公开(公告)号：EP0666771B1

公开(公告)日：2000-08-23

申请号：EP94917252.2

申请日：1994-02-14

申请人： BAXTER INTERNATIONAL INC.

发明人： BROWN, Richard, I.

IPC分类号： B01D37/00 ,  B01D61/00 ,  B01D21/26 ,  B01D21/30 ,  A61M1/00

CPC分类号： B04B13/00 ,  A61M1/30 ,  A61M1/302 ,  A61M1/303 ,  A61M1/3693 ,  A61M1/3696 ,  A61M2202/0427 ,  B01D17/0217 ,  B01D21/2405 ,  B01D21/245 ,  B01D21/26 ,  B01D21/262 ,  B01D21/34 ,  B01D2221/08 ,  B01D2221/10 ,  B04B5/0442 ,  A61M2202/0071

摘要： Systems and methods for collecting cellular-rich concentrates of blood are disclosed. Blood from donor (78) is mixed with anticoagulant (90) and conveyed to a first separation device (12) for separating an anticoagulated cellular suspension from blood. The anticoagulated cellular suspension is conveyed to a second separation device (14) for removing leukocytes. Leukocyte-depleted cellular suspension is conveyed to a third separation device (16) for concentrating the leukocyte-depleted cellular suspension into a cellular-rich concentrate and a cellular-poor component and a portion of the cellular-poor component is returned to the donor (78). A controller (88) is used to control the process including monitoring the rate at which anticoagulant carried in the cellular-poor component is being infused with the returned cellular-poor component into the donor (78).

公开(公告)号：EP0662857B1

公开(公告)日：1999-04-07

申请号：EP94913269.0

申请日：1994-02-14

申请人： BAXTER INTERNATIONAL INC.

发明人： BROWN, Richard, I.

IPC分类号： B01D36/00 ,  B01D37/00 ,  B01D61/00 ,  A61M1/36 ,  B04B15/00

CPC分类号： B01D21/302 ,  A61M1/0218 ,  A61M1/30 ,  A61M1/302 ,  A61M1/303 ,  A61M1/3693 ,  A61M1/3696 ,  A61M2202/0427 ,  B01D21/262 ,  B01D2221/08 ,  B01D2221/10 ,  B04B5/0442 ,  A61M2202/0071

公开(公告)号：EP0882464A3

公开(公告)日：1999-03-10

申请号：EP98202858.1

申请日：1994-02-14

申请人： BAXTER INTERNATIONAL INC.

发明人： Brown, Richard I.

IPC分类号： A61M1/36 ,  B01D21/26

CPC分类号： B01D21/302 ,  A61M1/0218 ,  A61M1/30 ,  A61M1/302 ,  A61M1/303 ,  A61M1/3693 ,  A61M1/3696 ,  A61M2202/0427 ,  B01D21/262 ,  B01D2221/08 ,  B01D2221/10 ,  B04B5/0442 ,  A61M2202/0071

摘要： Whole blood is separated in a separation chamber (12) into a red blood cell layer (RBC) and a platelet rich plasma (PRP) layer. A portion of the PRP layer is conveyed along an outlet path (108) to a leukocyte filter (14), which removes leukocytes from the PRP. The remaining portion of the PRP is conveyed along a bypass path (112), which bypasses the filter (14), to be mixed with the whole blood being conveyed to the separation chamber (12). A controller (88) controls flow in the bypass path (112) to maintain a predetermined surface hematocrit of the blood entering the separation chamber (12). The arrangement improves RBC/PRP separation and improves leukocyte removal by the filter (14).

