摘要:
A diagnostic test element (110) for detecting an analyte in a sample (126) of a bodily fluid, in particular in whole blood, is proposed. The diagnostic test element (110) comprises at least one test field (116) with at least one detection reagent, wherein the detection reagent is adapted to go through at least one detectable change in the presence of the analyte, in particular an optical change. The test field (116) comprises at least one detection layer (118) that comprises the detection reagent, said layer comprising particles (137). In the process, at least 90% of all particles (137) of the detection layer (118) have an actual particle size of less than 10 micrometers.
摘要:
The invention generally relates to devices, systems and methods adapted for use by patients for monitoring their own dietary intake of sodium without any need of laboratory facilities or collection of blood samples. The systems utilize test strips for measuring the concentration of analytes in urine, specifically, chloride and creatinine. Urinary chloride concentrations, normalized by creatinine concentrations to reduce variability contributed mainly by changing states of hydration serve as a conveniently monitored surrogate for salt intake by subjects, especially patients with hypertension or congestive heart failure who must control their salt intake carefully.
摘要:
It is an object of the present invention to provide a dry analytical element for pancreatic lipase analysis having high selectivity with respect to pancreatic lipase, whose multianalyte correlation has been improved. The present invention provides a dry analytical element for measurement of pancreatic lipase contained in a body fluid, which comprises at least one development layer and/or reagent layer containing diglyceride or triglyceride of long-chain alkyl fatty acid having 12 to 22 carbon atoms, monoglyceride lipase, and a glycerine measurement reagent, wherein the development layer and/or the reagent layer comprise two or more types of anionic surfactants and at least one type of the anionic surfactant is alkylarylsulfonate.
摘要:
A novel test strip for the determination of creatinine which is produced by incorporating a compound represented by the general formula (1), a metal capable of reacting with the compound to form a color complex, and a buffer into a porous material. The quantity of creatinine can be determined by measuring optically the quantity of a color complex formed from the compound and the metal and determining the inhibition of color complex formation by creatinine on the basis of the quantity measured above. (1) In the general formula (1), R is H, SO3X, or COOX; R and R are each independently OH, SO3X, or COOX; R , R , R , and R are each independently H, OH, Cl, Br, I, NO2, NO, or CH3; and Xs in R , R , and R are each independently H, Na, K, or NH4.
摘要:
The subject invention provides devices and methods for the analysis of a body fluid. Embodiments include sensors that are sample-fillable by contacting a corner of the sensor to a sample.
摘要:
Gegenstand der Erfindung ist ein Verfahren zur Bestimmung eines Analyten in einer Flüssigkeitsprobe mittels eines Testsystems bestehend aus mindestens zwei Kompartimenten, wobei in einem ersten Kompartiment die zur Bestimmung des Analyten notwendigen Nachweisreaktionen durchgeführt werden und in einem zweiten Kompartiment eine analytische Bestimmung einer an den Nachweisreaktionen beteiligten und vom Analyten verschiedenen Substanz, der Indikatorsubstanz, erfolgt, dadurch gekennzeichnet, dass die beiden Kompartimente in einer Weise voneinander abgegrenzt sind, welche den Übertritt der Indikatorsubstanz in das zweite Kompartiment ermöglicht und welche den Übertritt von weiteren Substanzen, welche die analytische Bestimmung der Indikatorsubstanz im zweiten Kompartiment stören können, zumindest teilweise verhindern und dass im zweiten Kompartiment mindestens eine weitere Substanz in immobilisierter Form vorliegt, welche als Fängersubstanz eine selektive Anreicherung der Indikatorsubstanz im zweiten Kompartiment bewirkt. Weitere Gegenstände der Erfindung sind Testsysteme zur Durchführung solcher Verfahren und die Verwendung dieser Testsysteme zur erfindungsgemäßen Bestimmung von Analyten.
摘要:
An assay device (14) for measuring the concentration of a soluble analyte, such as HDL-associated cholesterol, in a fluid sample containing interfering compounds, such as LDL- or VLDL-associated cholesterol, which can be selectively precipitated. The device includes a sieving matrix (26) capable of separating soluble and precipitated material migrating through the matrix, and a reservoir (34) which holds a precipitating agent which is effective, within a given concentration range, to selectively precipitate the interfering compounds. The reservoir is designed to delay the release of agent, on contact with the fluid sample, to maintain the concentration of precipitating agent in contact with the fluid sample within the given concentration range. The device additionally includes an assay pad (64, 66, 68, 70) in which the soluble analyte present in the fluid sample can be assayed. A method of separating high-density lipoproteins (HDL) from low- and very-low-density lipoproteins (LDL and VLDL) employs a coated glass fiber matrix which inhibits binding of HDL as a blood fluid sample containing HDL and precipitated LDL and VLDL passes through the matrix.