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公开(公告)号：EP1283035A3
公开(公告)日：2003-03-19
申请号：EP02025764.8
申请日：1995-12-08
Applicant: AstraZeneca AB
Inventor： Bäckstrom, Kjell , Wallmark, Björn
CPC classification number: A61K9/0075 , A61K38/29 , A61K47/12 , Y10S514/826
Abstract: The present invention relates to compositions and methods for pulmonary administration of full-length parathyroid hormone to mammalian hosts for the treatment of osteoporosis. Thus there is provided a therapeutic, dry powder preparation suitable for inhalation comprising (i) as an active substance, a parathyroid hormone having an amino acid sequence which is at least 90% homologous to the sequence shown as SEQ ID NO: 1 in the Sequence Listing having the biological activities of the full-length parathyroid hormone; (ii) a pharmaceutically acceptable carrier consisting of coarse particles; and, optionally, (iii) as an active substance, a substance which enhances the absorption of parathyroid hormone in the lower respiratory tract; wherein an ordered mixture is formed between said active compound(s) and the carrier; in which at least 50% of the total mass of the active substance parathyroid hormone consists of (a) particles having a diameter of up to 10 microns; or (b) agglomerates of such particles.
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公开(公告)号：EP0911026B1
公开(公告)日：2003-03-12
申请号：EP98202219.6
申请日：1998-07-01
Applicant: Uchida, Yoshiyuki , Immuno- BioJapan Co., Ltd.
Inventor： Uchida, Yoshiyuki , Sueoka, Haruhiko
IPC: A61K31/195 , A61P11/06
CPC classification number: A61K31/195 , Y10S514/826
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公开(公告)号：EP1267866A2
公开(公告)日：2003-01-02
申请号：EP01966751.8
申请日：2001-04-09
Applicant: Arakis Limited
Inventor： BANNISTER, Robin Mark,Arakis Ltd. , RICHARDS, Andrew John McGlashan , GILBERT, Julian Clive,Arakis Ltd. , MORTON, David A., V.,Vectura Limited , STANIFORTH, JohnVectura Limited
IPC: A61K31/40
CPC classification number: A61K9/0075 , A61K9/145 , A61K31/00 , A61K31/40 , A61K31/46 , A61K45/06 , Y10S514/826 , Y10S514/851 , A61K2300/00
Abstract: A pharmaceutical composition for pulmonary delivery comprises glycopyrrolate in a controlled release formulation, wherein, on administration, the glycopyrrolate exerts its pharmacological effect over a period greater than 12 hours.
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公开(公告)号：EP0828727B1
公开(公告)日：2003-01-02
申请号：EP96914207.4
申请日：1996-05-14
Applicant: ALTANA Pharma AG
Inventor： AMSCHLER, Hermann , BÄR, Thomas , FLOCKERZI, Dieter , SCHMID, Beate , THIBAUT, Ulrich , HATZELMANN, Armin , BOSS, Hildegard , HÄFNER, Dietrich , KLEY, Hans-Peter , BEUME, Rolf , ULRICH, Wolf-Rüdiger , MARTIN, Thomas
IPC: C07D307/94 , C07D307/86 , A61K31/34
CPC classification number: C07D307/94 , C07D307/86 , Y10S514/826 , Y10S514/886 , Y10S514/889 , Y10S514/914
Abstract: Compounds having the formula (I), in which R1, R2, R3, R4 and R5 have the meanings given in the description, are new powerful PDE inhibitors.
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公开(公告)号：EP1082108B1
公开(公告)日：2002-12-18
申请号：EP98955794.7
申请日：1998-11-26
Applicant: BRITANNIA PHARMACEUTICALS LIMITED
Inventor： HILLS, Brian, Andrew , WOODCOCK, Derek, Alan
IPC: A61K31/00 , A61K31/685 , A61K31/683 , A61M15/00 , A61P11/06
CPC classification number: A61M11/02 , A61M11/001 , A61M11/002 , A61M15/00 , A61M2205/8225 , Y10S514/826 , Y10S514/958 , Y10S514/959
Abstract: A method and apparatus is disclosed for treating asthma and other respiratory conditions. A medicament comprising a surface active phospholipid (SAPL) is prepared in the form of a fine powder and administered to the lungs in a gas stream. A preferred SAPL is a solid blend of dipalmitoyl phosphatidyl choline (DPPC) and phosphatidyl glycerol (PG).
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Patent Agency Ranking
公开(公告)号：EP0653205B1
公开(公告)日：2002-10-16
申请号：EP95101762.3
申请日：1992-06-08
Applicant: SCHERING CORPORATION
Inventor： Berry, Julianne , Chaudry, Imtiaz A. , Sequeira, Joel A. , Kopcha, Michael
CPC classification number: A61K9/008 , A61K9/124 , A61K31/573 , A61K31/58 , C09K3/30 , Y10S514/826
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37.发明公开
公开(公告)号：EP1212049A2
公开(公告)日：2002-06-12
申请号：EP01940275.9
申请日：2001-04-02
Applicant: ZAMBON GROUP S.p.A.
Inventor： COLOMBO, Giovanni,Battista , UNGHERI, Domenico , LICCIARDELLO, Luciano , GISMONDO, Maria,Rita , DRAGO, Lorenzo
IPC: A61K31/165 , A61P31/04
CPC classification number: A61K31/165 , Y10S514/826
Abstract: Use of thiamphenicol and derivatives thereof for the preparation of pharmaceutical compositions useful for the treatment of Chlamydia pneumoniae infections is described.
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公开(公告)号：EP1156800A1
公开(公告)日：2001-11-28
申请号：EP00915968.2
申请日：2000-03-01
Applicant: SMITHKLINE BEECHAM CORPORATION
Inventor： NIEMAN, Richard , TORPHY, Theodore , CHRISTENSEN, Siegfried
IPC: A61K31/275 , A01N43/64 , A01N43/82
CPC classification number: A61K31/00 , A61K31/275 , Y10S514/826
Abstract: Methods of treating exercise-induced asthma using a PDE4 inhibitor are disclosed.
Abstract translation: 公开了使用PDE4抑制剂治疗运动诱导的哮喘的方法。
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39.发明公开
公开(公告)号：EP1147011A1
公开(公告)日：2001-10-24
申请号：EP99963991.7
申请日：1999-11-24
CPC classification number: A61K38/212 , Y10S514/826 , Y10S514/851
Abstract: A method for enhancing the expression of aquaporin proteins by contacting aquaporin producing cells with interferon-α is described. The method enables treatment of patients afflicted with disease states characterized by xerosis.
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40.发明公开Method for denaturing allergens using calcium or strontium salts 有权Verfahren zum Denaturieren von Allergenen unter Verwendung von Calcium-oder Strontiumsalzen
公开(公告)号：EP1133918A1
公开(公告)日：2001-09-19
申请号：EP01105419.4
申请日：2001-03-12
Applicant: Sumitomo Chemical Co.,Ltd. , Shinto Fine Co., Ltd.
Inventor： Inui, Keiichiro , Mikame, Mariko
CPC classification number: A01N59/16 , A01N59/06 , A01N59/08 , Y10S514/826 , A01N59/26 , A01N37/36 , A01N37/04 , A01N31/08 , A01N2300/00
Abstract: Application of an alkaline earth metal salt selected from calcium and strontium salts can steadily denature the allergens those exist in the environment without any coloring trouble on the treated material.
Abstract translation: 使用选自钙和锶盐的碱土金属盐可以稳定地使存在于环境中的过敏原变性，而在处理过的材料上没有任何着色问题。
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