公开(公告)号：EP0666771A4

公开(公告)日：1998-09-16

申请号：EP94917252

申请日：1994-02-14

申请人： BAXTER INT

发明人： BROWN RICHARD I

IPC分类号： A61M1/02 ,  A61K35/14 ,  A61M1/30 ,  A61M1/36 ,  B01D17/02 ,  B01D21/24 ,  B01D21/26 ,  B01D21/30 ,  B01D37/00 ,  B04B5/04 ,  B04B13/00 ,  A61M1/00 ,  B01D61/00

CPC分类号： B04B13/00 ,  A61M1/30 ,  A61M1/302 ,  A61M1/303 ,  A61M1/3693 ,  A61M1/3696 ,  A61M2202/0427 ,  B01D17/0217 ,  B01D21/2405 ,  B01D21/245 ,  B01D21/26 ,  B01D21/262 ,  B01D21/34 ,  B01D2221/08 ,  B01D2221/10 ,  B04B5/0442 ,  A61M2202/0071

摘要： Systems and methods for collecting cellular-rich concentrates of blood are disclosed. Blood from donor (78) is mixed with anticoagulant (90) and conveyed to a first separation device (12) for separating an anticoagulated cellular suspension from blood. The anticoagulated cellular suspension is conveyed to a second separation device (14) for removing leukocytes. Leukocyte-depleted cellular suspension is conveyed to a third separation device (16) for concentrating the leukocyte-depleted cellular suspension into a cellular-rich concentrate and a cellular-poor component and a portion of the cellular-poor component is returned to the donor (78). A controller (88) is used to control the process including monitoring the rate at which anticoagulant carried in the cellular-poor component is being infused with the returned cellular-poor component into the donor (78).

公开(公告)号：EP0572656B1

公开(公告)日：1997-11-05

申请号：EP93902747.0

申请日：1992-12-23

申请人： BAXTER INTERNATIONAL INC.

发明人： WILLIAMSON, Warren, P., IV ,  BROWN, Richard, I.

IPC分类号： B04B7/08 ,  B04B5/04

CPC分类号： B04B13/00 ,  A61M1/30 ,  A61M1/302 ,  A61M1/303 ,  A61M1/308 ,  A61M1/3693 ,  A61M1/3696 ,  A61M2202/0427 ,  A61M2205/3344 ,  A61M2205/3351 ,  A61M2205/3355 ,  B01D17/0217 ,  B01D21/0003 ,  B01D21/2405 ,  B01D21/245 ,  B01D21/26 ,  B01D21/262 ,  B01D2221/08 ,  B01D2221/10 ,  B04B5/0442 ,  B04B7/08 ,  B04B2005/045 ,  A61M2202/0071

摘要： A centrifuge provides simplify access to the processing chamber. In one arrangement, the processing chamber separates into a bowl and spool element to receive a disposable processing bag. In another arrangement, the processing chamber pivots between an operating position and an access position to provide improved access. The centrifuge also employs readily accessible holders for releasably retaining tubing that, in use, conveys fluid to and from the chamber. Though greatly accessible, the centrifuge operates without the need of complicated rotating seals and expensive disposable components.

公开(公告)号：EP0666770A1

公开(公告)日：1995-08-16

申请号：EP94916495.0

申请日：1994-02-14

申请人： BAXTER INTERNATIONAL INC.

发明人： BROWN, Richard, I.

IPC分类号： A61M1 ,  A61K35 ,  B01D21 ,  B04B5

CPC分类号： B04B5/0442 ,  A61M1/30 ,  A61M1/302 ,  A61M1/303 ,  A61M1/3693 ,  A61M1/3696 ,  A61M2202/0427 ,  B01D21/262 ,  B01D21/302 ,  B01D2221/08 ,  B01D2221/10 ,  B04B2005/045 ,  A61M2202/0071

摘要： Systems and methods for resuspending cellular-rich concentrates of blood are disclosed. Systems include first compartment (24) including a blood inlet port (40) and a plasma-rich platelets (PRP) collection port (38) and a red blood cell collection port (42), and second compartment (26) including a platelet-poor plasma (PPP) collection port (44) and a leukocyte-depleted PRP (LDPRP) inlet port (46), and a separation element (14). In resuspension mode, a volume of retained PPP is returned through the PPP collection port (44) into the second compartment (26) to mix with and resuspend leukocyte-depleted platelet concentrate (LDPC) in the second compartment (26). During the resuspension period, a rotor (28) slowly oscillates the second compartment (26) first in one rotational direction and then in an opposite rotational direction. The oscillation creates variable agitation forces that aid the mixing and resuspension process within the second compartment (26).

