Production and use of genetically-modified microorganisms
    44.
    发明公开
    Production and use of genetically-modified microorganisms 失效
    遗传改良微生物的生产和使用

    公开(公告)号:EP0066994A3

    公开(公告)日:1984-02-01

    申请号:EP82302608

    申请日:1982-05-21

    摘要: The genetic modification of microorganisms which can be grown upon methanol as a carbon source to produce single cell protein (SCP). By the modification the genes specifying the methanol oxidase (MO) and methanol dehydrogenase (MDH) enzymes, used in the normal metabolic pathways by which the microorganisms convert methanol to formaldehyde, are replaced by adh genes capable of expressing an alcohol dehydrogenase (ADH) enzyme catalyst for the oxidation of methanol to formaldehyde. The modified microorganism has increased energetic efficiency in utilizing carbon. Preferably the modified microorganism is derived from Methyiophilus methylotrophus. The claims cover genetically modified microorganisms, a method of making genetically modified microorganisms and a process for the production of single cell protein.