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41.发明授权METHOD TO SPORULATE COCCIDIAL OOCYSTS PURIFIED FROM ANIMAL FAECES, SPORULATED OOCYSTS OBTAINED WITH THIS METHOD AND A VACCINE CONTAINING THESE SPORULATED OOCYSTS 有权使用本方法获得的动物精液，经过滤的卵母细胞以及含有这些孢子母细胞的疫苗纯化的兽药卵母细胞的方法
公开(公告)号：EP3126488B1
公开(公告)日：2018-01-24
申请号：EP15714489.0
申请日：2015-04-02
CPC分类号： C12N3/00 , A61K39/012 , C12M27/10 , C12M33/14 , C12N1/10
摘要： The invention pertains to a method to sporulate coccidial oocysts purified from animal faeces (5), the method comprising providing the purified oocysts as a layer (40) on a supporting surface (22), maintaining the layer at least intermittently in an oxygen containing gaseous environment (60) having a relative humidity of at least 15% and maintaining the temperature of the oocysts between 19° C. and 37° C. The invention also pertains to sporulated oocysts obtained with this method and to a vaccine containing such sporulated oocysts.
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公开(公告)号：EP3104883A4
公开(公告)日：2017-08-23
申请号：EP15749196
申请日：2015-02-11
申请人： THE STATE OF ISRAEL MINI OF AGRICULTURE & RURAL DEV KIMRON VETERINARY INST , RAMOT AT TEL AVIV UNIV LTD
发明人： BACHARACH ERAN , ELDAR AVI
CPC分类号： A61K39/12 , A61K9/0014 , A61K9/0019 , A61K9/0056 , A61K2039/5254 , A61K2039/552 , C12N7/00 , C12N2760/00 , C12N2760/00011 , C12N2760/00021 , C12N2760/00022 , C12N2760/00034
摘要： The present invention relates to vaccine compositions comprising attenuated strain of Tilapia Lake Virus (TiLV) for protecting tilapia fish against infection by (TiLV). The invention also relates to methods for using the vaccines to protect tilapines from TiLV-induced disease.
摘要翻译： 本发明涉及包含用于保护罗非鱼鱼免于（TiLV）感染的罗非鱼病毒（TiLV）减毒株的疫苗组合物。 本发明还涉及使用疫苗来保护罗非鱼免受TiLV诱导的疾病的方法。
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43.发明公开COMPOSITIONS AND METHODS OF ENHANCING IMMUNE RESPONSES TO EIMERIA 审中-公开ZUSAMMENSETZUNGEN UND VERFAHREN ZURVERSTÄRKUNGVON IMMUNREAKTIONENGEGENÜBEREIMERIA
公开(公告)号：EP3097926A1
公开(公告)日：2016-11-30
申请号：EP16175274.6
申请日：2008-11-03
申请人： The Board of Trustees of the University of Arkansas , The Texas A&M University System , University of Guelph
发明人： BOTTJE, Walter , HARGIS, Billy , BERGHMAN, Luc , KWON, Young, Min , COLE, Kimberly , COX, Mandy , LAYTON, Sherryll , EL-ASHRAM, Saeed , BARTA, John , TELLEZ, Guillermo
IPC分类号： A61K39/012 , A61K38/04
摘要： Vaccines comprising TRAP polypeptides and Salmonella enteritidis vectors comprising TRAP polypeptides are provided. The vaccines may also include a CD 154 polypeptide capable of binding to CD40. Also provided are methods of enhancing an immune response against Apicomplexan parasites and methods of reducing morbidity associated with infection with Apicomplexan parasites.
摘要翻译： 提供包含TRAP多肽和包含TRAP多肽的肠炎沙门氏杆菌载体的疫苗。 疫苗还可以包括能够结合CD40的CD154多肽。 还提供了增强针对Apicomplexan寄生虫的免疫应答的方法和降低与Apicomplexan寄生虫感染相关的发病率的方法。
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44.发明授权
公开(公告)号：EP2531214B1
公开(公告)日：2016-08-31
申请号：EP11704289.5
申请日：2011-01-14
IPC分类号： A61K39/39 , A61K39/012
CPC分类号： A61K39/39 , A61K39/012 , A61K2039/552 , A61K2039/55566 , A61K2039/57
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公开(公告)号：EP2214701B1
公开(公告)日：2016-08-03
申请号：EP08843740.5
申请日：2008-11-03
申请人： The Board of Trustees of the University of Arkansas , The Texas A&M University System , University of Guelph
发明人： BOTTJE, Walter , HARGIS, Billy , BERGHMAN, Luc , KWON, Young, Min , COLE, Kimberly , COX, Mandy , LAYTON, Sherryll , EL-ASHRAM, Saeed , BARTA, John , TELLEZ, Guillermo
IPC分类号： A61K39/012 , A61K38/04
CPC分类号： A61K39/002 , A61K2039/523 , A61K2039/53 , C07K14/455 , C07K14/70575 , C07K2319/03 , Y02A50/412
摘要： Vaccines comprising TRAP polypeptides and Salmonella enteritidis vectors comprising TRAP polypeptides are provided. The vaccines may also include a CD 154 polypeptide capable of binding to CD40. Also provided are methods of enhancing an immune response against Apicomplexan parasites and methods of reducing morbidity associated with infection with Apicomplexan parasites.
