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公开(公告)号：EP3911716B1
公开(公告)日：2022-09-21
申请号：EP20700398.9
申请日：2020-01-15
IPC分类号： C09K11/06 , H01L51/50 , C07C13/567 , C07D307/91 , C07D317/70 , C07D493/04
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32.发明公开
公开(公告)号：EP4050004A1
公开(公告)日：2022-08-31
申请号：EP20892802.8
申请日：2020-09-15
申请人： INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES , Changchun Intellicrown Pharmaceutical Co., Ltd.
发明人： WU, Song , SUN, Hua , ZHANG, Jinlan , ZHANG, Wenxuan , WANG, Zhe , YANG, Qingyun , JIANG, Lin , CHEN, Zihan , SHEN, Jing , ZHANG, Jie , ZHANG, Chi , HAN, Zunsheng , QIN, Tong , ZHANG, Yuanyuan
IPC分类号： C07D317/68 , A61K31/5377 , A61P1/16 , A61P31/14 , A61P31/20 , A61P37/02
摘要： The invention relates to the field of pharmaceutical chemistry, and it particularly relates to a left-handed bicyclic morpholine and a pharmaceutically acceptable salt thereof, a preparation method therefor, a pharmaceutical composition and use thereof in the preparation of medicaments for preventing and/or treating liver diseases and the like.
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公开(公告)号：EP4048652A1
公开(公告)日：2022-08-31
申请号：EP20797886.7
申请日：2020-10-22
发明人： CROCKATT, Marc
IPC分类号： C07C37/56 , C07C45/52 , C07C45/59 , C07C51/16 , C07D307/46 , C07D307/89 , C07D317/70 , C07C63/00 , C07C47/52 , C07C39/02 , C07C39/00
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公开(公告)号：EP4026831A1
公开(公告)日：2022-07-13
申请号：EP20860373.8
申请日：2020-09-01
发明人： WU, Hongfei , XU, Jingbo , LIU, Shaowu , YU, Haibo , BAN, Lanfeng , XU, Libao , CHENG, Xueming , GUO, Chunxiao , SUN, Ningning
IPC分类号： C07D317/46 , A01N43/30
摘要： The present invention belongs to the fields of insecticides and acaricides, and particularly relates to a piperonylic acid derivative and application thereof. The structure is shown in a general formula I, and the definition of each substituent in the formula is described in the description. The compound of the general formula I has excellent insecticidal and acaricidal activity and can be used for controlling various pests and mites.
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公开(公告)号：EP4025315A1
公开(公告)日：2022-07-13
申请号：EP20761611.1
申请日：2020-09-01
发明人： BLACK, Jesse, Raymond , BASTINGS, Roel, Guillaume, Hubertus, Leonardus , DEKKERS, Mark, Albert, Petrus
IPC分类号： B01D3/14 , B01D3/42 , C07C29/10 , C07D317/38 , C07C31/20
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36.发明公开
公开(公告)号：EP4003971A1
公开(公告)日：2022-06-01
申请号：EP20780327.1
申请日：2020-07-27
申请人： ARKEMA FRANCE
发明人： NUNEZ, Sean , SNOW, Kyle
IPC分类号： C07D317/36 , C08F20/28
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公开(公告)号：EP3983381A1
公开(公告)日：2022-04-20
申请号：EP20733711.4
申请日：2020-06-12
申请人： Arxada AG
发明人： TAESCHLER, Christoph , BELLER, Matthias , NEUMANN, Helfried , FISCHER, Florian , ZHANG, Shaoke , YE, Fei , ELLINGER, Stefan , ZARAGOZA DOERWALD, Florencio
IPC分类号： C07D207/06 , C07D211/12 , C07D223/04 , C07D265/30 , C07D317/72
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公开(公告)号：EP3983363A1
公开(公告)日：2022-04-20
申请号：EP20744153.6
申请日：2020-06-17
IPC分类号： C07C13/263 , C07D317/44 , A61K47/54
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公开(公告)号：EP3932914A1
公开(公告)日：2022-01-05
申请号：EP21169630.7
申请日：2016-03-11
申请人： Valo Health, Inc.
发明人： BAIR, Kenneth W. , BARCZAK, Nicholas , HAN, Bingsong , LANCIA, David R., Jr. , LIU, Cuixian , MARTIN, Matthew W. , NG, Pui Yee , RUDNITSKAYA, Aleksandra , THOMASON, Jennifer R. , ZABLOCKI, Mary-Margaret , ZHENG, Xiaozhang
IPC分类号： C07D401/14 , C07D213/75 , C07C259/06 , A61P35/00 , C07D213/81 , C07D215/12 , C07C275/30 , C07D317/68 , C07D231/14 , C07D231/18 , C07D233/36 , C07D233/38 , C07D333/70 , C07D233/68 , C07D401/04
摘要： The present invention relates to inhibitors of histone deacetylases, in particular HDAC8, that are useful for the treatment of cancer and other diseases and disorders, as well as the synthesis and applications of said inhibitors.
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