摘要翻译： 系统和方法通过摇动分离室来重新悬浮富含细胞的血液浓缩物，以在分离室内产生可变的搅动力。 系统和方法还加入重悬浮液以帮助重悬浮。

公开(公告)号：EP0572656A4

公开(公告)日：1994-12-14

申请号：EP93902747

申请日：1992-12-23

申请人： BAXTER INT

发明人： WILLIAMSON WARREN P IV ,  BROWN RICHARD I

IPC分类号： B04B5/00 ,  A61M1/30 ,  A61M1/36 ,  B01D17/02 ,  B01D21/24 ,  B01D21/26 ,  B04B5/04 ,  B04B7/08 ,  B04B13/00

CPC分类号： B04B13/00 ,  A61M1/30 ,  A61M1/302 ,  A61M1/303 ,  A61M1/308 ,  A61M1/3693 ,  A61M1/3696 ,  A61M2202/0427 ,  A61M2205/3344 ,  A61M2205/3351 ,  A61M2205/3355 ,  B01D17/0217 ,  B01D21/0003 ,  B01D21/2405 ,  B01D21/245 ,  B01D21/26 ,  B01D21/262 ,  B01D2221/08 ,  B01D2221/10 ,  B04B5/0442 ,  B04B7/08 ,  B04B2005/045 ,  A61M2202/0071

摘要： A centrifuge provides simplify access to the processing chamber. In one arrangement, the processing chamber separates into a bowl and spool element to receive a disposable processing bag. In another arrangement, the processing chamber pivots between an operating position and an access position to provide improved access. The centrifuge also employs readily accessible holders for releasably retaining tubing that, in use, conveys fluid to and from the chamber. Though greatly accessible, the centrifuge operates without the need of complicated rotating seals and expensive disposable components.

公开(公告)号：EP0030957A1

公开(公告)日：1981-07-01

申请号：EP80901243.0

申请日：1980-06-04

申请人： AVCO CORPORATION

发明人： LIBERTINI, Zoltan L.

IPC分类号： B01D33 ,  B01D21 ,  B04B1 ,  B04B3 ,  B04B5

CPC分类号： B04B5/06 ,  B01D21/0012 ,  B01D21/26 ,  B01D21/262 ,  B01D2221/08 ,  B04B1/04 ,  B04B5/005 ,  Y10S494/901

摘要： A centrifugal oil filter for removing contaminant particles from a pressurized fluid medium includes a cylindrical drum concentric with and fixedly secured to a rotational shaft, with an annular disc being disposed within and rotatable with the drum. The disc is centered within the drum and spaced from the internal circumferential surface of the drum so as to partition the drum into two radial passageways interconnected at said internal circumferential surface. The latter is of irregular configuration to define an annular collection zone for collecting contaminant particles centerfuged outwardly by rotation of said drum. Pressurized fluid medium is provided to one radial passageway, flows past the annular collection zone where the contaminant particles are centerfuged and entrapped in the irregular internal circumferential surface of the drum, after which the pressurized fluid medium is forced radially inwardly through the other radial passageway and out of the centrifugal oil filter.

