公开(公告)号：EP2961429A1

公开(公告)日：2016-01-06

申请号：EP14716005.5

申请日：2014-02-28

申请人： MBN Nanomaterialia SpA

发明人： MATTEAZZI, Paolo ,  GHERLINZONI, Filippo ,  GOTTARDI, Michele

IPC分类号： A61K41/00 ,  A61K49/18 ,  B01J2/00 ,  A61N1/40 ,  A61N2/02 ,  A61P35/00

CPC分类号： A61K41/0052 ,  A61B5/055 ,  A61K9/5123 ,  A61K9/5192 ,  A61K49/1824 ,  A61K49/1863 ,  A61M5/007 ,  A61N1/403 ,  A61N1/406 ,  A61N2/004 ,  A61N2/02 ,  G01R33/281

摘要： The invention relates to a method for producing sub-micrometric particles, which comprises: mechanochemical treatment of homogeneous or heterogeneous magnetic materials until a mass which consists mostly of magnetic nanocrystal aggregates is obtained; selection of aggregates so that the nanocrystals have a Curie temperature within a predefined variation range; functionalization of the aggregates in order to obtain coating thereof with molecules of one or more of the following types of substances: substances for which the tumour cells have a particular metabolic avidity; substances having a biochemical affinity with the tumour cells; substances having an affinity with the acid microenvironment which surrounds the neoplastic cells. In addition to the method the following are claimed: the particles thus produced; their theranostic use which allows the in vivo execution, without interruption, of the diagnosis or monitoring step and the therapy step by means of magnetic hyperthermia of malignant neoplasms, including those localized in the so-called “sanctuary sites” such as the central nervous system and the testicle; an apparatus designed for this use.

摘要翻译： 本发明涉及一种用于制造亚微米粒子的方法，该方法包括：直到质量哪besteht大多的磁性纳米晶体聚集物获得均相或非均相磁性材料的机械化学处理; 聚集体的选择，以便做了纳米晶体具有预定的变化范围内的居里温度; 为了聚集体的官能化，以获得与一个或多个以下类型的物质的分子及其涂布：为其中肿瘤细胞具有代谢的特殊亲合力的物质; 具有与所述的肿瘤细胞的生物化学亲和力的物质; 具有围绕所述肿瘤细胞的微环境酸与亲和物质。 除了该方法要求保护以下内容：颗粒如此产生; 他们的治疗诊断学用途，其允许在体内执行，而不会中断，诊断或监测步骤和治疗步骤由恶性肿瘤，包括那些在所谓的“避难所站点”局部的磁热疗的手段：如对中枢神经系统 和睾丸; 设计用于这种用途设备。

公开(公告)号：EP2874735A1

公开(公告)日：2015-05-27

申请号：EP13765505.6

申请日：2013-07-17

申请人： Confetti, Cristian

发明人： Confetti, Cristian

IPC分类号： B01F3/18 ,  B01F5/18 ,  B01J2/00 ,  B28C5/04 ,  B01F15/02

CPC分类号： B01F3/18 ,  B01F5/18 ,  B01F15/0238 ,  B01F15/0253 ,  B01F2005/0034 ,  B28C5/04 ,  B28C5/464 ,  B28C5/48 ,  C04B33/025 ,  C04B33/14 ,  C04B35/62635 ,  C04B2235/5427 ,  C04B2235/5436

摘要： An apparatus for the preparation of colored materials in powder form for the manufacture of ceramic tiles, which comprises a mixer constituted by an upper cover (6) connected to the supply line (3) of the base material and by a mixing chamber (5); a vibrating frame (9) located between upper cover and mixing chamber; a perforated baffle fixed to the vibrating frame, the vibrating frame is connected with seal to the mixing chamber. The apparatus is provided with a system for the generation of an operating vacuum pressure in the upper cover and an injection system of the colorant at the base of the mixing chamber. The apparatus of the present invention produces a method for the preparation of colored materials in powder form for the manufacture of ceramic tiles, wherein the atomized and/or granulated ceramic material of uniform particle size, containing or not containing coloring substances, is fed uniformly into a chamber under vacuum pressure with respect to the mixing chamber connected to said chamber through a vibrated perforated baffle; coloring particles are injected at the base of a mixing chamber; the atomized and/or granulated ceramic material falls by gravity and is sprinkled inside the mixing chamber; and mixing in gaseous phase of the atomized and/or granulated ceramic material with the rising current of coloring particles.

公开(公告)号：EP2365024B1

公开(公告)日：2014-07-09

申请号：EP09830464.5

申请日：2009-12-04

申请人： Konishi Co., Ltd.

