公开(公告)号：EP0211206A1

公开(公告)日：1987-02-25

申请号：EP86108506.6

申请日：1986-06-21

申请人： PPG INDUSTRIES, INC.

发明人： Beaver, Richard Paul

IPC分类号： C03B37/14 ,  G01N30/56

CPC分类号： B01J20/28023 ,  B01J20/28014 ,  B01J20/281 ,  B01J2220/54 ,  C03B37/14 ,  G01N30/56 ,  G01N30/60 ,  G01N30/6043 ,  G01N30/6052 ,  Y10T29/49801 ,  Y10T29/49838 ,  Y10T29/49934 ,  Y10T29/53996 ,  G01N30/466

摘要： A packed tube of generally parallel aligned fibers is described, wherein the fibers are packed therein at densities of 60 to 100 percent of the theoretical packing density based on the fiber diameters used based on the selected fiber pitch pattern and preferably at 70 to 100 percent of the theoretical. Glass fibers which can be porous and/or hollow are preferred.

公开(公告)号：EP0042683B1

公开(公告)日：1985-12-18

申请号：EP81302486.6

申请日：1981-06-04

申请人： NATIONAL RESEARCH DEVELOPMENT CORPORATION

发明人： Thompson, John Michael ,  Sithamparanadarajah, Rajadurai ,  Stephen, William Irvine

IPC分类号： G01N1/22 ,  G01N30/00

CPC分类号： G01N1/2214 ,  G01N1/405 ,  G01N30/08 ,  G01N30/603 ,  G01N30/6052 ,  G01N30/6091 ,  G01N2001/2826 ,  G01N2030/0095

公开(公告)号：EP0023582A1

公开(公告)日：1981-02-11

申请号：EP80103834.0

申请日：1980-07-05

申请人： MERCK PATENT GmbH

发明人： Gunkel, Werner, Ing. grad. ,  Eisenbeiss, Friedhelm, Dr. Dipl.-Chem.

IPC分类号： B01D15/08 ,  G01N31/08

CPC分类号： B01D15/22 ,  G01N30/6052 ,  G01N30/36

摘要： Die Anmeldung betrifft eine Säule für die Hochdruckflüssigchromatographie, bestehend aus einer mit Sorptionsmittel zu füllenden Glassäule, die unter Einhaltung eines Zwischenraumes konzentrisch von einem Druckrohr umgeben ist, wobei die Glassäule an beiden Enden mit Dichtungen gegen den Zwischenraum abgedichtet ist und das Druckrohr einen Anschlussstutzen zur Zuführung eines Druckmittels besitzt, und wobei in dem Zwischenraum (4) eine flexible Membran (2) so angeordnet ist, dass sie die Glassäule (1) gegen das Druckmittel abdichtet.

摘要翻译： 本申请涉及用于高压液相色谱法由以下组成的成填充有吸附剂的玻璃柱的柱，其konrentrisch包围，同时保持通过压力管的间隙时，玻璃柱在密封既与针对中间空间和压力管密封件具有用于供给的连接件端部 压力介质，并且其中，在所述中间空间（4）的柔性膜（2）被布置成使得它密封关闭玻璃柱（1）对中的压力介质。

公开(公告)号：EP1926538B1

公开(公告)日：2018-10-31

申请号：EP06814680.2

申请日：2006-09-14

申请人： Waters Technologies Corporation

发明人： BUCHANAN, John ,  DELLAROVERE, Dennis

IPC分类号： B01D15/08 ,  B29D23/00 ,  B29C63/34 ,  F16L9/00 ,  F16L9/147 ,  B29C63/18 ,  B29C63/26

CPC分类号： G01N30/88 ,  B01L3/502753 ,  B01L3/565 ,  B01L2400/0415 ,  B01L2400/0487 ,  B29C63/18 ,  B29C63/34 ,  B29L2023/00 ,  G01N30/32 ,  G01N30/6052 ,  G01N30/7233 ,  G01N2030/324

摘要： A method for making conduits includes inserting an inner tube into an outer tube and melting a portion of the inner tube to form a bond with the outer tube. The inner tube includes a polymeric material and the outer tube includes a material having a greater yield strength than the polymeric material. A conduit includes one or more inner tubes at least one of which is melt-bonded to one or more outer tubes. An analytical instrument includes a separation column, a solvent reservoir and pump, a sample injector, a detector to observe an eluent of the separation column, and tubing to transport fluid between components of the instrument.

