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52 条记录 (耗时 0.024 秒)

    METHOD AND KIT FOR ASSESSING VIABLE CELLS
    4.
    发明公开
    METHOD AND KIT FOR ASSESSING VIABLE CELLS 审中-公开
    方法和试剂盒FOR法官活菌

    公开(公告)号：EP2312943A2

    公开(公告)日：2011-04-27

    申请号：EP09776240.5

    申请日：2009-07-13

    申请人： Chemometec A/S

    发明人： SKINDERSØ, Mette Elena ,  SØRENSEN, Helle Frobøse ,  KJÆRULFF, Søren

    IPC分类号： A01N1/02 ,  G01N15/14 ,  G01N21/64 ,  G01N33/50

    CPC分类号： G01N33/582 ,  C09B15/00 ,  C09B57/00 ,  C09B57/02 ,  G01N21/6428 ,  G01N33/502 ,  G01N33/583 ,  G01N2021/6439 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2510/00

    摘要： The present invention provides simple, rapid methods and procedures for analyzing cells, hereunder quantitative and qualitative assessment of cells, such as viability. The present invention relates to the use of various optionally substituted reporter compounds particularly detectable upon their reaction with thiol-containing species present in higher concentrations in intact (e.g., living) cells than in non-intact (e.g., dead, stressed and apoptotic) cells. The present invention also relates to the use of various optionally substituted reporter compounds particularly detectable upon their reaction with species present in intact and/or non-intact cells. Moreover, the present invention relates to the use of measuring techniques and/or instruments coupled with the use of various optionally substituted reporter compounds. The invention further relates to compositions used in methods for analyzing cells, such as a composition comprising N-(7-dimethylamino-4-methyl-3-coumarinyl)-maleimide (DACM).

    A method and a system for determination of particles in a liquid sample
    5.
    发明公开
    A method and a system for determination of particles in a liquid sample 失效
    测定液体样品中颗粒的方法和系统

    公开(公告)号：EP1947443A3

    公开(公告)日：2008-07-30

    申请号：EP08101764.2

    申请日：1998-05-05

    申请人： ChemoMetec A/S

    发明人： Hansen, Frans Ejner Ravn ,  Glensbjerg, Martin ,  Arnvidarson, Börkur ,  Jeppesen, Jesper Myron

    IPC分类号： G01N15/14 ,  G01N33/04

    CPC分类号： G01N15/1459 ,  B01L3/5027 ,  G01N15/1463 ,  G01N21/31 ,  G01N21/59 ,  G01N21/6428 ,  G01N21/6458 ,  G01N21/76 ,  G01N33/04 ,  G01N2015/025 ,  G01N2015/1452 ,  G01N2015/1486 ,  G01N2021/5957 ,  G01N2021/6491

    摘要： The present invention relates to a method for the assessment of quantity and quality parameters of biological particles in a liquid analyte material. The method comprises applying a volume of a liquid sample to an exposing domain from which exposing domain electromagnetic signals from the sample in the domain can pass to the exterior, and exposing, onto an array of active detection elements such as CCD-elements, a spatial representation of electromagnetic signals having passed from the domain, the representation being detectable as an intensity by individual active detection elements, under conditions permitting processing of the intensities detected by the array of detection elements during the exposure in such a manner that representation of electromagnetic signals from the biological particles are identified as distinct from representations of electromagnetic signals from background signals. The exposing domain has an average interior thickness of between 20 μm and 200 μm.

