公开(公告)号：EP1717306B1

公开(公告)日：2008-05-07

申请号：EP06008246.8

申请日：2006-04-21

申请人： Wallin, Hartmut

发明人： Wallin, Hartmut

IPC分类号： C12M1/113

CPC分类号： C12P5/023 ,  C12M21/04 ,  C12M21/16 ,  C12M29/02 ,  C12M33/14 ,  C12M33/20 ,  C12M41/18 ,  Y02E50/343

公开(公告)号：EP1648999A4

公开(公告)日：2006-09-06

申请号：EP04777155

申请日：2004-06-25

申请人： MACROPORE BIOSURGERY INC

发明人： HEDRICK MARC H ,  FRASER JOHN K ,  SCHULZKI MICHAEL J ,  BYRNES BOBBY ,  CARISON GRACE

IPC分类号： C12N5/00 ,  C12N20060101

CPC分类号： B04B5/0442 ,  A61K35/28 ,  B04B5/0407 ,  B04B2005/0471 ,  C12M33/14 ,  C12M45/00

摘要： Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and/or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject.

摘要翻译： 系统和方法被描述并用于从多种组织的分离细胞。 特别地，自动化系统和方法被描述并分离可再生细胞，E. G.，干细胞和/或祖细胞，从脂肪组织。 描述的系统和方法提供分离和浓缩适于再输注到受试者的再生细胞的快速和可靠的方法。

公开(公告)号：EP1681274A2

公开(公告)日：2006-07-19

申请号：EP06075081.7

申请日：2006-01-12

申请人： Orgaworld B.V.

发明人： Kaskens, Henricus Joseph Marie ,  Van den Boomen, Henricus Nicolaas Cornelis

IPC分类号： C02F11/04 ,  C12M1/18

CPC分类号： C05F17/02 ,  B09B3/00 ,  C05F17/027 ,  C12M21/04 ,  C12M21/16 ,  C12M29/02 ,  C12M29/24 ,  C12M33/14 ,  Y02E50/343 ,  Y02P20/145 ,  Y02W30/43 ,  Y02W30/47

摘要： A device (1) and a method for carrying out a fermentation process in a reactor (2), which reactor (2) comprises a liquid-permeable floor (3), two substantially parallel side walls (4) extending perpendicularly to the floor (3), a rear wall (13), and a ceiling part (5) disposed opposite the floor (3), which joins said side walls (4) and said rear wall (13), which device (1) further comprises a pipe (6) for discharging liquid from the reactor (2), which pipe (6) is disposed underneath the floor (3), and which device (1) further comprises means (7) for moisturising the material to be fermented that is present in the reactor (2) as well as means (8) for providing access to the reactor (2) for the purpose of supplying and discharging material (9) to be fermented and fermented material (9), respectively, and which device (1) furthermore comprises a pipe (14) for discharging biogas from the reactor (2).

摘要翻译： 一种装置（1）和在反应器（2）中进行发酵过程的方法，该反应器（2）包括透液性地板（3），垂直于地板延伸的两个基本平行的侧壁（4） 3），后壁（13）和与地板（3）相对设置的顶壁部分（5），其连接所述侧壁（4）和所述后壁（13），所述装置（1）还包括管 （6）用于从反应器（2）排出液体，该管道（6）设置在地板（3）的下方，并且该装置（1）还包括用于对待发酵材料进行保湿的装置（7） 反应器（2）以及用于提供进入反应器（2）的装置（8），用于分别供应和排放待发酵的材料（9）和发酵材料（9），以及哪个装置（1） 还包括用于从反应器（2）排出沼气的管道（14）。

公开(公告)号：EP1390480A1

公开(公告)日：2004-02-25

申请号：EP02738292.8

申请日：2002-05-31

申请人： TMI Europe

发明人： CASEZ, Hervé

IPC分类号： C12N9/08 ,  C12P3/00 ,  C12N11/00 ,  A61L2/16 ,  A01N59/24 ,  A01N63/00 ,  C12M1/40

CPC分类号： C12N9/0065 ,  A61L2/16 ,  C12M21/18 ,  C12M23/34 ,  C12M27/02 ,  C12M33/10 ,  C12M33/14 ,  C12M33/22 ,  C12M41/26 ,  C12N11/00 ,  C12P3/00

摘要： The invention relates to a method for the enzymatic production of a curing agent in its fluid state, e.g. liquid, comprising, in free phase, at least one oxygenated chemical species. Said method consists in bringing into contact at least: one enzymatic catalysis agent, comprising at least one peroxidase-type enzyme; an oxidisable substrate in aqueous phase that can be oxidised by the action of an oxygen donor, by catalysis by said enzymatic catalysis agent, generating said oxygenated chemical species in free phase; and said oxygen donor. The inventive method is characterised in that: e) an aqueous reaction bath is formed comprising, in addition to the oxidisable substrate and the oxygen donor, said enzymatic catalysis agent in divided solid phase, but in free phase, distributed in said bath, which may be set in motion; f) the aqueous reaction bath is separated into a fraction enriched with the enzymatic catalysis agent in divided solid phase and a fraction free from said catalysis agent, from which the curing agent is obtained.

公开(公告)号：EP1379673A2

公开(公告)日：2004-01-14

申请号：EP02721794.2

申请日：2002-04-22

申请人： E.I. DU PONT DE NEMOURS AND COMPANY

发明人： WILKINS, Antoinette, E. ,  LOWE, David, J.

