3-CYANO-2,4,5-TRIFLUOR-BENZOYLFLUORID UND ZWISCHENPRODUKTE ZU SEINER HERSTELLUNG
    12.
    发明公开
    3-CYANO-2,4,5-TRIFLUOR-BENZOYLFLUORID UND ZWISCHENPRODUKTE ZU SEINER HERSTELLUNG 失效
    3-氰基2,4,5-三氟苯甲酰及其生产中间产品

    公开(公告)号:EP0977729A1

    公开(公告)日:2000-02-09

    申请号:EP98919266.1

    申请日:1998-04-14

    申请人: BAYER AG

    摘要: The invention relates to 3-cyano-2,4,5-trifluoro-benzoyl fluoride and intermediate products for the production thereof and a method for the production of 3-cyano-2,4,5-trifluoro-benzoyl fluoride starting from 5-fluoro-1,3-xylol (VIII), which is chlorinated twice in the presence of a catalyst with ionic conditions in the nucleus to obtain 2,4-dichloro-5-fluoro-1,3-dymethylbenzol (VII), which is then chlorinated with radical conditions in the side chains to obtain 2,4-dichloro-5-fluoro-3-dichloromethyl-1-trichloromethyl benzol (VI), which is subsequently saponified by the optionally isolatable 2,4-dichloro-5-fluoro-3-dichloromethyl benzoic acid (V) to obtain 2,4-dichloro-5-fluoro-3-formyl-benzoic acid (IV) whose aldehyde group is converted to 2,4-dichloro-5-fluoro-3-N-hydroxyiminomethyl-benzoic acid (III), whereupon water is eliminated using an acid chloride while at the same time converting the carboxyl group into a chlorocarbonyl group to obtain nitrile 2,4-dichloro-3-cyano-5-fluoro-benzoyl-chloride (II), which is finally subjected to a fluorine/chlorine exchange.