利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

52 条记录 (耗时 0.026 秒)

    A METHOD AND A SYSTEM FOR COUNTING CELLS FROM A PLURALITY OF SPECIES
    31.
    发明公开
    A METHOD AND A SYSTEM FOR COUNTING CELLS FROM A PLURALITY OF SPECIES 审中-公开
    方法和系统，用于计算几种物种的细胞

    公开(公告)号：EP1404875A1

    公开(公告)日：2004-04-07

    申请号：EP02747248.9

    申请日：2002-06-10

    申请人： ChemoMetec A/S

    发明人： SKYGGEBJERG, Ole ,  GLENSBJERG, Martin

    IPC分类号： C12Q1/68 ,  G01N15/14

    CPC分类号： G01N15/147 ,  G01N2015/1006 ,  G01N2015/1477

    摘要： The present invention relates to a method and a system for the assessment cells in a liquid sample. The present method provides individual counts of substantially all the cells in the sample which are susceptible to the method of making cells distinguishable, in a manner whereby it is not necessary to conduct calibrations between assessments of samples with cells from different species within one taxonomic group. This is provided by measuring a part of the cells having substantially identical spatially confined identifiable substances, such as DNA. This makes the method less sensitive to variations in cell size and morphology than prior art methods for cell counting, such as Coulter counting.

    METHOD AND APPARATUS FOR DETECTING FLUORESCENCE OF A SAMPLE
    33.
    发明公开
    METHOD AND APPARATUS FOR DETECTING FLUORESCENCE OF A SAMPLE 有权
    VERFAHREN UND VORRICHTUNG ZUR ERKENNUNG DER FLUORESZENZ EINER PROBE

    公开(公告)号：EP1290427A1

    公开(公告)日：2003-03-12

    申请号：EP01923535.7

    申请日：2001-04-11

    申请人： ChemoMetec A/S

    发明人： HANSEN,Frans Ejner Ravn

    IPC分类号： G01N21/64

    CPC分类号： G01N21/645 ,  G01N15/1468 ,  G02B21/0076 ,  G02B21/16 ,  G02B21/361

    摘要： The present invention relates to an apparatus and a method for detecting the fluorescence of a sample, wherein the apparatus comprises excitation light source located on the same side of the sample as the detecting means. The apparatus may be constructed as a single-sided as well as a double-sided system, wherein the double-sided system comprises double-sided excitation system and/or double-sided detecting system. The double-sided system may also be a combination of fluorescence system and conventional microscopy. The apparatus may be used for analysis of various types of biological material, liquid as well as solid material, and various other types of material suitable being analysed through fluorescence studies.

    摘要翻译： 本发明涉及一种用于检测样品荧光的装置和方法，其中该装置包括位于与检测装置相同侧的样品的激发光源。 该装置可以构造为单面和双面系统，其中双面系统包括双面激励系统和/或双面检测系统。 双面系统也可以是荧光系统和常规显微镜的组合。 该装置可用于分析各种类型的生物材料，液体和固体材料，以及适用于通过荧光研究分析的各种其他类型的材料。

    IMAGE FORMING CYTOMETER
    37.
    发明公开
    IMAGE FORMING CYTOMETER 审中-公开
    图像形成细胞仪

    公开(公告)号：EP3004838A1

    公开(公告)日：2016-04-13

    申请号：EP14733071.6

    申请日：2014-05-28

    申请人： ChemoMetec A/S

    发明人： GLENSBJERG, Martin ,  HOLM, Johan ,  KJÆRULFF, Søren ,  RAVN HANSEN, Frans Ejner

    IPC分类号： G01N15/14

    CPC分类号： G01N15/1434 ,  G01N2015/0065 ,  G01N2015/1006 ,  G01N2015/1438 ,  G01N2015/144 ,  G06K9/00127 ,  G06T7/0012 ,  G06T2207/10056 ,  G06T2207/10064 ,  G06T2207/30024

    摘要： The present invention relates to methods and systems for image cytometry analysis, typically at low optical magnification, where analysis is based on detection of biological particles using UV bright field, dark field or one or more sources of excitation light. The system comprises illumination means (11, 112), a sample holder (100), a sample compartment (101), imaging means (120), collection means (121), light modulation means (122, 123), and detection means (130) with active detection elements (131).

    摘要翻译： 本发明涉及典型地在低光学放大率下进行图像细胞术分析的方法和系统，其中分析基于使用UV明场，暗场或一个或多个激发光源的生物粒子的检测。 该系统包括照明装置（11,112），样品架（100），样品室（101），成像装置（120），收集装置（121），光调制装置（122,123）和检测装置（ 130）与有源检测元件（131）。

    METHOD FOR ANALYSIS OF CELLULAR DNA CONTENT
    38.
    发明公开
    METHOD FOR ANALYSIS OF CELLULAR DNA CONTENT 审中-公开
    VERFAHREN ZUR ANALYZE VONZELLULÄREMDNA-GEHALT

    公开(公告)号：EP2534463A1

    公开(公告)日：2012-12-19

    申请号：EP11705805.7

    申请日：2011-02-10

    申请人： ChemoMetec A/S

    发明人： KJÆRULFF, Søren ,  GLENSBJERG, Martin

    IPC分类号： G01N1/30 ,  C12Q1/68 ,  G01N15/14

    摘要： Disclosed is a fast and simple method for quantification of nucleic acid of biological cells as 2-step protocol. In the first step cells are treated with an acidic solution containing a non-ionic detergent and a fluorescent DNA specific label. In the second step the sample may be neutralized. Determining of the content of nucleic can be performed by fluorescence microscopy. The method may also be used for obtaining information of cell cycle analysis, ploidy determination, measurements of nucleotide incorporation and assays for proliferation, health, stress level, apoptosis, necrosis, or other state of conditions of cells. The invention also relates to a kit of parts comprising an acidic agent, a detergent, a labelling agent and optionally a neutralization agent.

    摘要翻译： 公开了一种用于定量生物细胞核酸的快速和简单的方法，作为2步方案。 在第一步中，用含有非离子洗涤剂和荧光DNA特异性标记的酸性溶液处理细胞。 在第二步中，样品可能被中和。 核酸含量的测定可以通过荧光显微镜进行。 该方法还可用于获得细胞周期分析，倍性测定，核苷酸掺入测定和增殖测定，健康，应激水平，凋亡，坏死或其他细胞状态的信息。 本发明还涉及包含酸性试剂，洗涤剂，标记试剂和任选的中和剂的试剂盒。