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公开(公告)号:EP2334331A1
公开(公告)日:2011-06-22
申请号:EP09793181.0
申请日:2009-09-30
发明人: SIEBEL, Christian, W. , WU, Yan
IPC分类号: A61K39/395 , A61P35/00 , C07K16/28
CPC分类号: C07K16/28 , A61K2039/505 , C07K16/30 , C07K16/3053 , C07K2317/21 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92 , C07K2319/00
摘要: The invention provides anti-Notch antibodies, and in particular, antibodies that bind Notch2 NRR, and methods of using the same.
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公开(公告)号:EP2200700A1
公开(公告)日:2010-06-30
申请号:EP08834260.5
申请日:2008-09-25
申请人: Genentech, Inc.
发明人: LIANG, Wei-Ching , PLOWMAN, Gregory D. , WU, Yan , YE, Weilan
CPC分类号: C07K16/2842 , A61K2039/505 , A61K2039/507 , C07K2317/24 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要: The present invention relates to the use of VEGF antagonists and a novel anti-α5β1 antibody for treating cancer and inhibiting angiogenesis and/or vascular permability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to compositions and kits comprising novel anti-α5β1 antibodies and methods of making and using them.
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23.ANTI-EPHRINB2 ANTIBOIES AND METHODS USING SAME 有权
标题翻译: ANTI-EPHRINB2-ANTIKÖRPERSOWIE VERFAHREN ZU IHRER VERWENDUNG公开(公告)号:EP1976884A2
公开(公告)日:2008-10-08
申请号:EP07797087.9
申请日:2007-01-19
申请人: Genentech, Inc.
发明人: YAN, Minhong , WU, Yan
IPC分类号: C07K16/28
CPC分类号: C07K16/28 , A61K2039/505 , C07K16/18 , C07K16/22 , C07K16/2866 , C07K2317/24 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要: The invention provides anti-EphrinB2 antibodies, and compositions comprising and methods of using these antibodies.
摘要翻译: 本发明提供了抗EphrinB2抗体,组合物和使用这些抗体的方法。
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公开(公告)号:EP4204806A1
公开(公告)日:2023-07-05
申请号:EP21790276.6
申请日:2021-08-31
申请人: GENENTECH, INC.
发明人: LIANG, Wei-Ching , LIN, WeiYu , WU, Yan
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公开(公告)号:EP3594228A1
公开(公告)日:2020-01-15
申请号:EP19175735.0
申请日:2004-06-02
申请人: GENENTECH, INC.
发明人: WU, Yan , LEE, James , HASS, Phillip , GURNEY, Austin , ARNOTT, David
摘要: The present invention is directed to a novel naturally occurring human cytokine that is comprised of a heterodimer of interleukin-17 and interleukin-17F designated herein as interleukin 17A/F (IL-17A/F). Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterolgous polypeptide sequences, specific antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.
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公开(公告)号:EP2970474A1
公开(公告)日:2016-01-20
申请号:EP14717318.1
申请日:2014-03-13
申请人: Genentech, Inc.
发明人: LEONG, Steven R. , POLSON, Andrew , POLAKIS, Paul , WU, Yan , LIANG, Wei-Ching , FIRESTEIN, Ron
IPC分类号: C07K16/28 , A61K47/48 , A61P35/00 , A61K39/395
CPC分类号: C07K16/2827 , A61K38/08 , A61K39/39558 , A61K47/65 , A61K47/6801 , A61K47/6809 , A61K47/6849 , A61K47/6855 , A61K51/1027 , A61K51/1051 , A61K2039/505 , C07K16/3015 , C07K2317/24 , C07K2317/33 , C07K2317/56 , C07K2317/73 , C07K2317/77 , C07K2317/92 , G01N33/56972
摘要: The disclosure provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
摘要翻译: 本公开提供抗B7-H4抗体和免疫缀合物及其使用方法。
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公开(公告)号:EP2200700B1
公开(公告)日:2016-01-13
申请号:EP08834260.5
申请日:2008-09-25
申请人: Genentech, Inc.
发明人: LIANG, Wei-Ching , PLOWMAN, Gregory D. , WU, Yan , YE, Weilan
CPC分类号: C07K16/2842 , A61K2039/505 , A61K2039/507 , C07K2317/24 , C07K2317/565 , C07K2317/76 , C07K2317/92
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28.
公开(公告)号:EP2804629A1
公开(公告)日:2014-11-26
申请号:EP13701352.0
申请日:2013-01-18
发明人: YE, Weilan , BURTON, Jeremy Bryant , WU, Yan , CHIU, Cecilia
IPC分类号: A61K39/395 , G01N33/50
CPC分类号: C07K16/28 , A61K39/395 , A61K47/6849 , A61K2039/505 , A61P9/10 , A61P27/02 , C07H21/04 , C07K2317/21 , C07K2317/24 , C07K2317/56 , C07K2317/567 , C07K2317/75 , C07K2317/92
摘要: The invention provides anti-LRP5 antibodies and methods of making and using the same.
摘要翻译: 本发明提供抗LRP5抗体及其制备和使用方法。
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公开(公告)号:EP1973950B1
公开(公告)日:2014-09-17
申请号:EP07797067.1
申请日:2007-01-04
申请人: Genentech, Inc.
发明人: WU, Yan , YAN, Minhong
IPC分类号: C07K16/28 , C12N5/10 , G01N33/53 , A61K39/395 , A61P35/00 , C07K16/30 , C12N15/13 , C12N15/63
CPC分类号: C07K16/2866 , A61K39/0011 , A61K2039/505 , C07K16/30 , C07K2317/33 , C07K2317/55 , C07K2317/76 , C07K2317/92
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公开(公告)号:EP1996625B1
公开(公告)日:2011-09-07
申请号:EP07758732.7
申请日:2007-03-16
申请人: Genentech, Inc.
发明人: LIANG, Wei-ching , SAKANAKA, Chie , WU, Yan
IPC分类号: C07K16/30 , C07K16/00 , A61P35/00 , A61K47/48 , A61K39/395 , C12N15/13 , C12N15/63 , C12N5/00
CPC分类号: A61K47/48638 , A61K47/6811 , A61K47/6851 , A61K47/6889 , A61K51/1045 , A61K2039/505 , C07K16/005 , C07K16/30 , C07K16/3069 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92 , C12N9/96
摘要: Anti-TAT226 antibodies and immunoconjugates thereof are provided. Methods of using anti-TAT226 antibodies and immunoconjugates thereof are provided.
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