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公开(公告)号：EP2609930A3
公开(公告)日：2013-07-17
申请号：EP13156164.9
申请日：2007-02-27
IPC分类号： A61K38/18
CPC分类号： A61K38/1883
摘要： Disclosed are methods of improving impaired proprioception, treating brachial plexus injuries, regenerating large and small nerve fibers, treating dorsal root nerve injuries, and improving sensory neural responses in a subject by administration of a neublastin polypeptide.
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公开(公告)号：EP1578884B1
公开(公告)日：2013-04-24
申请号：EP03716719.4
申请日：2003-03-19
IPC分类号： C09K9/00 , C08F220/34 , C08F220/50 , C08F222/30 , C08F290/06 , C08F290/14 , C08F293/00 , G02F1/361 , C08L53/00
CPC分类号： G02F1/3617 , C08F220/34 , C08F220/50 , C08F222/30 , C08F290/06 , C08F290/14 , C08F293/005 , C08L53/00 , C08L2666/02
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33.发明授权
公开(公告)号：EP2126625B1
公开(公告)日：2012-02-22
申请号：EP08705645.3
申请日：2008-01-02
IPC分类号： G02F1/35 , G11B7/24 , G11B7/0065 , G11C13/04 , G02F1/335
CPC分类号： G02F1/3501 , G02F1/397 , G03H2001/2655 , G03H2260/36 , G03H2260/54
摘要： A photorefractive device (100) and method of manufacture are disclosed. The device (100) comprises a layered structure in which one or more polymer layers (110) are interposed between a photorefractive material (106) and at least one transparent electrode layer (104). The layered structure is further interposed between a plurality of substrates (102). When a bias is applied to the device (100), the device (100) exhibits an increase in signal efficiency of approximately three to four times that of similar, but non-buffered, devices. Concurrently, the device (100) of the present disclosure utilizes approximately half the biased voltage, advantageously resulting in a longer device lifetime.
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34.发明公开CELLULAR SEEDING AND CO-CULTURE OF A THREE DIMENSIONAL FIBROBLAST CONSTRUCT 审中-公开细胞接种和三维共培养成纤维细胞CONSTRUCT
公开(公告)号：EP2417247A1
公开(公告)日：2012-02-15
申请号：EP10714515.3
申请日：2010-04-09
发明人： LANCASTER, Jordan , GOLDMAN, Steve
CPC分类号： C12N5/0657 , A61K35/33 , A61K35/34 , A61K45/06 , A61L27/3604 , A61L27/367 , A61L27/3826 , A61L2300/64 , A61L2430/20 , C12N5/0062 , C12N2502/1323 , C12N2502/28
摘要： The present invention provides methods for cellular seeding onto three-dimensional fibroblast constructs, three-dimensional fibroblast constructs seeded with muscle cells, and uses therefore.
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公开(公告)号：EP2396683A2
公开(公告)日：2011-12-21
申请号：EP10741835.2
申请日：2010-02-12
摘要： A diffractive multifocal lens is disclosed, comprising an optical element having at least one diffractive surface, the surface profile comprising a plurality of annular concentric zones. The optical thickness of the surface profile changes monotonically with radius within each zone, while a distinct step in optical thickness at the junction between adjacent zones defines a step height. The step heights for respective zones may differ from one zone to another periodically so as to tailor diffraction order efficiencies of the optical element. In one example of a trifocal lens, step heights alternate between two values, the even-numbered step heights being lower than the odd-numbered step heights. By plotting a topographical representation of the diffraction efficiencies resulting from such a surface profile, step heights may be optimized to direct a desired level oflight power into the diffraction orders corresponding to near, intermediate, and distance vision, thereby optimizing the performance of the multifocal lens.
