摘要:
A ventilatory valve (40) that is devised to control a pressure level in a patient breathing circuit of an anesthetic breathing apparatus is disclosed. The ventilatory valve comprises a valve unit having a controllable restriction to control the pressure level in an expiratory branch of the breathing circuit of the anesthetic breathing apparatus, an electrical operating unit for the valve unit, configured to electrically control the restriction during electrical operation of the anesthetic breathing apparatus, and a non-electrical operating unit (100) for the valve unit, configured to non-electrically control the restriction upon electrical defective or powerless operation of the anesthetic breathing apparatus.
摘要:
A tissue cutting device is disclosed, comprising a tubular part, that is structured and arranged to be inserted in a temporary delivery shape through a vascular system into a body vessel, and to be subsequently subjected to a change of shape, from said temporary delivery shape via an expanded delivered shape to a further expanded shape, extending at least beyond an outer surface of said body vessel in order to create a cutting action configured for cutting said body vessel, wherein said tissue cutting device is structured and arranged to penetrate a wall of said body vessel by said cutting action, in such a manner that a cut of said tissue created by said cutting action is continuously replaced by scar tissue, wherein the tubular part of said device comprises a plurality of segments connected to each other in longitudinal direction of said tubular part of said device, wherein a first segment of said plurality of segments has a dimension in a direction perpendicular to said longitudinal direction of said tubular part of said device that is larger than that dimension of a second segment thereof, at least in said expanded delivered shape.
摘要:
A topical dermal delivery device, such as a patch, for topical delivery of nitric oxide (NO) to treatment sites of mammals is disclosed. In an embodiment the patch has three layers; a backing with an activation window, a absorbent core as a reservoir and an NO permeable membrane with an adhesive layer towards the skin. The NO donor is applied into the device as a solution prior to application through the activation window. The window is closed after activation and the lid and backing is non-permeable for NO in order to increase the partial pressure of NO and thus the concentration of dissolved NO. The patch is fixated on the area to be treated with an adhesive layer that also assures sufficient contact throughout the treatment. The generated NO moves within the patch and can escape through the NO permeable membrane towards the area to be treated. Depending on therapy needed, the patch release curve differs and is chosen accordingly.
摘要:
An application for a device for human conveyance includes a front wheel and a rear wheel. The rear wheel interfaced to a sprocket through a ratchet drive system which allows forward rotation of the rear wheel in response to forward rotation of the sprocket and allows free backward rotation of the sprocket. A frame interfaces the front wheel to the rear wheel keeping the front wheel at a constant distance from the rear wheel. The front and rear wheels are rotatably interfaced to the frame. A front end of an arc-shaped spring is affixed to the frame in proximity to the front wheel and a rear end of the arc-shaped spring has a sprocket gear interfaced to the sprocket whereas depression of the arc-shaped spring pushes the rear-end of the arc-shaped spring in a rearward direction with respect to the rear wheel and the sprocket gear turns the sprocket in a forward rotational direction.
摘要:
The present invention relates to biocompatible microemulsion systems designed for controlled release drug delivery applications formulated with phospholipids such as lecithin (surfactant), a lipophilic additive (linker) containing 9 or more carbons in their alkyl group and hydrophilic-lipophilic balance (HLB) of 5 or less, and a surfactant-like hydrophilic additive (linker) containing between 6 to 9 carbon atoms in their alkyl tail. The combination of linkers and phospholipids produce formulations capable of delivering high concentrations of poorly soluble drugs into epithelial tissue using low surfactant concentrations, with minimum cytotoxic side effects.
摘要:
An artificial joint including a main body and a lower portion adapted to pivotally engage the main body about a control axis while having a locking means that is integral with the lower portion. An upper portion adapted to pivotally engage the main body about a flexing axis and has an engagement means adapted to engage and disengage the locking means upon the pivoting rotation of the upper portion relative the main body. A biasing means is adapted to engage both the main body and the lower portion thereby biasing the locking means to engage the engagement means, and at least one stopping surface adapted to limit motion between the main body and the lower portion. The locking means is activated when a load is imposed on the artificial joint and passes through a line posterior to the control axis, and is desactivated when the load passes through a line anterior to the control axis.
摘要:
Described are equipment, a system, a kit and a method for the performance of a minimally-intensive body access, such as cardiac access. Epicardial Access Surgery (EAS) is disclosed. EAS does not need general anesthesia or extracorporeal circulation nor does it need a chest opening, which is very advantageous for various aspects. For instance an operation of a coronary artery bypass is created by creating a direct path of flow from one body artery into a coronary artery with the aid of catheter-based minimally-invasive EAS based bypass surgery. In addition, various medical devices are used, such as a special partially flexible needle, a special partially covered stent, and a special partially flexible port.
摘要:
The present invention generally relates to the use of small particles, such as micro particles or nanoparticles, to produce a therapeutic scar such as 'trans-mural' scarring or other desired 'deep tissue' scarring. In one preferred embodiment, these particles can be delivered to a target location by an implant. More specifically, these particles can be incorporated into the structure of implants or into the coatings on implants. In another preferred embodiment, these small particles can be delivered directly with a catheter by electrophoresis or hydraulic pressure.
摘要:
A system and method for interactive interstitial photo-dynamic tumour therapy and/or photothermal tumour therapy of a human or animal, said system comprising at least one radiation distributor, which is arranged for distribution of optical radiation from at least one radiation source to a reaction site, or from the reaction site to at least one radiation sensor. The radiation distributor comprises at least one translatory displacement element being translatory movable relatively to another element. First ends of first radiation conductors are fixed to the first translatory displacement element and first ends of second radiation conductors are fixed to the other element, wherein the first and the second radiation conductors are connectable to each other in different constellations through translatory movement of the translatory displacement element and the other element relative each other in order to obtain different operation modes of said system.
摘要:
The present invention provides a rotary blood pump with both an attractive magnetic axial bearing and a hydrodynamic bearing. In one embodiment according to the present invention, a rotary pump includes an impeller assembly supported within a pump housing assembly by a magnetic axial bearing and a hydrodynamic bearing. The magnetic axial bearing includes at least two magnets oriented to attract each other. One magnet is positioned in the spindle of the pump housing while the other is disposed within the rotor assembly, proximate to the spindle. In this respect, the two magnets create an attractive axial force that at least partially maintains the relative axial position of the rotor assembly. The hydrodynamic bearing is formed between sloping surfaces that form tight clearances below the rotor assembly.