公开(公告)号：EP3983008A1

公开(公告)日：2022-04-20

申请号：EP20823678.6

申请日：2020-06-11

申请人： Iogenetics, LLC.

发明人： HOMAN, Jane ,  BREMEL, Robert, D.

IPC分类号： A61K39/00

公开(公告)号：EP3166631A4

公开(公告)日：2018-03-21

申请号：EP15819480

申请日：2015-07-10

申请人： IOGENETICS LLC

发明人： BREMEL ROBERT D ,  HOMAN JANE

IPC分类号： A61K39/00 ,  A61K38/00 ,  A61K38/08 ,  A61K39/38 ,  C07K16/00 ,  C40B30/04 ,  C40B30/10 ,  C40B50/02

CPC分类号： C07K16/00 ,  C07K2317/12 ,  C07K2317/20 ,  C07K2317/21 ,  C07K2317/56 ,  C07K2317/94

摘要： The present invention provides a means to prepare a product from domestic animal milk, blood or eggs which comprises an array of T-cell exposed motifs similar in identity, distribution and concentration to those found in human immunoglobulin variable regions and to prepare and apply the product as an immune modulating agent for administration either as a nutritional supplement or as a pharmaceutical product.

公开(公告)号：EP3008204A2

公开(公告)日：2016-04-20

申请号：EP14810932.5

申请日：2014-06-09

申请人： Iogenetics, LLC.

发明人： BREMEL, Robert D.

IPC分类号： C12Q1/37 ,  G01N33/48 ,  C40B50/02

CPC分类号： G06F19/18 ,  G06N3/0472 ,  G06N3/08

摘要： The present invention provides a bioinformatic methodology for prediction of peptidase cleavage sites based on principal component analysis and based on training sets obtained by experimental protein cleavage. This invention is not limited to training sets derived from CSL approaches, nor to any other experimental determination of cleavage site. Undoubtedly there will be new approaches to developed for experimental measurement of cleavage sites and these too may be the source of training sources for the present invention.

公开(公告)号：EP2771349A2

公开(公告)日：2014-09-03

申请号：EP12831761.7

申请日：2012-09-13

申请人： Iogenetics, LLC.

发明人： BREMEL, Robert D. ,  HOMAN, Jane

IPC分类号： C07K1/00 ,  C07K5/00 ,  C07K14/00 ,  G01N33/53

CPC分类号： A61K39/00 ,  A61K39/0007 ,  A61K39/0008 ,  A61K39/04 ,  A61K39/08 ,  A61K39/085 ,  A61K39/092 ,  A61K39/12 ,  A61K39/145 ,  A61K39/15 ,  A61K39/21 ,  A61K39/285 ,  A61K2039/55572 ,  C12N2710/24034 ,  C12N2720/12334 ,  C12N2740/14034 ,  C12N2760/16134 ,  G06F19/16

摘要： This invention relates to the identification of peptide binding to ligands, and in particular to identification of epitopes expressed by microorganisms and by mammalian cells. The present invention provides polypeptides comprising the epitopes, and vaccines, antibodies and diagnostic products that utilize or are developed using the epitopes.

公开(公告)号：EP2381788A4

公开(公告)日：2013-01-02

申请号：EP10732041

申请日：2010-01-13

申请人： IOGENETICS LLC ,  UNIV ARIZONA STATE

发明人： IMBODEN MICHAEL ,  RIGGS MICHAEL ,  SCHAEFER DEBORAH A ,  HOMAN JANE

IPC分类号： A01N63/02 ,  A01N63/00 ,  A01P1/00 ,  A01P3/00 ,  A61K38/16 ,  A61K39/44 ,  C07K16/00 ,  C07K19/00 ,  C12N15/62 ,  C12N15/867

CPC分类号： C07K16/20 ,  A01K2217/052 ,  A01K2217/206 ,  A01K2227/101 ,  A01K2267/01 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/76 ,  C07K2319/00 ,  C07K2319/01 ,  C07K2319/035 ,  C12N2740/13043

摘要： The present invention relates to fusion proteins comprising a microorganism targeting molecule (e.g., immunoglobulin) and a biocide. The present invention also relates to therapeutic and prophylactic methods of using a fusion protein comprising a microorganism targeting molecule and a biocide in diverse fields.