公开(公告)号：EP3006934B1

公开(公告)日：2017-02-01

申请号：EP15002788.6

申请日：2009-07-31

申请人： BioVentures, Inc.,

发明人： Dawson, Elliott, P.

IPC分类号： G01N30/60 ,  B01L3/00 ,  C12N15/10 ,  B01D15/22 ,  G01N30/38 ,  B01J20/281 ,  B01J20/26 ,  B01J20/283 ,  B01J20/285 ,  B01J20/291

CPC分类号： G01N30/6091 ,  B01D15/22 ,  B01J20/267 ,  B01J20/283 ,  B01J20/285 ,  B01J20/291 ,  B01J2220/58 ,  B01L3/5021 ,  B01L2300/042 ,  B01L2300/0681 ,  B01L2300/0832 ,  G01N30/6052 ,  G01N2030/381 ,  Y10T436/255

公开(公告)号：EP3006934A3

公开(公告)日：2016-06-08

申请号：EP15002788.6

申请日：2009-07-31

申请人： BioVentures, Inc.,

发明人： Dawson, Elliott, P.

IPC分类号： G01N30/60 ,  B01L3/00 ,  C12N15/10 ,  B01D15/22 ,  G01N30/38 ,  B01J20/281 ,  B01J20/26 ,  B01J20/283 ,  B01J20/285 ,  B01J20/291

CPC分类号： G01N30/6091 ,  B01D15/22 ,  B01J20/267 ,  B01J20/283 ,  B01J20/285 ,  B01J20/291 ,  B01J2220/58 ,  B01L3/5021 ,  B01L2300/042 ,  B01L2300/0681 ,  B01L2300/0832 ,  G01N30/6052 ,  G01N2030/381 ,  Y10T436/255

摘要： A spin column device, which contains a rigid porous filter that retains its shape during centrifugation and a volume control device, for isolating a desired substance, e.g., a biological molecule, from other substances in a mixture, and a kit containing the device and one or more reagents for use in an isolation or purification procedure.

公开(公告)号：EP2975398A1

公开(公告)日：2016-01-20

申请号：EP14765299.4

申请日：2014-03-11

申请人： Sekisui Medical Co., Ltd.

发明人： YOTANI, Takuya ,  OKA, Takayuki ,  MURAKI, Hideki

IPC分类号： G01N30/60 ,  G01N30/88

CPC分类号： G01N30/6026 ,  G01N30/16 ,  G01N30/6004 ,  G01N30/603 ,  G01N30/6047 ,  G01N30/6052 ,  G01N30/606 ,  G01N2030/8822

摘要： A cylindrical column body (101) holds a filler. A pair of end caps (105, 106) covers both ends of the column body (101) and has a flow hole for a carrier liquid (111, 112) arranged in the center thereof. An end surface on the side of a large diameter portion (113a, 114a) of a pair of columnar joint members (113, 114) contacts an end surface of the pair of end caps (105, 106) and also has a communication hole (115, 116) arranged in the center thereof. A sealing member (117, 118) is arranged on a contact surface between the end cap (105, 106) and the joint member (113, 114). A bottomed cylindrical case (121) accommodates the pair of end caps (105, 106) and a large diameter portion of the pair of joint members (113, 114) in an engaged state. A cover member (124) is detachably installed on a side of an opening of the case (121).

摘要翻译： 圆柱形柱体（101）保持填料。 一对端盖（105,106）覆盖柱体（101）的两端，并具有用于布置在其中心的载液（111,112）的流动孔。 一对柱状接头构件（113,114）的大径部（113a，114a）侧的端面与一对端盖（105,106）的端面接触，并且还具有连通孔 115,116）。 密封构件（117,118）布置在端盖（105,106）和接头构件（113,114）之间的接触表面上。 一个有底的圆筒形壳体（121）在接合状态下容纳一对端盖（105,106）和一对接头构件（113,114）的大直径部分。 盖构件（124）可拆卸地安装在壳体（121）的开口的一侧。

公开(公告)号：EP2748504B1

公开(公告)日：2015-12-09

申请号：EP12828696.0

申请日：2012-08-23

申请人： Waters Technologies Corporation

发明人： MICHIENZI, Joseph D.