摘要翻译： 公开了一种衍射多焦点透镜，其包括具有至少一个衍射表面的光学元件，所述表面轮廓包括多个环形同心区域。 表面轮廓的光学厚度在每个区域内以半径单调变化，而在相邻区域之间的连接处的光学厚度的不同步骤限定了台阶高度。 相应区域的台阶高度可以周期性地从一个区域到另一个区域不同，以便定制光学元件的衍射级效率。 在三焦透镜的一个示例中，步高在两个值之间交替，偶数步长高于奇数步长。 通过绘制由这种表面轮廓产生的衍射效率的形貌表示，可以优化步长以将期望的光强度引导到对应于近视，中间和远视的衍射级，从而优化多焦点透镜的性能 。
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公开(公告)号：EP2297349A1
公开(公告)日：2011-03-23
申请号：EP09759456.8
申请日：2009-06-04
申请人： The Arizona Board Of Regents On Behalf Of The University Of Arizona , Fred Hutchinson Cancer Research Center
IPC分类号： C12Q1/68 , G01N33/574
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/158 , G01N33/57426
摘要： The present invention provides methods and compositions for prognosing treatment outcome in DLBCL patients, diagnosing DLBCL and monitoring efficacy of DLBCL treatment.
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公开(公告)号：EP2219449A1
公开(公告)日：2010-08-25
申请号：EP08850106.9
申请日：2008-11-17
CPC分类号： A61K31/40
摘要： The invention features methods of treating visceral pain in humans by administering an effective amount of a 5HTIB or 5HTID receptor agonist, (e.g., a triptan). These methods can be used, for example, to treat a human suffering from visceral pain secondary to an underlying disease of a visceral organ, such as pancreatitis. Visceral pain treatable by the methods of the invention may also be secondary to a disease of the liver, kidney, ovary, uterus, bladder, bowel, stomach, esophagus, duodenum, intestine, colon, spleen, pancreas, appendix, heart, or peritoneum.
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38.发明公开SENSITIVE ION DETECTION DEVICE AND METHOD FOR ANALYSIS OF COMPOUNDS AS VAPORS IN GASES 审中-公开敏感离子检测设备和方法化合物作为气体蒸气的分析
公开(公告)号：EP2218092A2
公开(公告)日：2010-08-18
申请号：EP08871397.9
申请日：2008-11-06
IPC分类号： H01J49/12
CPC分类号： G01N27/622 , H01J49/02 , H01J49/10
摘要： An ion mobility spectrometer (IMS) for the detection of trace gaseous molecular compounds dissolved or suspended in a carrier gas, particularly in ambient air, without preconcentration or the trapping of analyte particles. The IMS of the invention comprises an ionization volume of greater than 5 cm
3 and preferably greater than 100 cm
3 . The larger size ionizers of this invention enable analysis of trace (-
公开(公告)号：EP2049447A2
公开(公告)日：2009-04-22
申请号：EP07761039.2
申请日：2007-04-20
发明人： STONE, David
CPC分类号： C09D1/06 , Y10T428/2993
摘要： An oxidatively carbonatable composition, a paste for forming an oxidatively carbonated composition, an oxidatively carbonated composition, methods of making an oxidatively carbonated composition, and articles formed from an oxidatively carbonated composition.
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公开(公告)号：EP2043434A2
公开(公告)日：2009-04-08
申请号：EP06848431.0
申请日：2006-12-01
CPC分类号： G01N33/56922 , G01N2333/205 , G01N2469/10 , G01N2469/20
摘要： The present disclosure provides coding and amino acid sequences for a Campylobacter jejuni pilus protein (and from other species as well). This protein, when administered to a human or animal, elicits the expression of an immune response to Campylobacter jejuni, with the result that colonization and/or infection by this organism is reduced. Recombinant protein or biofilm material comprising the pilus protein is formulated into immunogenic compositions, especially for mucosal administration. Thus, the present invention provides methods for improvement of the microbial quality of food products including poultry, eggs, meat and dairy products, and indirectly of plant foods that may come in contact with agricultural waste, either from fertilization or from irrigation water.
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