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46.发明授权
公开(公告)号：EP2531215B1
公开(公告)日：2015-06-10
申请号：EP11705018.7
申请日：2011-01-14
IPC分类号： A61K39/39 , A61K39/012
CPC分类号： A61K39/39 , A61K2039/55566 , A61K2039/57
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47.发明公开METHODS AND COMPOSITIONS OF PROTEIN ANTIGENS FOR THE DIAGNOSIS AND TREATMENT OF TOXOPLASMA GONDII INFECTIONS AND TOXOPLASMOSIS 审中-公开方法和蛋白抗原组成的诊断和治疗弓形虫，弓形虫感染与弓形虫病
公开(公告)号：EP2654782A2
公开(公告)日：2013-10-30
申请号：EP11852177.2
申请日：2011-12-20
IPC分类号： A61K39/012 , A61K39/00
CPC分类号： C07K14/45 , A61K39/002 , G01N33/56905
摘要： Contemplated compositions, devices, and methods are drawn to various antigens from the pathogen
T. gondii and their use in various diagnostic tests, vaccines, and therapeutic agents. In particularly preferred aspects, the antigens are immunodominant and have quantified and known relative reactivities with respect to sera of a population infected with the pathogen, and/or have a known association with a disease parameter.-
48.发明授权ORAL ANTI-LEUCOCYTOZOONOSIS VACCINES BASED ON TRANSGENIC PLANTS 有权口服抗LEUCOCYTOZOONOSIS疫苗BASED对转基因植物
公开(公告)号：EP1767639B1
公开(公告)日：2012-02-29
申请号：EP05743390.6
申请日：2005-05-30
申请人： The Kitasato Institute (formerly known as School Juridical Person Kitasato Gakuen) , National Institute of Advanced Industrial Science and Technology
发明人： ITO, Akira Res. Center for Biologicals, The K.I. , GOTANDA, Toru Res. Center for Biologicals, The K.I , KOBAYASHI, Shigeki , KUME, Katsumi Res. Center for Biologicals, The K.I , MATSUMURA, Takeshi AIST Hokkaido
CPC分类号： C07K14/44 , A61K39/015 , A61K2039/542 , C12N15/8258
摘要： Potato leaf transformed by a vector which expresses an immunogenic protein gene R7 originating in the second generation schizont of Leucocytozoon caulleryi is administered as an oral vaccine to chickens. As a result, the antibody titer of the chickens can be successfully elevated.
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公开(公告)号：EP1068293B1
公开(公告)日：2012-01-25
申请号：EP99912985.1
申请日：1999-03-30
申请人： Eimeria Pty. Limited , The State of Queensland Through the Department of Primary Industries , RURAL INDUSTRIES RESEARCH AND DEVELOPMENT CORPORATION
IPC分类号： C12N1/10 , A61K39/012
CPC分类号： C12R1/01 , A61K39/00 , A61K39/012 , C07K14/455
摘要： Vaccines for the prevention and/or treatment of Eimeria infection including one or more strains of E. maxima ARI-73/97, E. acervulina ARI-77/97, E. tenella ARI-11/98, E. necatrix MCK01 and/or E. necatrix ARI-MEDNEC3+8 are described. Eimeria strains selected from E. maxima ARI-73/97, E. acervulina ARI-77/97, E. tenella ARI-11/98, E. necatrix MCK01 and/or E. necatrix ARI-MEDNEC3+8 are also described.
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50.发明公开
公开(公告)号：EP2335722A2
公开(公告)日：2011-06-22
申请号：EP10185573.2
申请日：2005-05-12
发明人： Stossel, Thomas , Lee, Po-Shun
IPC分类号： A61K39/085 , A61K39/04 , A61K39/09 , A61K39/012 , A61K39/018 , A61K39/015
CPC分类号： A61K38/1709 , Y02A50/463 , Y02A50/471 , Y02A50/475 , Y02A50/478 , Y02A50/48 , Y02A50/481
摘要： The invention relates to the use of plasma gelsolin to treat infections and to monitor the treatment of infections.
摘要翻译： 本发明涉及使用血浆凝溶胶蛋白治疗感染并监测感染的治疗。
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