IPC分类号： G01N30/60 ,  F16L19/02

CPC分类号： B05B5/16 ,  B01D15/10 ,  B01D15/1871 ,  B01D15/22 ,  G01N30/60 ,  G01N30/6004 ,  G01N30/6026 ,  G01N30/603 ,  G01N30/6039 ,  G01N30/6052 ,  G01N30/6095 ,  G01N30/7266 ,  Y10T29/49908

摘要： An apparatus for chemical separations includes a microfluidic substrate having an outlet aperture for outputting an eluent of a sample. An emitter assembly includes having a deformable end portion, an inlet near the deformable end portion to receive the sample eluent from the microfluidic substrate, and an electrically conductive outlet portion to emit a spray of the sample eluent. A force-applying unit applies a force to the emitter assembly that urges the deformable end portion into contact with the microfluidic substrate. The deformable end portion is more elastic than the microfluidic substrate so that the contact between the microfluidic substrate and the deformable end portion produces a substantially fluid-tight seal between the outlet aperture of the microfluidic substrate and the inlet of the emitter assembly.

公开(公告)号：EP2747861A4

公开(公告)日：2015-04-22

申请号：EP12828910

申请日：2012-08-23

申请人： WATERS TECHNOLOGIES CORP

发明人： MICHIENZI JOSEPH D ,  FADGEN KEITH ,  LEVEILLE SR WADE P ,  FISK RAYMOND P ,  MARZALKOWSKI JR FRANK JOHN

IPC分类号： G01N30/60 ,  B01D15/08 ,  F16L13/14

CPC分类号： B05B5/16 ,  B01D15/10 ,  B01D15/1871 ,  B01D15/22 ,  G01N30/60 ,  G01N30/6004 ,  G01N30/6026 ,  G01N30/603 ,  G01N30/6039 ,  G01N30/6052 ,  G01N30/6095 ,  G01N30/7266 ,  Y10T29/49908

摘要： An apparatus for chemical separations includes a microfluidic substrate having an outlet aperture for outputting an eluent of a sample. An emitter assembly includes having a deformable end portion, an inlet near the deformable end portion to receive the sample eluent from the microfluidic substrate, and an electrically conductive outlet portion to emit a spray of the sample eluent. A force-applying unit applies a force to the emitter assembly that urges the deformable end portion into contact with the microfluidic substrate. The deformable end portion is more elastic than the microfluidic substrate so that the contact between the microfluidic substrate and the deformable end portion produces a substantially fluid-tight seal between the outlet aperture of the microfluidic substrate and the inlet of the emitter assembly.

公开(公告)号：EP2748599A2

公开(公告)日：2014-07-02

申请号：EP12826759.8

申请日：2012-08-23

申请人： Waters Technologies Corporation

发明人： MICHIENZI, Joseph D.

IPC分类号： G01N30/60

CPC分类号： B05B5/16 ,  B01D15/10 ,  B01D15/1871 ,  B01D15/22 ,  G01N30/60 ,  G01N30/6004 ,  G01N30/6026 ,  G01N30/603 ,  G01N30/6039 ,  G01N30/6052 ,  G01N30/6095 ,  G01N30/7266 ,  Y10T29/49908

摘要： An apparatus for chemical separations includes a microfluidic substrate having an outlet aperture for outputting an eluent of a sample. An emitter assembly includes having a deformable end portion, an inlet near the deformable end portion to receive the sample eluent from the microfluidic substrate, and an electrically conductive outlet portion to emit a spray of the sample eluent. A force-applying unit applies a force to the emitter assembly that urges the deformable end portion into contact with the microfluidic substrate. The deformable end portion is more elastic than the microfluidic substrate so that the contact between the microfluidic substrate and the deformable end portion produces a substantially fluid-tight seal between the outlet aperture of the microfluidic substrate and the inlet of the emitter assembly.

摘要翻译： 描述了包括微流体衬底，耦合器和密封配件的层析色谱装置。 微流体基底可以包括一个或多个色谱柱，例如分析柱或捕获柱，以及与一个或多个色谱柱连通的入口。 耦合器扩散结合到微流体衬底的表面，使得耦合器中的开口与微流体衬底中的入口对齐。 密封配件包括设置在耦合器的开口中并与衬底表面接触的耐热密封剂。 该耦合器和密封配件能够实现与微流体基底的入口紧密流体密封连接，该微流体基底具有高拉伸和扭转强度，并且不需要使用粘合剂。