公开(公告)号：EP1883619A4

公开(公告)日：2010-05-12

申请号：EP06768635

申请日：2006-05-25

Applicant: CHOONGWAE PHARMA CORP

Inventor： HWANG TAE-SEOP ,  KIM HYUN-GYU

IPC: C07C213/02

CPC classification number: C07C227/04 ,  C07C229/64 ,  C07C251/24

公开(公告)号：EP1932826A4

公开(公告)日：2010-03-17

申请号：EP06746495

申请日：2006-05-17

Applicant: KISSEI PHARMACEUTICAL

Inventor： KASAI KIYOSHI ,  KUBOTA MINORU ,  SUZUKI RITSU ,  OZAWA TETSUJI ,  ISHIKAWA TAKEHIRO ,  KOBAYASHI MAKOTOI ,  SONEHARA JUNICHI ,  KOBAYASHI MASAHIRO

IPC: C07C67/313 ,  C07B53/00 ,  C07C65/24 ,  C07C69/94 ,  C07C213/02 ,  C07C217/22 ,  C07C255/54 ,  C07D303/22

CPC classification number: C07D303/22 ,  C07B53/00 ,  C07C67/08 ,  C07C67/31 ,  C07C69/94 ,  C07C213/06 ,  C07C253/30 ,  C07C255/54 ,  C07C217/22

公开(公告)号：EP2099738A1

公开(公告)日：2009-09-16

申请号：EP07765119.8

申请日：2007-07-07

Applicant: Clariant Finance (BVI) Limited

Inventor： BÜHRING, Dirk ,  GALLAS, Andreas ,  RAAB, Klaus ,  SCHERL, Franz Xaver ,  WACHSEN, Olaf

IPC: C07C213/02

CPC classification number: C07C213/02 ,  C07C217/08

Abstract: The invention provides a process for preparing polyetheramines of the formula (1) R2(NR1R3)n in which n is a number from 1 to 20, R2 represents an organic radical that contains between 2 and 600 oxalkylene groups, and R1 and R3 are alike or different and represent hydrogen or an organic radical having 1 to 400 carbon atoms, by combining a compound of the formula (2) with a compound of the formula (3) R2 (OH)n (3) in the presence of hydrogen with a metal-containing catalyst whose metal content, based on the dry, reduced catalyst excluding any support material that may be present, is composed either of at least 80% by mass of cobalt or, in the case of Raney catalysts, of at least 80% by mass of metals from the group consisting of cobalt and aluminium, the catalyst containing less than 5% by mass of copper.

公开(公告)号：EP1487573B1

公开(公告)日：2009-09-09

申请号：EP03743852.0

申请日：2003-03-07

Applicant: BASF SE

Inventor： GERLACH, Till ,  FUNKE, Frank ,  MELDER, Johann-Peter ,  ISELBORN, Stefan ,  RUDLOFF, Martin ,  HÜLLMANN, Michael

IPC: B01J23/00 ,  B01J23/755 ,  C07C213/02 ,  C07C209/16 ,  C07C209/26 ,  C07D295/02 ,  B01J37/03 ,  B01J37/06

CPC classification number: C07C213/02 ,  B01J23/70 ,  B01J23/755 ,  B01J37/03 ,  B01J37/06 ,  C07C209/16 ,  C07C209/26 ,  C07D295/023 ,  C07C211/03 ,  C07C217/08

公开(公告)号：EP2077989A1

公开(公告)日：2009-07-15

申请号：EP07820444.3

申请日：2007-09-21

Applicant: BASF SE

Inventor： SCHMIDTKE, Helmut ,  RUDLOFF, Martin

IPC: C07C213/02 ,  C07C217/08

CPC classification number: C07C213/02 ,  C07C217/08

Abstract: The invention relates to a method for producing electronic grade 2,2'-aminoethoxyethanol by reacting diethylene glycol with ammonia in a reactor in the presence of a catalyst, thereby obtaining a reaction mixture. A crude 2,2'-aminoethoxyethanol stream is separated from said mixture and is purified by distillation in a pure product column. The method according to the invention is characterized by drawing off from the pure product column a side stream that contains electronic grade 2,2'-aminoethoxyethanol. For this purpose, the diethylene glycol is guided across a filter having a separation degree of at least 99% for solid particles with a maximum particle size of ≤1.5 μm before it is supplied to the reactor.

