-
公开(公告)号：EP1325021A4
公开(公告)日：2005-05-04
申请号：EP01910338
申请日：2001-01-17
发明人： ROSEN CRAIG A , KOMATSOULIS GEORGE A , BAKER KEVIN P , BIRSE CHARLES E , SOPPET DANIEL R , OLSEN HENRIK S , MOORE PAUL A , WEI PING , EBNER REINHARD , DUAN D ROXANNE , SHI YANGGU , CHOI GIL H , FISCELLA MICHELE , NI JIAN
-
公开(公告)号：EP1044211A4
公开(公告)日：2005-03-23
申请号：EP99904021
申请日：1999-01-06
发明人： RUBEN STEVEN M , SOPPET DANIEL R , EBNER REINHARD , LAFLEUR DAVID W , NI JIAN , BREWER LAURIE A , OLSEN HENRIK S , DUAN ROXANNE D , ROSEN CRAIG A
-
公开(公告)号：EP1251863A4
公开(公告)日：2005-03-02
申请号：EP01910340
申请日：2001-01-17
发明人： ROSEN CRAIG A , KOMATSOULIS GEORGE A , BAKER KEVIN P , BIRSE CHARLES E , SOPPET DANIEL R , OLSEN HENRIK S , MOORE PAUL A , WEI PING , EBNER REINHARD , DUAN D ROXANNE , SHI YANGGU , CHOI GIL H , FISCELLA MICHELE , NI JIAN , RUBEN STEVEN M , BARASH STEVEN C
IPC分类号： A61K38/00 , A61K48/00 , C07K14/47 , C07K14/705 , A61K31/7088 , A61K31/713 , A61K38/16 , A61K38/43 , A61K39/395 , C12N9/00 , C12N15/12 , C12N15/52 , C12Q1/68 , G01N33/53 , G01N33/68
-
公开(公告)号：EP1088071A4
公开(公告)日：2005-03-02
申请号：EP99930252
申请日：1999-06-15
发明人： RUBEN STEVEN M , NI JIAN , ROSEN CRAIG A , WEI YING-FEI , YOUNG PAUL E , FLORENCE KIMBERLY A , SOPPET DANIEL R , BREWER LAURIE A , ENDRESS GREGORY A , CARTER KENNETH C , MUCENSKI MICHAEL , EBNER REINHARD , LAFLEUR DAVID W , OLSEN HENRIK S , SHI YANGGU , MOORE PAUL A , KOMATSOULIS GEORGE
IPC分类号： C12N15/09 , A61K38/00 , A61K39/395 , A61K48/00 , A61P43/00 , C07K7/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/12 , C12Q1/68 , G01N33/68
CPC分类号： G01N33/6893 , A61K38/00 , C07K14/47 , G01N2500/20
-
公开(公告)号：EP1317467A4
公开(公告)日：2004-12-22
申请号：EP01903079
申请日：2001-01-17
发明人： ROSEN CRAIG A , KOMATSOULIS GEORGE A , BAKER KEVIN P , BIRSE CHARLES E , SOPPET DANIEL R , OLSEN HENRIK S , MOORE PAUL A , WEI PING , EBNER REINHARD , DUAN D ROXANNE , SHI YANGGU , CHOI GIL H , FISCELLA MICHELE , NI JIAN
IPC分类号： C07K14/47 , C12N1/21 , C07H21/04 , C07H21/02 , C07K5/00 , C07K14/00 , C12N15/63 , C12N15/85 , C12N15/86 , C12Q1/68
CPC分类号： C07K14/47
-
66.发明公开POLYNUCLEOTIDES ENCODING HUMAN SERINE PROTEASES 审中-公开FüRHUMANE SERINPROTEASEN KODIERENDE POLYNUKLEOTIDE
公开(公告)号：EP1297117A4
公开(公告)日：2004-12-15
申请号：EP00942940
申请日：2000-06-20
发明人： RUBEN STEVEN M , NI JIAN , SHI YANGGU
IPC分类号： A61K38/00 , A61K48/00 , C12N9/64 , C12N15/57 , A61K31/713 , A61K38/48 , C12N15/70 , C12N15/79 , C12N15/85
CPC分类号： C12N9/6424 , A61K38/00 , A61K48/00
-
-
公开(公告)号：EP0896622A4
公开(公告)日：2004-11-03
申请号：EP97916062
申请日：1997-03-19
发明人： NI JIAN , GENTZ REINER L , SU JEFFREY Y , LI HAODONG
IPC分类号： C12N15/02 , A61K31/00 , A61K38/00 , A61K48/00 , A61P17/00 , A61P17/02 , A61P17/06 , A61P29/00 , A61P31/00 , A61P35/00 , A61P35/02 , A61P37/00 , A61P37/08 , A61P43/00 , C07K14/52 , C07K16/24 , C12N5/10 , C12N15/09 , C12N15/19 , C12P21/08 , C12Q1/00 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , A61K38/19 , G01N33/68
CPC分类号： C07K14/522 , A61K38/00 , A61K48/00 , C07K2319/00 , C12N2799/026
摘要： Human chemokine Alpha-2 polypeptides and DNA (RNA) encoding such chemotactic cytokines and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such chemotactic cytokines for the treatment of leukemia, tumors, chronic infections, autoimmune disease, fibrotic disorders, wound healing and psoriasis. Antagonists against such chemotactic cytokines and their use as a therapeutic to treat rheumatoid arthritis, autoimmune and chronic and acute inflammatory and infective diseases, allergic reactions, prostaglandin-independent fever and bone marrow failure are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to mutations in the nucleic acid sequences and altered concentrations of the polypeptides. Also disclosed are diagnostic assays for detecting mutations in the polynucleotides encoding the chemotactic cytokines and for detecting altered levels of the polypeptides in a host.
-
公开(公告)号：EP1259527A4
公开(公告)日：2004-10-27
申请号：EP00978417
申请日：2000-11-08
发明人： RUBEN STEVEN M , KOMATSOULIS GEORGE A , BIRSE CHARLES E , NI JIAN , MOORE PAUL A
IPC分类号： C12N15/09 , A61K31/7088 , A61K38/00 , A61K48/00 , A61P1/04 , A61P3/00 , A61P3/10 , A61P7/06 , A61P9/08 , A61P9/10 , A61P11/06 , A61P13/12 , A61P15/00 , A61P17/02 , A61P17/06 , A61P19/02 , A61P25/02 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/24 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/00 , A61P35/00 , A61P35/02 , A61P37/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12P21/02 , C12Q1/68
CPC分类号： C07K14/47
-
公开(公告)号：EP1322667A4
公开(公告)日：2004-08-18
申请号：EP01966151
申请日：2001-08-24
发明人： GENTZ REINER L , EBNER REINHARD , YU GUO-LIANG , RUBEN STEVEN M , NI JIAN , FENG PING
IPC分类号： A61K38/17 , C07K14/715 , C12Q1/68 , C07K14/705 , A61K38/00 , A61K39/00 , A61K39/395 , C07H21/04 , C12N5/00 , C12N15/63 , C12P21/02
CPC分类号： C07K14/7151 , A61K38/00 , C07K2319/30 , C12Q1/6883
-
-
-
-
-
-
-
-
-
搜索结果
109 条记录 (耗时 0.014 秒)
