公开(公告)号：EP1252124B1

公开(公告)日：2004-03-31

申请号：EP00976090.1

申请日：2000-11-03

申请人： Pohjola, Pekka

发明人： Pohjola, Pekka

IPC分类号： C05F17/00 ,  C05F9/04 ,  C12N1/38

CPC分类号： C05F17/0036 ,  Y02P20/145 ,  Y02W30/43

摘要： The invention relates to a compost accelerator mixture which comprises a liquid part and optionally a solid part, the liquid part being a water solution that comprises at least sodium gluconate, ferrous ions Fe and manganese ions Mn , and as an optional solid part soil matter as well as optionally one or more different inorganic ingredients.

公开(公告)号：EP1074619A3

公开(公告)日：2003-05-21

申请号：EP00660130.6

申请日：2000-07-28

申请人： Panula, Pertii Aarre Juhani ,  Brandt, Annika ,  Westerlund, Johanna

发明人： Panula, Pertii Aarre Juhani ,  Brandt, Annika ,  Westerlund, Johanna

IPC分类号： C12N15/12 ,  C07K14/47 ,  A01K67/027 ,  A61K48/00 ,  C12Q1/68

CPC分类号： C07K14/4705 ,  A01K2217/05 ,  A61K38/00 ,  A61K48/00 ,  C07K14/47 ,  C07K2319/00

摘要： The present invention relates to isolating, sequencing and cloning of the 5'-flanking region of neuropeptide FF (NPFF) promoter. The characterized neuropeptide FF (NPFF) promoter is useful in gene therapy and in DNA analyses, and in production of gene-modified animals.

公开(公告)号：EP1198477A1

公开(公告)日：2002-04-24

申请号：EP00951554.5

申请日：2000-08-03

申请人： Oy Juvantia Pharma Ltd

发明人： PANULA, Pertti, Aarre, Juhani ,  PERTOVAARA, Antti ,  KALSO, Eija ,  KORPI, Esa

IPC分类号： C07K14/575 ,  C07K14/72 ,  A61K38/22 ,  A61P5/00 ,  A61P25/04 ,  G01N33/68

CPC分类号： C07K14/575 ,  A61K38/00 ,  G01N33/6893 ,  G01N2333/4703 ,  G01N2800/2842 ,  G01N2800/321

摘要： The present invention relates to a method for regulating autonomic functions, such as blood pressure, and further to a method for treating pain by prolactin-releasing peptide (PrRP) or through its receptor. This peptide regulates blood pressure and pain mechanisms, and is expressed in complementary areas with neuropeptide FF (NPFF). Specific antisera developed against the N- and/or C-terminal domains of PrRP may be used for diagnostics.

公开(公告)号：EP0995758A1

公开(公告)日：2000-04-26

申请号：EP98924597.2

申请日：1998-06-12

申请人： ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI

发明人： TAKEUCHI, Tomio, New Fuji Mansion 701 ,  UMEZAWA, Kazuo ,  KONDO, Shinichi, Royal Heights Minami-Rokugo 608 ,  IKEDA, Yoko, Crescent Ikejiri Ohashi 502 ,  NAGANAWA, Hiroshi ,  HAMADA, Masa

IPC分类号： C07K7/06 ,  C12P21/04 ,  C12N1/20 ,  A61K38/12

CPC分类号： C12R1/465 ,  A61K38/00 ,  C07K7/06

摘要： As novel substances having an activity of inducing an apoptosis even on the apoptosis-resistant cancer cells, there are obtained polyoxypeptin and deoxypolyoxypeptin represented by the following general formula (I)
wherein R denotes a hydroxyl group for polyoxypeptin, or R denotes a hydrogen atom for deoxypolyoxypeptin, by cultivation of Streptomyces sp. MK498-98F14 strain. Polyoxypeptin and deoxypolyoxypeptin are physiologically active substances which have an activity of inducing apoptosis on a human pancreatic adenocarcinoma cell, AsPC-1 cell.

摘要翻译： 作为具有诱导细胞凋亡抗性的癌细胞的细胞凋亡的活性的新物质，可以举出以下通式（I）表示的多羟脯氨酸和脱氧多肽，其中R表示多羟脯氨酸的羟基，R表示 氢原子用于脱氧脱氧蛋白，通过培养链霉菌 MK498-98F14菌株。 多氧蛋白和脱氧多肽蛋白是具有诱导人胰腺癌细胞AsPC-1细胞凋亡的生理活性物质。

公开(公告)号：EP0782487B1

公开(公告)日：1999-09-01

申请号：EP95930559.0

申请日：1995-09-20

申请人： AKTIEBOLAGET ELECTROLUX

发明人： NYRHILÄ, Olli, Juhani

IPC分类号： B22F3/105 ,  C22C1/04

CPC分类号： B22F3/1055 ,  B22F3/1007 ,  B22F2201/40 ,  B22F2998/00 ,  B22F2999/00 ,  B33Y10/00 ,  B33Y50/02 ,  B33Y70/00 ,  Y02P10/295 ,  B22F1/0003

摘要： PCT No. PCT/FI95/00514 Sec. 371 Date Mar. 21, 1997 Sec. 102(e) Date Mar. 21, 1997 PCT Filed Sep. 20, 1995 PCT Pub. No. WO96/09132 PCT Pub. Date Mar. 28, 1996The invention relates to a method for the fabrication of dimensionally accurate metal pieces by sintering a material which, before the sintering, consists of a blend of three pulverous ingredients, of which the first ingredient is in the main an iron-group metal, the second ingredient is in the main copper and phosphorus, and the third ingredient is an alloy of copper and some other metal. The shape of the piece is produced by layer-by-layer freeform selected area laser sintering, wherein a layer of the said powder blend is spread on a base, those regions of the layer which correspond to this cross-sectional surface of the piece are heated by a laser beam to the sintering temperature. Thereafter further successive powder layers are spread one on top of another, and in each layer in turn those areas which correspond to the cross-sectional surface of the piece in that layer are laser sintered. The sintering takes place in a gas atmosphere which contains a chemical compound of some iron-group metal, the compound decomposing at the sintering temperature, in which case the iron-group metal will deposit into those cross-sectional areas of the piece being sintered at a given time.