公开(公告)号：EP0026417A2

公开(公告)日：1981-04-08

申请号：EP80105661.5

申请日：1980-09-20

申请人： Firma Andreas Hettich

发明人： Eberle, Günter

IPC分类号： A61M1/03 ,  B04B5/02 ,  B01D21/26

CPC分类号： A61M1/3693 ,  A61M1/0209 ,  A61M1/3698 ,  B01D21/262 ,  B01D21/34 ,  B01D2221/08 ,  B01D2221/10 ,  B04B5/0428

摘要： Ein Zentrifugenbecher (2) einer Zentrifuge weist zwei Kammern (1,3) auf. In der ersten Kammer (1) ist der mit Blutflüssigkeit gefüllte erste Blutbeutel (6) eingesetzt, der zusammen in die Kammer mit einem elastisch verformbaren Einsatzbecher (4) eingesetzt ist. Ein Druckkissen (9) liegt einerseits an der Außenseite (7) des Einsatzbechers (4) und andererseits an der Innenseite (8) der Kammer (1) der Zentrifuge. Während des Zentrifugiervorganges wird das Druckkissen (9) mit Druck beaufschlagt, so daß eine starke Volumenzunahme die Folge ist. Hierdurch wird der Einsatzbecher (4) elastisch zusammengedrückt, wordurch der Blutbeutel (6) komprimiert wird und die in dem Blutbeutel abzentrifugierten Blutbestandteile entsprechend der Volumenzunahme des Druckkissens (9) in einen in der benachbarten Kammer (2) angeordneten leeren Satelliten-Blutbeutel übergeführt werden. Auf den oberen, aus der Kammer (1) herausragenden Anschlußteil (81) des Blutbeutels ist ein Halterungsteil (64) aufgeschoben, das ein Umknicken der Anschlußschläuche während des Zentrifugiervorganges verhindert.

摘要翻译： 离心机的杯子（2）具有两个腔室（1,3）。 在第一室中放置充满血液的第一血袋（6），其与可弹性变形的插入杯（4）一起插入腔室中。 压力垫（9）在插入杯（4）的外侧（7）的一端和离心机的室（1）的内侧（8）的另一端承载。 在离心过程中，压力垫（9）承受压力，导致大量的体积增加。 插入杯（4）因此被弹性地压缩，使得血袋（6）被压缩，并且将血袋中离心的血液成分相应于压力垫（9）的体积增加转移到空的卫星血袋 布置在相邻的室（2）中。 在从腔室（1）突出的血液袋的上部连接部分（81）上被推动，以防止在离心过程中连接管弯曲的保持器（64）。

公开(公告)号：EP3085911A1

公开(公告)日：2016-10-26

申请号：EP15164659.3

申请日：2015-04-22

申请人： Wärtsilä Moss AS

发明人： Gannefors, Jan Gunnar ,  Clausen, Per

IPC分类号： F01N3/04 ,  F01N13/00

CPC分类号： F01N3/04 ,  B01D47/06 ,  B01D2221/08 ,  B01D2247/04 ,  F01N13/0093 ,  F01N13/0097 ,  F01N2490/08 ,  F01N2590/02 ,  Y02T10/20

摘要： The present invention is a method for dual water scrubbing and an in-line dual water scrubber for gas cleaning onboard a vessel and comprising a vertical extended body, a gas inlet, a gas outlet,
- the gas inlet is underlying in the lower section of the extended body and the gas outlet is overlying in the upper section of the extended body,
further comprising a first underlying scrubbing section,
a second scrubbing section in upper section of the extended body, -one or more liquid collectors arranged above one or more first scrubbing liquid spray means, the liquid collector arranged for collecting one or more second scrubbing liquid and for flow through of a vertical upwards flowing gas-flow from the inlet to the outlet.

摘要翻译： 本发明是用于双重水洗涤的方法和用于在容器上进行气体清洁的直列双重水洗涤器，并且包括垂直延伸体，气体入口，气体出口， - 气体入口位于下部的下部 延伸体和气体出口在延伸体的上部中覆盖，还包括第一下部擦洗部分，在延伸体的上部中的第二洗涤部分， - 一个或多个液体收集器，其布置在一个或多个第一 洗涤液体喷射装置，液体收集器被布置成用于收集一个或多个第二洗涤液体并且用于从入口到出口的垂直向上流动的气体流的流动。