IPC分类号： C12P1/00 ,  C12N9/00 ,  D06M16/00

CPC分类号： C12M47/12 ,  B01D15/1814 ,  B01D15/426 ,  C12M29/02 ,  C12M33/14 ,  C12M47/10 ,  C12N1/38 ,  C12P7/18

摘要： This invention relates to a bioprocess engineering solution for a product removal process for use in a biofermentation. The invention discloses a process for withdrawing an aliquot of broth from a biofermentation vessel during at least a portion of the biofermentation, removing biocatalyst and water, chromatographically separating biofermentation products from the withdrawn broth using water as an eluent, and returning the remaining components of the broth back to the biofermentation vessel. Process chromatography permits highly selective separation of the target molecule, preventing feedback inhibition of the biofermentation.

公开(公告)号：EP1089800B1

公开(公告)日：2003-11-12

申请号：EP99933568.0

申请日：1999-06-21

申请人： Thermo Biostar, Inc.

发明人： CROSBY, Mark, A.

IPC分类号： B01D35/00 ,  B01D29/05

CPC分类号： B01D29/05 ,  B01D29/78 ,  B01D29/822 ,  B01D35/00 ,  B01D2201/202 ,  C12M33/14 ,  Y10S435/975

摘要： The present invention involves a simple, disposable, manual filtration and extraction device and method of use that provides a sample directly to an analytical method. The device is capable of providing a clarified liquid ready for analysis or disposal as appropriate for the specific analyte of interest, and is capable of capturing particulate materials and allowing for further extraction of those particles directly with the device. Once extracted, the device will deliver a liquid containing the analyte of interest to an analytical method. The filtration and extraction devise includes a pliant body having an open top end and an internal wall defining an inner chamber. A sealing mechanism is adapted to seal the open top end of the body. A gradient filter assembly including at least one filter is supported by a support assembly carried by the body. The pliant body is adapted to be squeezed by a user's fingers so as to impart a positive pressure in the chamber sufficient to cause a fluid in the chamber to flow through the filter assembly.

公开(公告)号：EP1093572B1

公开(公告)日：2002-11-27

申请号：EP99935428.5

申请日：1999-07-07

申请人： LAMINA, INC.

发明人： EL-AMIN, Marianna ,  GUIRGUIS, Raouf, A. ,  SAMAAN, Nashed

IPC分类号： G01N1/38

CPC分类号： G01N1/4077 ,  B01F9/06 ,  B01F15/00506 ,  B01F15/0266 ,  B01F15/0291 ,  B01L3/502 ,  B01L3/508 ,  B01L2300/042 ,  B01L2300/046 ,  B01L2300/0681 ,  C12M33/04 ,  C12M33/14 ,  G01N1/2813 ,  G01N1/38

摘要： The invention is an apparatus and method for separating particulate matter from a fluid, wherein the apparatus includes a collection container, a porous arrangement positioned in a housing and suitable for collecting particulate matter in the liquid on a collection site, a pump, and a mixer having a rotating receptacle adapted to receive the specimen container. The apparatus includes a cover that has a portion that is fixed in a first position and freely rotatable in a second position.

公开(公告)号：EP1240307A1

公开(公告)日：2002-09-18

申请号：EP00979881.0

申请日：2000-12-18

申请人： MILLIPORE

发明人： LEMONNIER, Jean

IPC分类号： C12M1/12

CPC分类号： C12M41/40 ,  C12M29/04 ,  C12M33/14 ,  C12M41/36

摘要： This concerns a device for microbiological examination of a sample of liquid, having an intake body (2), a filtering membrane (4) and a drainage body (3) having means of supporting (48) said membrane on the opposite side from said intake body, these support means (48) having a concave surface facing said membrane (4). The drainage method proposes directly placing the device on a vacuum flask, the sealing of the stopper of said flask being obtained by a rib (40) tapering towards its end.

公开(公告)号：EP1169429A1

公开(公告)日：2002-01-09

申请号：EP00920736.6

申请日：2000-04-20

申请人： GEA Liquid Processing Scandanavia A/S

发明人： Pajunen, Esko Juhani ,  Lynch, Francis J. ,  Bergin, Joseph ,  Viljava, Timo Tapio ,  Andersen, Keld ,  Lommi, Heikki Olavi

IPC分类号： C12M1/40 ,  C12C11/09

CPC分类号： C12C11/07 ,  C12C11/075 ,  C12C11/09 ,  C12M23/24 ,  C12M23/58 ,  C12M25/02 ,  C12M25/20 ,  C12M29/18 ,  C12M29/20 ,  C12M33/10 ,  C12M33/14 ,  C12M41/18

摘要： The invention relates to a method for the continuous biocatalytic conversion of aqueous solutions containing biocatalytically convertible material in a reactor, having one or more converting/degassing stages in parallel or serial interconnection, each converting/degassing stage comprising a bioreactor and a degassing device in serial interconnection, where in each converting/degassing stage in a first process step an aqueous solution containing biocatalytically convertible material is fed in continuous flow to the inlet of the bioreactor where it is contacted with a biocatalyst, and where in a second process step the biocatalytically converted solution is transferred from an outlet of the bioreactor to an inlet of the degassing device, and at least part of the degassed solution leaving the outlet of the last degassing device in line is fed to the inlet of the first bioreactor in line in a continuous flow. The invention further relates to an apparatus for carrying out such a method.

公开(公告)号：EP1008646B1

公开(公告)日：2001-09-12

申请号：EP98811137.3

申请日：1998-11-13

申请人： van den Wildenberg, Pierre

发明人： van den Wildenberg, Pierre

IPC分类号： C12M1/26 ,  G01N1/24

CPC分类号： C12M23/10 ,  C12M23/38 ,  C12M33/04 ,  C12M33/14