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72 条记录 (耗时 0.021 秒)

    Novel lipid compounds
    34.
    发明公开
    Novel lipid compounds 审中-公开
    Neue Lipidverbindungen

    公开(公告)号：EP2248798A1

    公开(公告)日：2010-11-10

    申请号：EP09159798.9

    申请日：2009-05-08

    申请人： Pronova BioPharma Norge AS

    发明人： Brændvang, Morten ,  Hovland, Ragnar ,  Holmeide, Anne, Kristin

    IPC分类号： C07C67/31 ,  C07C69/708 ,  C07C51/06 ,  C07C51/09 ,  C07C59/60 ,  A61P3/06 ,  A61K31/19 ,  A61K31/22

    CPC分类号： C07C69/708 ,  C07B2200/07 ,  C07C51/09 ,  C07C59/60 ,  C07C67/31 ,  C07C69/734

    摘要： The present invention relates to lipid compounds of the general formula (I):

    wherein R 1 is selected from a C 10 -C 22 alkyl, a C 10 -C 22 alkenyl having 1-6 double bonds, and a C 10 -C 22 alkynyl having 1-6 triple bonds;R 2 and R 3 are the same or different and may be selected from a group of different substituents; and X represents a carboxylic acid or a derivative thereof, such as a carboxylic ester, a carboxylic anhydride or a carboxamide;
    or a pharmaceutically acceptable salt, solvate, solvate of such salt or a prodrug thereof.
    The invention also relates to pharmaceutical compositions and lipid compositions comprising such compounds, and to such compounds for use as medicaments or for use in therapy, in particular for the treatment of diseases related to the cardiovascular, metabolic and inflammatory disease area.

    摘要翻译： 本发明涉及通式（I）的脂质化合物：其中R 1选自C 10 -C 22烷基，具有1-6个双键的C 10 -C 22烯基和C 10 -C 22 具有1-6个三键的炔基; R 2和R 3相同或不同，并且可以选自不同取代基的基团; X表示羧酸或其衍生物，例如羧酸酯，羧酸酐或羧酰胺; 或其药学上可接受的盐，溶剂化物，这种盐的溶剂合物或其前药。 本发明还涉及包含这些化合物的药物组合物和脂质组合物以及用作药物或用于治疗，特别是用于治疗与心血管，代谢和炎性疾病区域有关的疾病的化合物。

    LIPID COMPOUNDS FOR USE IN COSMETIC PRODUCTS, AS FOOD SUPPLEMENT OR AS A MEDICAMENT
    35.
    发明公开
    LIPID COMPOUNDS FOR USE IN COSMETIC PRODUCTS, AS FOOD SUPPLEMENT OR AS A MEDICAMENT 审中-公开
    脂类化合物，其用在化妆品中AS食物补充剂或作为药物

    公开(公告)号：EP2217224A1

    公开(公告)日：2010-08-18

    申请号：EP08846228.8

    申请日：2008-11-06

    申请人： Pronova BioPharma Norge AS

    发明人： HOLMEIDE, Anne Kristin

    IPC分类号： A61K31/10 ,  A23L1/29 ,  A61K31/22 ,  A61K8/46 ,  C07C321/14 ,  C07C321/18 ,  C07C323/03 ,  C07C323/05

    CPC分类号： A61K31/00 ,  A23L33/115 ,  A61K8/46 ,  A61K2800/92 ,  A61Q19/06 ,  C07C323/12

    摘要： The present invention relates to lipid compounds of the general formula (I): wherein • R1 is selected from a C10-C21 alkyl, a C10-C21 alkenyl having 1-6 double bonds, and a C10-C21 alkynyl having 1-6 triple bonds; • R2 and R3 are the same or different and are selected from hydrogen and a C1-C6 alkyl group; and X is selected from O, S, SO, SO2, Si or Se; • n = 1 or 3; and • P1 is selected from a hydrogen, a C10-C21 alkyl, a C10-C21 alkenyl having 1-6 double bonds, and a C10-C21 alkynyl having 1-6 triple bonds, optionally substituted; or P1 is represented by: wherein P2, P3 and P4 are selected from a hydrogen, an alkyl, alkenyl, alkynyl, optionally substituted; or P1 is a phosphonate or a phosphate ester, represented by or P1 is a sulphonate or a sulphate ester, represented by wherein P5 is a hydrogen or a C1-C6 alkyl; or a pharmaceutically acceptable salt, complex or solvate thereof. Also disclosed are pharmaceutical compositions and lipid compositions comprising such compounds, and such compounds for use as medicaments, in particular for the treatment of diseases related to the cardiovascular, metabolic and inflammatory disease area.

    A process for decreasing environmental pollutants in an oil or a fat, and a fish feed product
    37.
    发明公开
    A process for decreasing environmental pollutants in an oil or a fat, and a fish feed product 审中-公开
    一种用于环境污染物的油减少或脂肪和鱼饲料产品的方法

    公开(公告)号：EP2169038A1

    公开(公告)日：2010-03-31

    申请号：EP09180207.4

    申请日：2003-07-08

    申请人： Pronova BioPharma Norge AS

    发明人： Breivik, Harald ,  Thorstad, Olav

    IPC分类号： C11B3/12 ,  A23D9/00

    CPC分类号： C11B3/006 ,  A23D9/00 ,  A23K20/158 ,  A23K50/80 ,  A23L33/115 ,  A23V2002/00 ,  C11B3/12 ,  C11B3/14 ,  C11C3/10 ,  Y02A40/818 ,  A23V2200/3262

    摘要： The invention relates to a process for decreasing the amount of environmental pollutants in a mixture comprising a fat or an oil, being edible or for use in cosmetics, the fat or oil containing the environmental pollutants, which process comprises the steps of adding a volatile working fluid to the mixture, where the volatile working fluid comprises at least one of a fatty acid ester, a fatty acid amide, a free fatty acid and a hydrocarbon, and subjecting the mixture with the added volatile working fluid to at least one stripping processing step, in which an amount of environmental pollutant present in the fat or oil, being edible or for use in cosmetics, is separated from the mixture together with the volatile working fluid. The present invention also relates to a volatile environmental pollutants decreasing working fluid, for use in decreasing an amount of environmental pollutants present in a fat or oil, being edible or for use in cosmetics. In addition, the present invention relates to a health supplement, a pharmaceutical and an animal feed product prepared according to the process mentioned above.

    摘要翻译： 易失性本发明涉及一种方法，用于降低混合物的环境污染物的量的包含脂肪或油中，作为可食用或用于化妆品中，所述脂肪或油包含的环境污染物，该方法包括添加一个工作的步骤 流体混合物中，其中挥发性工作流体包含脂肪酸酯中的至少一种，脂肪酸酰胺，游离脂肪酸和烃，和与所添加的挥发性工作流体使该混合物的至少一个汽提处理步骤 在其中在所述脂肪或油的量环境污染物的存在，作为食用或用于化妆品中，从该混合物中一起与挥发性工作流体分开。 因此，本发明涉及易失性环境污染物降低工作流体，其用于在存在于脂肪或油，是可食用或用于化妆品中的环境污染物的量的减少。 此外，本发明涉及一种保健品，药物和动物饲料产物制备雅丁上面提到的过程。