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公开(公告)号：EP1562563B1
公开(公告)日：2010-03-03
申请号：EP03781632.9
申请日：2003-10-30
IPC分类号： A61K31/4402 , A61K31/60 , A61P11/00
CPC分类号： A61K31/635 , A61K31/35 , A61K31/353 , A61K31/37 , A61K31/428 , A61K31/47 , A61K31/60 , A61K31/606 , A61K2121/00
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公开(公告)号：EP1867322B1
公开(公告)日：2010-01-20
申请号：EP07380166.4
申请日：2007-06-11
IPC分类号： A61K9/06 , A61K31/17 , A61K31/573 , A61K31/60 , A61P17/06
CPC分类号： A61K9/0014 , A61K9/06 , A61K31/17 , A61K31/573 , A61K31/60 , A61K2300/00
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63.发明公开USE OF CIS-EPOXYEICOSATRIENOIC ACIDS AND INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE TO TREAT CONDITIONS MEDIATED BY PBR, CB2, AND NK2 RECEPTORS 审中-公开CIS环氧二十碳三的使用和可溶性环氧化物水解酶抑制剂造成BY PBR，CB2和NK OUT所产生疾病治疗
公开(公告)号：EP2124928A1
公开(公告)日：2009-12-02
申请号：EP07748853.4
申请日：2007-01-04
IPC分类号： A61K31/336 , A61K31/335 , A61K48/00 , A61K31/17 , A61K31/60 , A61K31/365 , A61K31/415 , A61K31/202 , A61K31/192
CPC分类号： A61K31/335 , A61K31/17 , A61K31/192 , A61K31/202 , A61K31/336 , A61K31/365 , A61K31/415 , A61K31/60 , A61K2300/00
摘要： The invention relates to the discovery that cis-epoxyeicosatraenoic acids (EETs) bind to and act as agonists of peripheral benzodiazepine receptor and the cannabinoid CB2 receptor. The invention provides methods of reducing symptoms of conditions whose activity is mediated by these receptors, including inhibiting anxiety, inhibiting the growth of cancer cells expressing peripheral benzodiazepine receptors, and reducing oxygen radical damage to cells, by contacting the cells with a cis-epoxyeicosantrienoic acid, an inhibitor of soluble epoxide hydrolase (sEH), or both. The invention further provides methods of inhibiting irritable bowel syndrome by administering to individuals with inhibiting irritable bowel syndrome a cis-epoxyeicosantrienoic acid, an inhibitor of soluble epoxide hydrolase (sEH), or both. In some embodiments, the method comprises administering to the individual a nucleic acid which inhibits expression of sEH.
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公开(公告)号：EP1613266A4
公开(公告)日：2009-05-06
申请号：EP04750308
申请日：2004-04-15
发明人： BABUL NAJIB
IPC分类号： A61K31/44 , A61K31/13 , A61K31/365 , A61K31/415 , A61K31/60
CPC分类号： A61K31/365 , A61K31/415 , A61K31/60 , A61K2300/00
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65.发明公开PHARMACEUTICAL COMPOSITION FOR THE ORAL ADMINISTRATION OF OMEGA POLYENOIC FATTY ACIDS 审中-公开药物组合物，OMEGA-多烯脂肪酸口服
公开(公告)号：EP2046305A2
公开(公告)日：2009-04-15
申请号：EP07765618.9
申请日：2007-06-26
申请人： Valpharma S.A.
IPC分类号： A61K9/48 , A61K31/202 , A61K31/366 , A61K31/60 , A61K45/06
CPC分类号： A61K9/4808 , A61K31/202 , A61K31/366 , A61K31/60 , A61K45/06 , A61K2300/00
摘要： A pharmaceutical composition for the oral administration of omega polyenoic fatty acids combined with one or more active principles incompatible therewith, is described; also described is a process for preparing said pharmaceutical composition.
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公开(公告)号：EP2046295A1
公开(公告)日：2009-04-15
申请号：EP07766448.0
申请日：2007-07-13
申请人： Unilever PLC
发明人： Elphick, Andrew James , Staniforth, John , Wang, Dong , Duncalf, David John , Rannard, Steven Paul , Long, James , Foster, Alison Jayne
IPC分类号： A61K9/16 , A61K31/167 , A61K31/192 , A61K31/60
摘要： A process for the production of a composition comprising a water-insoluble paracetamol or NSAID which comprises the steps of: a) providing a mixture comprising: i) a water-insoluble paracetamol or NSAID, ii) a water soluble carrier, and iii) a solvent for each of the paracetamol or NSAID and the carrier, and b) spray-drying the mixture to remove the or each solvent and obtain a substantially solvent-free nano-dispersion of the paracetamol or NSAID in the carrier.
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67.发明授权USE OF DIPYRIDAMOLE IN COMBINATION WITH ACETYLSALICYLIC ACID AND AN ANGIOTENSIN II ANTAGONIST FOR STROKE PREVENTION 有权复方制剂为防止触电有关检取潘生丁，阿司匹林和A ATII拮抗剂含
公开(公告)号：EP1603573B8
公开(公告)日：2009-04-01
申请号：EP04709596.3
申请日：2004-02-10
IPC分类号： A61K31/60 , A61K31/519 , A61K31/4184 , A61P9/00
CPC分类号： A61K31/519 , A61K31/4184 , A61K31/60 , A61K2300/00
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68.发明授权
公开(公告)号：EP1784166B1
公开(公告)日：2009-03-04
申请号：EP05792891.3
申请日：2005-08-31
发明人： KACZANOWSKI, Matt, John , WILLIAMS, Thomas, Daniel , TROMBLEY, Kurt, Franklin , REDMAN-FUREY, Nancy, Lee
CPC分类号： A61K31/195 , A61K9/1623 , A61K9/2018 , A61K31/60 , A61K31/7012 , A61K2300/00
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69.发明公开METHODS OF USING AND COMPOSITIONS COMPRISING THALIDOMIDE FOR TREATMENT, MODIFICATION AND MANAGEMENT OF FIBROMYALGIA 审中-公开使用方法和组合物沙利度胺治疗，修改和纤维肌痛供应
公开(公告)号：EP1680132A4
公开(公告)日：2009-01-14
申请号：EP04796214
申请日：2004-10-22
申请人： CELGENE CORP
发明人： ZELDIS JEROME B , FALECK HERBERT
IPC分类号： A61K31/70 , A61K20060101 , A61K31/19 , A61K31/415 , A61K31/44 , A61K31/445 , A61K31/454 , A61K31/485 , A61K31/497 , A61K31/506 , A61K31/55 , A61K31/551 , A61K31/553 , A61K31/56 , A61K31/60 , A61K31/7048 , A61P19/04
CPC分类号： A61K31/70 , A61K31/19 , A61K31/415 , A61K31/445 , A61K31/454 , A61K31/497 , A61K31/551 , A61K31/553 , A61K31/56 , A61K31/60 , A61K2300/00
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