公开(公告)号：EP3494109B1

公开(公告)日：2024-10-23

申请号：EP17749168.5

申请日：2017-07-31

发明人： HIMMLER, Thomas ,  HAHN, Julia, Johanna ,  CREDE, Joachim

IPC分类号： C07D317/72

公开(公告)号：EP3774761B1

公开(公告)日：2024-09-11

申请号：EP19715090.7

申请日：2019-04-03

IPC分类号： C07D317/72 ,  C07C229/48 ,  C07D491/10 ,  C07D498/10 ,  C07C233/52

CPC分类号： C07C229/48 ,  C07C233/52 ,  C07C2601/1420170501 ,  C07D317/72 ,  C07D491/10 ,  C07D498/10

公开(公告)号：EP3757090B1

公开(公告)日：2024-06-12

申请号：EP20177336.3

申请日：2009-11-10

IPC分类号： C07D317/46 ,  A61K31/713 ,  A61P33/00 ,  A61K9/127 ,  A61K31/7088 ,  A61P37/04 ,  C07D203/10 ,  C07D317/28 ,  C07D317/44 ,  C07D405/12 ,  C07D317/72 ,  C07D491/056 ,  A61K39/00 ,  A61P35/00 ,  C07D319/06 ,  C07D491/113 ,  C12N15/11

CPC分类号： A61K39/00 ,  C12N15/111 ,  A61K9/1272 ,  A61K31/713 ,  C07D319/06 ,  C07D317/28 ,  C07D203/10 ,  A61K31/7088 ,  C07D317/44 ,  C07D317/46 ,  C07D317/72 ,  C07D405/12 ,  C07D491/056 ,  C07D491/113 ,  A61P33/00 ,  A61P35/00 ,  A61P37/04 ,  Y02A50/30

公开(公告)号：EP4316486A1

公开(公告)日：2024-02-07

申请号：EP22781424.1

申请日：2022-03-10

申请人： Hyundai Pharm Co., Ltd.

发明人： YOO, Hye Jin ,  HWANG, Hwan Jin

IPC分类号： A61K31/357 ,  A61P21/00 ,  C07D317/72

摘要： A 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative according to the present invention promotes the expression of the myogenic factors MyoG and MyHC while inhibiting the expression of the muscle atrophy factor atrogin-1, promotes the formation of myotubes, and inhibits myocyte apoptosis, and thus can promote myogenesis and inhibit muscle atrophy.

公开(公告)号：EP3983381A1

公开(公告)日：2022-04-20

申请号：EP20733711.4

申请日：2020-06-12

申请人： Arxada AG

发明人： TAESCHLER, Christoph ,  BELLER, Matthias ,  NEUMANN, Helfried ,  FISCHER, Florian ,  ZHANG, Shaoke ,  YE, Fei ,  ELLINGER, Stefan ,  ZARAGOZA DOERWALD, Florencio

IPC分类号： C07D207/06 ,  C07D211/12 ,  C07D223/04 ,  C07D265/30 ,  C07D317/72

公开(公告)号：EP3904321A1

公开(公告)日：2021-11-03

申请号：EP19902614.7

申请日：2019-12-26

申请人： M. Technique Co., Ltd.

发明人： ENOMURA Masakazu ,  ENDO Takeshi ,  TAKEDA Kazutaka

IPC分类号： C07C27/00 ,  C07C27/02 ,  C07C29/12 ,  C07C31/10 ,  C07C31/12 ,  C07C31/125 ,  C07C45/74 ,  C07C69/12 ,  C07C69/18 ,  C07C69/602 ,  C07D317/72 ,  C07C49/217 ,  C07C49/255 ,  B01J19/18 ,  C07C67/08 ,  C07C67/343

摘要： Provided is a method for producing an organic compound, the method making it possible to ensure an adequate reaction time and obtain a targeted substance at a high yield even in an organic reaction that requires a relatively long time to complete the reaction. A method for producing an organic compound, wherein the method is characterized in that: a fluid processing apparatus F used in the production method is equipped with an upstream processing unit that processes a fluid to be processed between at least two processing surfaces 1 and 2 that relatively rotate, and a downstream processing unit disposed downstream of the upstream processing unit, the downstream processing unit being provided with a plurality of labyrinth seals that function to retain and stir the fluid to be processed that has been processed by the upstream processing unit; due to the fluid to be processed, which contains at least one type of organic compound, being passed through the upstream processing unit, the fluid to be processed is subjected to upstream processing; due to the fluid to be processed that has been subjected to upstream processing being passed through the downstream processing unit, the fluid to be processed that has been subjected to upstream processing is subjected to downstream processing; and the upstream processing and the downstream processing are performed continuously.

公开(公告)号：EP3564226B1

公开(公告)日：2021-06-02

申请号：EP17885459.2

申请日：2017-12-26

发明人： AOKI, Takashi

IPC分类号： C07D317/32 ,  C07D317/72 ,  C07C51/09 ,  C07C59/10 ,  C07C67/31 ,  C07C69/675

公开(公告)号：EP3774721A1

公开(公告)日：2021-02-17

申请号：EP19713064.4

申请日：2019-03-29

申请人： Heidelberg Pharma Research GmbH ,  Corden Pharma International GmbH

发明人： KNITTEL, Caroline ,  SIEGERT, Mary-Ann ,  SÜSSMUTH, Roderich ,  WINK, Christoph ,  JAS, Gerhard

IPC分类号： C07C231/12 ,  C07C233/47 ,  C07C269/04 ,  C07C269/06 ,  C07C271/22 ,  C12P13/04 ,  C07D301/03 ,  C07D303/40 ,  C07D317/20 ,  C07D317/72 ,  C07D319/20 ,  C07D493/10 ,  C07D493/20 ,  C07F7/18

公开(公告)号：EP3271344B1

公开(公告)日：2020-08-26

申请号：EP16801801.8

申请日：2016-11-29

申请人： F.I.S.- Fabbrica Italiana Sintetici S.p.A.

发明人： MARAGNI, Paolo ,  VERZINI, Massimo

IPC分类号： C07D309/14 ,  C07D317/28 ,  C07C215/00 ,  C07D303/36 ,  C07C309/00 ,  C07C233/00 ,  C07C233/18 ,  C07C271/16 ,  C07C309/73 ,  C07D317/72

公开(公告)号：EP3443959A1

公开(公告)日：2019-02-20

申请号：EP18194547.8

申请日：2014-12-12

申请人： Bio-Pharm Solutions Co., Ltd.

发明人： CHOI, Yong Moon

IPC分类号： A61K31/357 ,  A61K31/381 ,  A61K31/427 ,  A61K31/443 ,  A61K31/506 ,  C07D317/24 ,  C07D317/36 ,  C07D317/72 ,  C07D405/04 ,  C07D409/04 ,  C07D417/04 ,  A61P29/02

摘要： The present invention relates to sulfamate derivative compounds and a composition for treating and/or alleviating pain containing the sulfamate derivative compounds or a pharmaceutically acceptable salt thereof as an active ingredient. More specifically, the present invention relates to a pharmaceutical composition for treating or alleviating pain containing a sulfamate derivative compound and/or a pharmaceutically acceptable salt thereof as an active ingredient. Furthermore, the present invention relates to a method for treatment or alleviation of pain comprising administering a sulfamate derivative compound in a pharmaceutically effective amount to a subject in need of treatment or alleviation of pain; and a use of the sulfamate derivative compound or the pharmaceutically acceptable salt thereof in treating and/or alleviating pain, are provided.