公开(公告)号：EP1735266B1

公开(公告)日：2009-06-24

申请号：EP05763966.8

申请日：2005-03-09

Applicant: Emmellen Biotech Pharmaceuticals Limited

Inventor： GOLLAPUDY, Subrahmanyam ,  JOSHI, Sunil Vaman

IPC: C07C213/02 ,  C07C215/30

CPC classification number: C07C213/02 ,  C07B2200/07 ,  C07C215/30

Abstract: An efficient cost-effective process for preparation of l-erythro-2-amino-1-phenyl-1-propanol from l-1-phenyl-1-hydroxy-2-propanone, which comprises converting l-1-phenyl-1-hydroxy-2-propanone to l-1-phenyl-1-hydroxy-2-propanone oxime and reducing the oxime with a catalyst consisting of finely divided nickel and aluminium metals giving good diastereomeric purity and yield.

公开(公告)号：EP2029520A1

公开(公告)日：2009-03-04

申请号：EP07704345.3

申请日：2007-02-05

Applicant: BASF SE

Inventor： CAUWENBERGE, Gunther van ,  MELDER, Johann-Peter ,  HOFFER, Bram Willem ,  KRUG, Thomas ,  PICKENÄCKER, Karin ,  PAPE, Frank-Friedrich ,  SCHWAB, Ekkehard

IPC: C07C209/16 ,  C07C211/10 ,  C07C211/14 ,  C07C213/02 ,  C07C215/08

CPC classification number: C07C209/16 ,  C07C213/02 ,  C07C211/10 ,  C07C211/14 ,  C07C215/08

Abstract: The invention relates to a method for producing ethylene amines and ethanol amines by the hydrogenating amination of monoethylene glycol and ammonia in the presence of a catalyst. Said method is characterised in that it takes place in two stages: in the first stage, amination takes place on a hydroamination catalyst until a maximum monoethylene glycol yield of 40 % is obtained; and in the second stage a supported catalyst is used, which has an active mass containing ruthenium and cobalt, but no additional metal from group VIII and no metal from group IB, said catalyst having the form of catalyst moulded bodies. If said bodies are spherical or in the form of bars, their respective diameters are

公开(公告)号：EP1415979B1

公开(公告)日：2008-11-26

申请号：EP03254844.8

申请日：2003-08-01

Applicant: Chevron Oronite Company LLC

Inventor： Gray, James A.

IPC: C07C213/02 ,  C07C217/18

CPC classification number: C07C213/00 ,  C08F8/00 ,  C08F10/00 ,  C07C217/16

公开(公告)号：EP1490325B1

公开(公告)日：2008-11-05

申请号：EP02743616.1

申请日：2002-06-13

Applicant: Nicholas Piramal India Limited

Inventor： SAIGAL, Jagdish Chand, Sejal CHSL, Apt No 304 ,  GUPTA, Rajender Pershad, Row House no 5 ,  PANDIT, Vilas Vasant, A-3 Santoor, Pandurangwadi ,  DESAI, Anand Jagannath, B/8 Neelkanth Chaya ,  MEHTA, Navneet Vinodrai, 20 C J New Kapole Nivas ,  RANE, Shrikant Hambirrao, A/204, Ratnasagar CSHL

IPC: C07C213/02 ,  C07C215/42

CPC classification number: C07C209/48 ,  C07C213/02 ,  C07C213/08 ,  C07C2601/14 ,  C07C215/42 ,  C07C217/60 ,  C07C217/74

Abstract: A process for the preparation of hydroxy (cycloalkane/cyclokene) phenylethyl amine of the general formula (III) comprising alkylation of its precursor amine of general formula (II) which is in turn produced by an effective reduction process from its precursor cyanide having the general formula (I) using Raney Nickel (CORMIII) as catalyst where, either of R5 and R6 independently could be in meta or para position and R5, R6 are independently hydrogen, hydroxyl, alkyl, alkoxy, alkanoyloxy, cyano, nitro, alkylmercapto, amino, alkylamino, allkanamido, halo, trifluoromethyl, or taken together methylenedioxy, n is 0,1,2,3,4; R7 is hydrogen or alkyl of 1-7 carbon atom, R1 I H or alkyl of 1-3 carbon atom and R2 is alkyl of 1-3 carbon atom, the dotted line represents optional unsaturation. Compounds of formulae IV, V and VI are respectively derivatives of compounds I, II and III respectively.

公开(公告)号：EP1270545B1

公开(公告)日：2008-11-05

申请号：EP01917774.0

申请日：2001-04-02

Applicant: Takeda Pharmaceutical Company Limited

Inventor： YAMASHITA, M., 602, Sanveru hankyutsukaguchiekimae ,  KATO, Kaneyoshi ,  TAWADA, Hiroyuki

IPC: C07C217/60 ,  C07C213/02 ,  C07C235/34 ,  C07C231/12 ,  A61K31/137 ,  A61P25/28

CPC classification number: C07C235/34 ,  C07B2200/07 ,  C07C217/74 ,  C07C2602/10