

    摘要翻译: 本发明的目的是提供一种用于胰脂肪酶分析的干燥分析元件,其具有相对于胰多糖分子相关性提高的胰脂肪酶的高选择性。 本发明提供了一种用于测量体液中所含的胰脂肪酶的干燥分析元件,其包含至少一个含有12-22个碳原子的长链烷基脂肪酸的甘油二酯或甘油三酸酯的显影层和/或试剂层,单酸甘油酯 脂肪酶和甘油测量试剂,其中显影层和/或试剂层包含两种或更多种类型的阴离子表面活性剂,并且至少一种类型的阴离子表面活性剂是烷基芳基磺酸盐。

    TEST STRIP FOR CREATININE DETERMINATION
    14.
    发明公开
    TEST STRIP FOR CREATININE DETERMINATION 有权
    试纸条肌酐

    公开(公告)号:EP1560027A4

    公开(公告)日:2008-09-10

    申请号:EP03754123

    申请日:2003-10-15

    申请人: ARKRAY INC

    发明人: KOSAKA HIDEKO

    IPC分类号: G01N21/78 G01N33/52 G01N33/70

    摘要: A novel test strip for the determination of creatinine which is produced by incorporating a compound represented by the general formula (1), a metal capable of reacting with the compound to form a color complex, and a buffer into a porous material. The quantity of creatinine can be determined by measuring optically the quantity of a color complex formed from the compound and the metal and determining the inhibition of color complex formation by creatinine on the basis of the quantity measured above. (1) In the general formula (1), R is H, SO3X, or COOX; R and R are each independently OH, SO3X, or COOX; R , R , R , and R are each independently H, OH, Cl, Br, I, NO2, NO, or CH3; and Xs in R , R , and R are each independently H, Na, K, or NH4.

    Verfahren zur Bestimmung eines Analyten mittels einer Extraktionsschicht
    16.
    发明公开
    Verfahren zur Bestimmung eines Analyten mittels einer Extraktionsschicht 有权
    一种用于通过提取层的手段确定分析物的方法

    公开(公告)号:EP1531331A3

    公开(公告)日:2006-11-02

    申请号:EP04025384.1

    申请日:2004-10-26

    IPC分类号: G01N33/52 G01N33/86 G01N33/72

    摘要: Gegenstand der Erfindung ist ein Verfahren zur Bestimmung eines Analyten in einer Flüssigkeitsprobe mittels eines Testsystems bestehend aus mindestens zwei Kompartimenten, wobei in einem ersten Kompartiment die zur Bestimmung des Analyten notwendigen Nachweisreaktionen durchgeführt werden und in einem zweiten Kompartiment eine analytische Bestimmung einer an den Nachweisreaktionen beteiligten und vom Analyten verschiedenen Substanz, der Indikatorsubstanz, erfolgt, dadurch gekennzeichnet, dass die beiden Kompartimente in einer Weise voneinander abgegrenzt sind, welche den Übertritt der Indikatorsubstanz in das zweite Kompartiment ermöglicht und welche den Übertritt von weiteren Substanzen, welche die analytische Bestimmung der Indikatorsubstanz im zweiten Kompartiment stören können, zumindest teilweise verhindern und dass im zweiten Kompartiment mindestens eine weitere Substanz in immobilisierter Form vorliegt, welche als Fängersubstanz eine selektive Anreicherung der Indikatorsubstanz im zweiten Kompartiment bewirkt. Weitere Gegenstände der Erfindung sind Testsysteme zur Durchführung solcher Verfahren und die Verwendung dieser Testsysteme zur erfindungsgemäßen Bestimmung von Analyten.

    Device and method for measuring HDL-cholesterol emplying precipitation on a solid-phase
    20.
    发明公开
    Device and method for measuring HDL-cholesterol emplying precipitation on a solid-phase 失效
    Vorrichtung und Verfahren zur Festphase-Präzipitationsbestimmungvon HDL-Cholesterin

    公开(公告)号:EP1028319A2

    公开(公告)日:2000-08-16

    申请号:EP00109181.8

    申请日:1991-07-15

    发明人: Jones, Ronald M.

    IPC分类号: G01N33/92 B01D39/00 B01D39/20

    摘要: An assay device (14) for measuring the concentration of a soluble analyte, such as HDL-associated cholesterol, in a fluid sample containing interfering compounds, such as LDL- or VLDL-associated cholesterol, which can be selectively precipitated. The device includes a sieving matrix (26) capable of separating soluble and precipitated material migrating through the matrix, and a reservoir (34) which holds a precipitating agent which is effective, within a given concentration range, to selectively precipitate the interfering compounds. The reservoir is designed to delay the release of agent, on contact with the fluid sample, to maintain the concentration of precipitating agent in contact with the fluid sample within the given concentration range. The device additionally includes an assay pad (64, 66, 68, 70) in which the soluble analyte present in the fluid sample can be assayed. A method of separating high-density lipoproteins (HDL) from low- and very-low-density lipoproteins (LDL and VLDL) employs a coated glass fiber matrix which inhibits binding of HDL as a blood fluid sample containing HDL and precipitated LDL and VLDL passes through the matrix.

    摘要翻译: 用于测量含有可被选择性沉淀的干扰化合物如LDL或VLDL相关胆固醇的流体样品中的可溶性分析物(例如HDL相关胆固醇)的浓度的测定装置(14)。 该装置包括能够分离通过基质迁移的可溶性和沉淀物质的筛分基质(26),和在给定浓度范围内保持有效的沉淀剂的储存器(34)以选择性地沉淀干扰化合物。 储存器旨在延迟试剂在与流体样品接触时的释放,以保持沉淀剂的浓度与给定浓度范围内的流体样品接触。 该装置还包括其中可以测定存在于流体样品中的可溶性分析物的测定垫(64,66,68,70)。 从低密度脂蛋白(HDL)和低密度脂蛋白(LDL和VLDL)分离高密度脂蛋白(HDL)的方法采用涂覆的玻璃纤维基质,其抑制HDL作为含有HDL和沉淀LDL和VLDL通过的血液样品的结合 通过矩阵。