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31.发明公开ANTI-TUBERCULOSIS STABLE PHARMACEUTICAL COMPOSITION IN A FORM OF A DISPERSIBLE TABLET COMPRISING GRANULES OF ISONIAZID AND GRANULES OF RIFAPENTINE AND ITS PROCESS OF PREPARATION 审中-公开结核病耐受药物组合物中，可分散的平板电脑与GRANULAT OFF异烟肼和一个GRANULAT OFF利福喷丁及其制造方法的形式
公开(公告)号：EP3024444A1
公开(公告)日：2016-06-01
申请号：EP14741647.3
申请日：2014-07-22
申请人： SANOFI
IPC分类号： A61K9/20 , A61K9/24 , A61K31/4409 , A61K31/496
CPC分类号： A61K9/209 , A61K9/0053 , A61K9/2077 , A61K9/2086 , A61K9/2095 , A61K31/4409 , A61K31/496 , A61K2300/00
摘要： The present invention relates to an oral pharmaceutical fixed dose composition in a form of a dispersible tablet for use in the treatment of tuberculosis, said oral pharmaceutical composition comprising: a) granules comprising isoniazid and at least one intragranular excipient, b) granules comprising rifapentine and at least one intragranular excipient, and c) at least one extragranular excipient, and to its process of preparation.
摘要翻译： 本发明在用于在治疗结核病中使用的可分散片剂的形式口服药物的固定剂量组合物，涉及，所述口腔药物组合物，包括：a）颗粒，其包括异烟肼和至少一种颗粒内赋形剂，B）颗粒，其包括利福喷汀和 至少一种颗粒内赋形剂，和c）至少一种颗粒外赋形剂，和其制备的过程。
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32.发明公开ANTI-TUBERCULOSIS STABLE PHARMACEUTICAL COMPOSITION IN A FORM OF A COATED TABLET COMPRISING GRANULES OF ISONIAZID AND GRANULES OF RIFAPENTINE AND ITS PROCESS OF PREPARATION 审中-公开稳定药用组合物，预防结核病与来自异烟肼和利福喷丁GRANULAT OFF颗粒和其制造方法的薄膜片剂的形式
公开(公告)号：EP3024443A1
公开(公告)日：2016-06-01
申请号：EP14741646.5
申请日：2014-07-22
申请人： SANOFI
IPC分类号： A61K9/20 , A61K9/24 , A61K31/4409 , A61K31/496
CPC分类号： A61K9/209 , A61K9/2022 , A61K9/2077 , A61K31/4409 , A61K31/496 , A61K31/70 , A61K2300/00
摘要： The present invention relates to an oral pharmaceutical fixed dose composition for use in the treatment of tuberculosis, said oral pharmaceutical composition comprising: a) granules comprising isoniazid and at least one intragranular excipient, b) granules comprising rifapentine and at least one intragranular excipient, and c) at least one extragranular excipient, and to its process of preparation.
摘要翻译： 本发明在用于治疗结核病的用途口服药物的固定剂量组合物，涉及，所述口腔药物组合物，包括：a）颗粒，其包括异烟肼和至少一种颗粒内赋形剂，B）颗粒，其包括利福喷汀和至少一种颗粒内赋形剂，和 c）至少一个颗粒外赋形剂，和其制备的过程。
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公开(公告)号：EP2807172A1
公开(公告)日：2014-12-03
申请号：EP13712331.1
申请日：2013-01-25
申请人： SANOFI
发明人： BRAUN, Alain , CRESPIN, Olivier , FORICHER, Yann , MARCINIAK, Gilbert , MUZET, Nicolas , NICOLAI, Eric , PASCAL, Cécile , VIVET, Bertrand , VIVIANI, Fabrice
IPC分类号： C07D498/04 , A61K31/519
CPC分类号： C07D498/04 , C07D519/00
摘要： The invention relates to bicydic heterocyclic derivatives of general formula (I) to a process for preparing them and to the therapeutic use thereof.
摘要翻译： 本发明涉及通式（I）的双二元杂环衍生物及其制备方法及其治疗用途。
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34.发明公开FGF RECEPTOR (FGFR) AGONIST DIMERIC COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND THERAPEUTIC USE THEREOF 有权FGF受体（FGFR）激动剂二聚体化合物，其制备方法及其治疗用途
公开(公告)号：EP2797930A1
公开(公告)日：2014-11-05
申请号：EP12824733.5
申请日：2012-12-26
申请人： SANOFI
IPC分类号： C07D519/00 , A61K31/517 , A61P9/10
CPC分类号： C07D471/04 , C07D519/00
摘要： The invention relates to novel heterocyclic compounds which are pyrazolopyridine derivatives that induce FGFR dimerization, having the general formula: M -L-M 2 in which M and M 2, which may be identical or different, each represent, independently of one another, a monomer unit Mand L represents a linker group which links M
1 and M
2 covalently with the monomer unit which follows (Formula M). Process for the preparation thereof and therapeutic use thereof.-
35.发明公开DERIVES DE 5 - OXO -5, 8- DIHYDROPYRIDO [2, 3 - D]PYRIMIDINE COMME INHIBITEURS DE KINASES CAMKII POUR LE TRAITEMENT DE MALADIES CARDIOVASCULAIRES 有权5-氧代-5,8-二氢吡啶并[2,3-D]嘧啶衍生物AS CAMKII-激酶的抑制剂对心血管疾病治疗
公开(公告)号：EP2521726A1
公开(公告)日：2012-11-14
申请号：EP11704258.0
申请日：2011-01-06
申请人： SANOFI
IPC分类号： C07D471/04 , A61K31/519 , A61P9/00
CPC分类号： C07D471/04
摘要： The invention relates to 5-oxo-5, 8-dihydropyrido [2, 3-d] pyrimidine derivatives of the general Formula (I). The invention also relates to the method for preparing same and to therapeutic use thereof.
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36.发明公开OLIGOSACCHARIDES N-SULFATES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PRÉPARATION ET LEUR APPLICATION EN THÉRAPEUTIQUE 审中-公开N-硫酸寡糖的FGFs受体活化它们的合成及治疗应用
公开(公告)号：EP2464359A2
公开(公告)日：2012-06-20
申请号：EP10761048.7
申请日：2010-08-12
申请人： SANOFI
IPC分类号： A61K31/737 , C08B37/00 , A61P7/00 , A61P9/00 , A61P11/00 , A61P17/00 , A61P19/00 , A61P21/00 , A61P25/00 , A61P27/02 , A61P37/00
CPC分类号： C08B37/0063 , A61K31/737 , C07H11/00 , C07H15/04 , C07H15/203 , C08B37/0075
摘要： The invention relates to FGF receptor-activating N-sulfate oligosaccharides having Formula (I), wherein R
1 , R
4 , R
6 , and R
8 are OSO
3 - or hydroxyl groups, R
2 is an O-alkyl group or a monosaccharide having Formula (II), R
3 is a disaccharide having Formula (III), R
5 is a disaccharide having Formula (IV), R
7 is a hydroxyl group or a disaccharide having Formula (VI), and R
9 is a hydroxyl or O-alkyl group or a disaccharide having Formula (VII), where R
10 is an O-alkyl group. The invention further relates to the preparation of said oligosaccharides and to the therapeutic use thereof.
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