    摘要翻译： 本发明涉及用于评估液体分析物材料中生物颗粒的数量和质量参数的方法。 该方法包括将一定体积的液体样品施加到曝光区域，从该区域中的样品暴露域电磁信号可以将该液体样品传递到外部，并且将活性检测元件阵列（例如CCD元件）暴露在曝光区域的空间 在允许在曝光期间处理由检测元件阵列检测到的强度的条件下，从该域通过的电磁信号的表示可以作为单个有源检测元件的强度来检测， 生物粒子被识别为不同于来自背景信号的电磁信号的表示。 曝光区域的平均内部厚度在20μm和200μm之间。

    A method for determination of biological particles in a liquid analyte material
    6.
    发明公开
    A method for determination of biological particles in a liquid analyte material 失效
    Verfahren zur Bestimmung von biologischen Teilchen in einemflüssigenAnalysematerial

    公开(公告)号：EP1933127A1

    公开(公告)日：2008-06-18

    申请号：EP08101751.9

    申请日：1998-05-05

    申请人： ChemoMetec A/S

    发明人： Hansen, Frans Ejner Ravn ,  Glensbjerg, Martin ,  Arnvidarson, Börkur ,  Jeppesen, Jesper Myron

    IPC分类号： G01N15/02 ,  G01N15/14

    CPC分类号： G01N15/1459 ,  B01L3/5027 ,  G01N15/1463 ,  G01N21/31 ,  G01N21/59 ,  G01N21/6428 ,  G01N21/6458 ,  G01N21/76 ,  G01N33/04 ,  G01N2015/025 ,  G01N2015/1452 ,  G01N2015/1486 ,  G01N2021/5957 ,  G01N2021/6491

    摘要： The present invention relates to a method for the assessment of quantity and quality parameters of biological particles in a liquid analyte material. The method comprises applying a volume of a liquid sample to an exposing domain from which exposing domain electromagnetic signals from the sample in the domain can pass to the exterior, and exposing, onto an array of active detection elements such as CCD-elements, a spatial representation of electromagnetic signals having passed from the domain, the representation being detectable as an intensity by individual active detection elements, under conditions permitting processing of the intensities detected by the array of detection elements during the exposure in such a manner that representation of electromagnetic signals from the biological particles are identified as distinct from representations of electromagnetic signals from background signals. The size of the volume of the liquid sample is sufficiently large to permit the assessment of the quantity and quality parameters to fullfil a predetermined requirement to the statistical quality of the assessment based on substantially one exposure.

    摘要翻译： 本发明涉及一种用于评估液体分析物质中生物颗粒的数量和质量参数的方法。 该方法包括将一定体积的液体样本施加到曝光区域，从该区域中的来自样品的区域电磁信号可以从该域暴露于外部，并将其暴露于诸如CCD元件的主动检测元件的阵列上， 在从曝光期间通过检测元件阵列检测到的强度处理的条件下，可以通过单独的有源检测元件作为强度检测该表示作为强度的表示， 生物颗粒被识别为不同于来自背景信号的电磁信号的表示。 液体样品的体积大小足够大以允许评估数量和质量参数，以基于基本上一次暴露来满足对评估的统计质量的预定要求。

    INTERFEROMETER ACTUATOR
    8.
    发明公开
    INTERFEROMETER ACTUATOR 审中-公开
    干涉传动器

    公开(公告)号：EP2156138A1

    公开(公告)日：2010-02-24

    申请号：EP08734546.8

    申请日：2008-04-21

    申请人： ChemoMetec A/S

    发明人： ARNVIDARSON, Börkur

    IPC分类号： G01B9/02

    CPC分类号： G01B9/02076 ,  G01B9/02068 ,  G01J3/02 ,  G01J3/0202 ,  G01J3/0256 ,  G01J3/06 ,  G01J3/453 ,  H01L41/0946 ,  H01L41/0973

    摘要： The invention relates the movement of at least one movable means of an interferometer relative to the body of the interferometer. The system according to the invention, comprises at least two interferometer actuators, that can be operated individually, so that the at least two actuators are capable of moving the at least one movable means of the interferometer. When activating at least one of the at least two interferometer actuators the at least one movable means of the interferometer is moved with a minimum need for correcting for e.g. tilt. In a preferred configuration the system and the method according to the invention comprises three interferometer actuators that can be operated individually.