发明人： ORIGUCHI Toshiki ,  NAKAYAMA Yoshitaka

IPC分类号： C08J3/12 ,  A61K8/87 ,  A61Q13/00 ,  B01J2/00 ,  B01J2/04 ,  B01J20/26 ,  C08G18/10 ,  C08G18/48 ,  C09K3/00 ,  A61L9/01

CPC分类号： B05D1/12 ,  A61K8/11 ,  A61K8/25 ,  A61K8/87 ,  A61K2800/412 ,  A61Q19/00 ,  B01J20/103 ,  B01J20/262 ,  B01J20/28026 ,  B01J20/3212 ,  B01J20/3234 ,  B01J20/3295 ,  C08G18/0866 ,  C08G18/10 ,  C08G18/4854 ,  C08G18/755 ,  C08J3/12 ,  C08J2375/04 ,  C08G18/3228

公开(公告)号：EP2748124A1

公开(公告)日：2014-07-02

申请号：EP12756675.0

申请日：2012-08-24

申请人： Ekompany Agro B.V.

发明人： KAATHOVEN VAN, Hendrikus Gijsbertus Adrianus ,  XUAN BUI, Hoa

IPC分类号： C05G3/00 ,  B01J2/00 ,  B01J2/30 ,  C08G18/10 ,  C08G18/12 ,  C08G18/36 ,  C09D175/04

CPC分类号： C05G3/0029 ,  B01J2/006 ,  B01J2/12 ,  C05B7/00 ,  C05C1/00 ,  C05C9/00 ,  C05D1/00 ,  C08G18/10 ,  C09D175/04 ,  C08G18/36

摘要： The present invention relates to a process for producing polyurethane coated fertilizer granules comprising core granules in a rotating drum, wherein the drum comprises an inlet and an outlet and n application zones arranged along the longitudinal direction of the drum between the inlet and the outlet, n being an integer of at least 2 and wherein each of the application zones is followed by a curing zone. The curing zone after each application zone is arranged to allow an interval of 2-15 minutes, preferably 3-5 minutes, before the application in the successive application zone, wherein the polyol and the isocyanate are applied in the first application zone at a ratio of 0.5-4 wt%, preferably 1 -3 wt% of the core granules. The process comprises the steps of: A) continuously feeding the core granules to the inlet of the rotating drum, thereby providing a flow of the core granules in the direction from the inlet to the outlet, B1 ) applying a polyol and an isocyanate to the core granules in each of the n application zones, the ratio of hydroxyl groups in the polyol to NCO groups in the isocyanate at the end of each of the application zones being in the range from about 0.9 to about 1.3, B2) reacting the polyol and the isocyanate to form a tack-free polyurethane layer in each of the n curing zones and C) continuously collecting the polyurethane coated fertilizer granules from the outlet.

摘要翻译： 一种制造在旋转滚筒中具有核心颗粒的聚氨酯涂覆肥料颗粒的方法，其中所述滚筒具有入口和出口以及在所述入口和所述出口之间沿所述滚筒的纵向布置的n个施加区域，n为整数 至少2个，并且其中每个施用区域之后是固化区。 每个施用区域之后的固化区域被布置成允许间隔2-15分钟，优选3-5分钟，然后在连续施加区域中施用，其中多元醇和异氰酸酯以第一施用区域的比例 为核心颗粒的0.5-4重量％，优选1-3重量％。 该方法具有以下步骤：A）将核心颗粒连续供给到旋转鼓的入口，从而在从入口到出口的方向上提供芯颗粒的流动，B1）将多元醇和异氰酸酯施加到 在每个施加区域中的每一个中的核心颗粒，在每个施用区域的末端的异氰酸酯中的多元醇中的羟基与NCO基团的比例在约0.9至约1.3的范围内，B2）使多元醇和 异氰酸酯，以在n个固化区中的每一个中形成无粘性聚氨酯层，和C）从出口连续收集聚氨酯涂覆的肥料颗粒。

公开(公告)号：EP2387597A4

公开(公告)日：2014-05-14

申请号：EP10731935

申请日：2010-01-15

申请人： UNIV CORNELL

发明人： ARCHER LYNDEN A ,  OLENICK LAURA LYNNE ,  NUGENT JENNIFER LYN ,  CORONA ALEXANDRA MIRELLA ELENA

IPC分类号： C08L83/00 ,  B01J2/00 ,  C08K9/06

CPC分类号： B82Y30/00 ,  A61K9/5115 ,  A61K9/5192 ,  C08K3/08 ,  C08K3/22 ,  C08K9/06 ,  C10M171/06 ,  C10N2220/021 ,  C10N2220/082 ,  C10N2220/084 ,  C10N2250/12 ,  H01M10/05 ,  C08L71/02 ,  C08L83/04 ,  C08L101/00 ,  C08L33/10 ,  C08L69/00

公开(公告)号：EP2718245A1

公开(公告)日：2014-04-16

申请号：EP11770545.9

申请日：2011-08-18

申请人： UAB "Arvi" Ir Ko

发明人： SVIKLAS, Alfredas Martynas ,  KUCINSKAS, Vidmantas

IPC分类号： C05B7/00 ,  C05G3/00 ,  B01J2/00

CPC分类号： C05G3/0058 ,  B01J2/12 ,  C05B7/00 ,  C05B19/00 ,  C05C1/02 ,  C05C9/00 ,  C05D1/005 ,  C05D9/02

摘要： The method for production of granular compound fertilizers according to present invention comprises mixing the solid components within 1 to 10 min. with moist components, obtained from the tubular reactor, arranged in the bottom part of a mixer, wherein the alkaline components were neutralized with mineral acids. The temperature of a mixture is raised up to 140°C. Ammonia aqueous solutions, containing ammonium nitrate, urea, ammonium sulphate, calcium nitrate, magnesium nitrate or mixtures thereof, potassium hydroxide or potassium salts or mixtures thereof are used as the alkaline component, whereas nitric, phosphoric or sulphuric acids - as the acidic component. The amount of nitrogen in the granulated product is from 5 to 25%, by weight and sulphur - up to 15% by weight.

