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公开(公告)号:EP3947742A1
公开(公告)日:2022-02-09
申请号:EP20784828.4
申请日:2020-04-01
申请人: Grail, LLC
发明人: LO, Yuk-Ming Dennis , CHIU, Rossa Wai Kwun , CHAN, Kwan Chee , JIANG, Peiyong , LAM, Wai Kei , JI, Lu
IPC分类号: C12Q1/6886 , C12Q1/6883 , G01N33/48
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公开(公告)号:EP3938534A1
公开(公告)日:2022-01-19
申请号:EP20769284.9
申请日:2020-03-12
申请人: Grail, LLC
发明人: FILIPPOVA, Darya , LARSON, Matthew, H. , MAHER, M., Cyrus , PORTELA DOS SANTOS PIMENTEL, Monica , CALEF, Robert Abe Paine
IPC分类号: C12Q1/6806 , C12Q1/6869 , C12Q1/6886 , C04B40/06
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公开(公告)号:EP4413151A1
公开(公告)日:2024-08-14
申请号:EP22877903.9
申请日:2022-09-29
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6883 , C12Q1/701 , C12Q2600/11820130101
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34.
公开(公告)号:EP4357455A3
公开(公告)日:2024-07-24
申请号:EP24161229.0
申请日:2017-12-12
申请人: Grail, LLC
发明人: LARSON, Matthew
IPC分类号: C12Q1/6844 , C12Q1/6853 , C12Q1/6855 , C12N15/10
CPC分类号: C12Q1/6844 , C12Q1/6853 , C12Q1/6855 , C12N15/1096 , C12Y605/01003 , C12Y207/07049
摘要: Aspects of the invention include methods for preparing sequencing libraries comprising a plurality of RNA molecules. In some embodiments, the subject methods comprise sequencing at least a portion of a sequencing library to obtain sequencing data or sequence reads from a test sample (e.g., a biological sample from a subject).
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公开(公告)号:EP4353834A3
公开(公告)日:2024-05-01
申请号:EP23217634.7
申请日:2020-01-24
申请人: Grail, LLC
发明人: VENN, Oliver Claude , FIELDS, Alexander P. , GROSS, Samuel S. , LIU, Qinwen , SCHELLENBERGER, Jan , BREDNO, Joerg , BEAUSANG, John F. , SHOJAEE, Seyedmehdi , SAKARYA, Onur , MAHER, M. Cyrus , JAMSHIDI, Arash
IPC分类号: C12Q1/6886 , C12Q1/6832
CPC分类号: C12Q1/6886 , C12Q2600/15420130101 , C12Q1/6832
摘要: The present invention provides a method of assaying a sample for presence of nucleic acids from cells of a cancer type in a subject, the method comprising capturing converted cell-free DNA (cfDNA) fragments from the sample or amplification products thereof with a composition comprising a plurality of different bait oligonucleotides.
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公开(公告)号:EP4320269A1
公开(公告)日:2024-02-14
申请号:EP22784117.8
申请日:2022-04-08
发明人: LO, Yuk-Ming Dennis , CHIU, Rossa Wai Kwun , CHAN, Kwan Chee , JIANG, Peiyong , CHAN, Wing Yan , NI, Meng , HAN, Diana Siao Cheng , SIN, Tsz Kwan
IPC分类号: C12Q1/6827 , C12Q1/6886 , C12Q1/6883 , C12Q1/6869
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公开(公告)号:EP4168571A1
公开(公告)日:2023-04-26
申请号:EP21740402.9
申请日:2021-06-20
申请人: Grail, LLC
IPC分类号: C12Q1/6806 , C12Q1/6827
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公开(公告)号:EP4165206A2
公开(公告)日:2023-04-19
申请号:EP21826943.9
申请日:2021-06-16
申请人: Grail, LLC
IPC分类号: C12Q1/6809 , C12Q1/6886
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公开(公告)号:EP4127231A1
公开(公告)日:2023-02-08
申请号:EP21720117.7
申请日:2021-03-29
申请人: Grail, LLC
IPC分类号: C12Q1/6869 , C12Q1/6886 , G16B20/00 , G16B40/00 , G16B40/20 , G16H50/20
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公开(公告)号:EP4073804A1
公开(公告)日:2022-10-19
申请号:EP20829148.4
申请日:2020-12-11
申请人: Grail, LLC
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