摘要翻译： PCT No.PCT / FI95 / 00514 Sec。 371日期1997年3月21日 102（e）1997年3月21日PCT PCT 1995年9月20日PCT公布。 出版物WO96 / 09132 日期：1996年3月28日本发明涉及通过烧结材料制造尺寸精确的金属片的方法，该材料在烧结之前由三种粉末成分的混合物组成，其中第一成分主要为铁 - 组金属，第二成分是主要的铜和磷，第三成分是铜和一些其他金属的合金。 该片的形状通过逐层自由选择区域激光烧结制造，其中所述粉末混合物的一层铺展在基底上，对应于该片的该横截面的那些区域是 通过激光束加热至烧结温度。 此后，另外连续的粉末层一个在另一个的顶部上扩展，并且在每个层中，与该层中的该片的横截面相对应的区域被激光烧结。 烧结发生在含有一些铁族金属的化合物的气体气氛中，该化合物在烧结温度下分解，在这种情况下，铁族金属将沉积在待烧结件的那些截面区域中 给定的时间

公开(公告)号：EP1546195B1

公开(公告)日：2007-10-31

申请号：EP03792443.8

申请日：2003-08-22

申请人： Jyväskylän Yliopisto

发明人： KULOMAA, Markku, Sakari ,  NORDLUND, Henri, Rainer ,  LAITINEN, Olli-Heikki ,  HYTÖNEN, Vesa

IPC分类号： C07K14/465

CPC分类号： C07K14/465

摘要： The present invention relates to new mutants of biotin binding proteins with improved properties, e.g., thermally stabilized compared to wild type proteins. Proteins, which bind biotin include chicken avidin and bacterial streptavidin, other poultry avidins, such as avidin proteins isolated from the duck, goose, ostrich and turkey, and chicken avidin-related proteins (AVRs).

公开(公告)号：EP1660647A1

公开(公告)日：2006-05-31

申请号：EP04767041.9

申请日：2004-09-13

申请人： VALTION TEKNILLINEN TUTKIMUSKESKUS

发明人： VERHO, Ritva ,  RICHARD, Peter ,  PENTTILÄ, Merja

IPC分类号： C12N9/04 ,  C12P7/00

CPC分类号： C12N9/0006

摘要： The invention is directed to an isolated DNA molecule which comprises a gene encoding an enzyme protein which has an NADH dependent L-xylulose reductase activity. The DNA sequence encoding the enzyme protein was identified. The invention is further directed to a microorganism transformed with said DNA molecule of the invention, as well as to the NADH dependent L-xylulose reductase. The invention can be utilised for the conversion of biomaterial, e.g. industrial waste material, containing carbohydrates to useful end products.

公开(公告)号：EP1440145A1

公开(公告)日：2004-07-28

申请号：EP02772434.3

申请日：2002-10-29

申请人： VALTION TEKNILLINEN TUTKIMUSKESKUS

发明人： RICHARD, Peter ,  VERHO, Ritva ,  LONDESBOROUGH, John ,  PENTTILÄ, Merja

IPC分类号： C12N1/19 ,  C12P7/06 ,  C12P7/10 ,  C12P7/18

CPC分类号： C12N9/0008 ,  Y02E50/17

摘要： The present invention relates to fungal microorganism having an increased ability to carry out biotechnological process(es). In particular, the invention relates to improving the regeneration of redox cofactors in biotechnological processes where useful products are produced from biomass containing pentoses. According to the invention, the microorganism is transformed with a DNA sequence encoding an NADP linked glyceraldehyde 3-phosphate dehydrogenase. The invention can be used to provide useful products for mankind from biological materials, including e.g. agricultural and forestry products, municipal waste. Examples of such useful products are ethanol, lactic acid, polyhydroxyalkanoates, amino acids, fats, vitamins, nucleotides and a wide variety of enzymes and pharmaceuticals.

公开(公告)号：EP1252124A1

公开(公告)日：2002-10-30

申请号：EP00976090.1

申请日：2000-11-03

申请人： Pohjola, Pekka

发明人： Pohjola, Pekka

IPC分类号： C05F17/00 ,  C05F9/04 ,  C12N1/38

CPC分类号： C05F17/0036 ,  Y02P20/145 ,  Y02W30/43

摘要： The invention relates to a compost accelerator mixture which comprises a liquid part and optionally a solid part, the liquid part being a water solution that comprises at least sodium gluconate, ferrous ions Fe2+ and manganese ions Mn2+, and as an optional solid part soil matter as well as optionally one or more different inorganic ingredients.

公开(公告)号：EP1126818A1

公开(公告)日：2001-08-29

申请号：EP99956042.8

申请日：1999-11-05

申请人： Toporiina OY

发明人： ÖVERMARK-LEHTO, Heleena

IPC分类号： A61K7/09 ,  A45D7/06

CPC分类号： A45D7/06

摘要： The invention relates to a method for performing a hair permanent treatment using a substance soaked into a carrier material and acting chemically on the hair, such as a reducing agent, and heating elements on rolled-up strands of hair. The method comprises steps for: a) rolling up merely a strand of hair; b) placing a flexible carrier material, into which the active agent has been soaked, on the roll in one or more layers; c) placing a heating element on the carrier material and the roll; d) allowing heat to act over a predetermined period; and e) fixing and trimming in a manner known per se.