公开(公告)号：EP2363202B1

公开(公告)日：2013-07-10

申请号：EP09821936.3

申请日：2009-10-09

申请人： Freund Corporation

发明人： FUSEJIMA Yasutoyo ,  NAKAMURA Takuya ,  TERADA Takashi ,  ISOBE Shigemi

IPC分类号： B01J2/00 ,  A23P1/08 ,  A61J3/06 ,  B01J2/12 ,  B05D7/00 ,  A23L1/00 ,  A23G3/00 ,  A23G4/02

CPC分类号： A23G3/26 ,  A23G3/0063 ,  A23G3/0095 ,  A23G4/025 ,  A23P20/10 ,  A23P20/15 ,  A23P20/18 ,  A61J3/005 ,  B01J2/12 ,  B01J2/14 ,  B05B13/0257 ,  B05C3/08 ,  B05C15/00

公开(公告)号：EP2608876A2

公开(公告)日：2013-07-03

申请号：EP11817548.8

申请日：2011-08-23

申请人： Brinox, D.O.O.

发明人： TESLIC, Dusan

IPC分类号： B01J2/00 ,  B01J2/16 ,  B05B7/06

CPC分类号： B01J2/16 ,  B01J2/006 ,  B05B7/067

摘要： The subject of the invention is a processing device for granulating and coating of solid particles. The present invention refers to a technical field of particle coating, especially to a field of devices for spraying a coating liquid or suspension into a fluidised layer of particles. A processing device for granulating and coating of solid particles, where the device (1) has a processing medium distribution panel (4) arranged inside a wall (2), through which distribution panel (4) at least one nozzle (15) for atomising the liquid for coating or granulating is arranged, wherein under said distribution panel (4) there is a housing (3), which serves to supply a processing medium (5) through the distribution panel (4) into the area above the distribution panel (4), wherein the nozzle (15) for atomisation of the solution is designed in a way that part of the processing medium (5) is taken from the area below the distribution panel (4) and conducted to the area above the distribution panel (4) through a channel (12) that embraces the nozzle (15) concentrically and in the same flow direction with respect to a sprayed solution (7).

公开(公告)号：EP2590733A1

公开(公告)日：2013-05-15

申请号：EP11729636.8

申请日：2011-07-06

申请人： Neuhaus, Dietmar

发明人： Neuhaus, Dietmar

IPC分类号： B01J2/00

CPC分类号： B01J2/006

摘要： The invention relates to a method for moistening surfaces (101) of a solid body (100) with a gaseous moistening agent, in particular water, consisting of the following steps: a) exposing at least a part of the solid body (100) to a first atmosphere having a first relative humidity R1 of the moistening agent for a time period t1, in such a way that the moistening agent is adsorbed on the surface (109) of the solid body (100), b) exposing at least a part of the solid body to a second atmosphere having a second relative humidity of the moistening agent for a time period t2, in such a way that the moistening agent is partially desorbed from the surface of the solid body (100), c) repeating the steps a) and b) multiple times, and d) exposing at least a part of the solid body (100) to the first atmosphere for a time period t3.

公开(公告)号：EP2262851A4

公开(公告)日：2013-04-24

申请号：EP09720278

申请日：2009-03-13

申请人： UNIV TEXAS

发明人： TIMMONS RICHARD BRENDON ,  WAVHAL DATTATRAY ,  BHATTACHARYYA DHIMAN ,  MUKHERJEE NARAYAN

IPC分类号： C08J3/28 ,  B01J2/00 ,  C08J3/12 ,  C08J7/04 ,  C08J7/12 ,  C08J7/18 ,  C08K3/00 ,  C08K3/10 ,  C08K9/02 ,  C08K9/04

CPC分类号： C08F130/04 ,  B01J2/006 ,  C08G18/08 ,  C08G65/00 ,  C08J7/123 ,  C08J7/18 ,  C23C4/00 ,  C23C4/11 ,  C23C4/134 ,  C23C16/40 ,  Y10S977/788 ,  Y10S977/811

摘要： The present invention includes compositions and methods for synthesis of composite materials involving gas phase plasma polymerization to covalently plasma graft an organic molecule onto particles; covalently binding an organic monomer to the functionalized particles; and, polymerizing the organic monomers into hybrid polymer composite materials.

摘要翻译： 本发明包括用于合成涉及气相等离子体聚合的复合材料的组合物和方法，以将有机分子共价等离子体接枝到颗粒上; 将有机单体与官能化的颗粒共价结合; 并将有机单体聚合成杂化聚合物复合材料。