利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

150 条记录 (耗时 0.035 秒)

    CARTRIDGE DEVICE WITH FLUIDIC JUNCTIONS FOR COAGULATION ASSAYS IN FLUID SAMPLES
    75.
    发明公开
    CARTRIDGE DEVICE WITH FLUIDIC JUNCTIONS FOR COAGULATION ASSAYS IN FLUID SAMPLES 审中-公开
    具有流体接头的流体装置用于流体样本中的混凝测定

    公开(公告)号：EP3198270A1

    公开(公告)日：2017-08-02

    申请号：EP15777815.0

    申请日：2015-09-25

    申请人： Abbott Point Of Care, Inc.

    发明人： DI TULLIO, Katrina Petronilla ,  TAYLOR, Jay Kendall ,  LEE-YOW, Niko Daniel ,  BALL, Sheila Diane ,  CAMPBELL, John Lewis Emerson

    IPC分类号： G01N33/49

    CPC分类号： G01N33/86 ,  B01L3/502715 ,  B01L3/50273 ,  B01L3/502738 ,  B01L2200/10 ,  B01L2300/0645 ,  B01L2300/0663 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2400/0406 ,  B01L2400/0487 ,  B01L2400/0672 ,  B01L2400/0688 ,  B01L2400/0694 ,  G01N27/4166 ,  G01N33/4905 ,  G01N2333/974

    摘要： The present invention relates to analytical testing devices comprising fluidic junctions and methods for assaying coagulation in a fluid sample received within the fluidic junctions. For example, the present invention may be directed to a sample analysis cartridge including an inlet chamber, a first conduit comprising a first junction configured to split a biological sample into at least first and second segments, a second conduit comprising a first reagent, a first sensor region, and a first fluidic lock valve, and a third conduit comprising a second reagent, a second sensor region, and a second fluidic lock valve. The sample analysis cartridge further includes a pump configured to push the first segment over the first sensor region to the first fluidic lock valve, and push the second segment over the second sensor region to the second fluidic lock valve.

    摘要翻译： 本发明涉及包含流体接头的分析测试装置和用于测定在流体接头内接收的流体样本中的凝结的方法。 例如，本发明可以涉及一种样本分析盒，该样本分析盒包括入口室，第一导管，第一导管和第二导管，所述第一导管包括被配置为将生物样本分成至少第一段和第二段的第一接头，包含第一试剂的第二导管， 传感器区域和第一流体锁定阀，以及包括第二试剂，第二传感器区域和第二流体锁定阀的第三导管。 样本分析盒还包括泵，该泵构造成将第一区段推过第一传感器区域到达第一流体锁定阀，并且将第二区段推过第二传感器区域到达第二流体锁定阀。

    METHOD AND APPARATUS FOR DETECTING AND COUNTING PLATELETS INDIVIDUALLY AND IN AGGREGATE CLUMPS
    80.
    发明公开
    METHOD AND APPARATUS FOR DETECTING AND COUNTING PLATELETS INDIVIDUALLY AND IN AGGREGATE CLUMPS 审中-公开
    方法和设备来检测和计数单血小板及血小板单位HEAP

    公开(公告)号：EP3026433A1

    公开(公告)日：2016-06-01

    申请号：EP16150962.5

    申请日：2009-03-20

    申请人： Abbott Point Of Care, Inc.

    发明人： WARDLAW, Stephen C. ,  LEVINE, Robert A. ,  LALPURIA, Niten V.

    IPC分类号： G01N33/50 ,  G01N33/49 ,  G01N15/02 ,  G01N15/14 ,  G01N33/80 ,  G01N33/58

    CPC分类号： G01N33/49 ,  G01N15/147 ,  G01N15/1475 ,  G01N2015/0076 ,  G01N2015/008 ,  G01N2015/0084 ,  G01N2015/0092 ,  G01N2015/1486

    摘要： A method for enumerating platelets within a blood sample is provided. The method includes the steps of: 1) depositing the sample into an analysis chamber adapted to quiescently hold the sample for analysis, the chamber defined by a first panel and a second panel, both of which panels are transparent; 2) admixing a colorant with the sample, which colorant is operative to cause the platelets to fluoresce upon exposure to one or more predetermined first wavelengths of light; 3) illuminating at least a portion of the sample containing the platelets at the first wavelengths; 4) imaging the sample, including producing image signals indicative of fluorescent emissions from the platelets, which fluorescent emissions have an intensity; 5) identifying the platelets by their fluorescent emissions, using the image signals; 6) determining an average fluorescent emission intensity value for the individual platelets identified within the sample; 7) identifying clumps of platelets within the sample using one or more of their fluorescent emissions, area, shape, and granularity; and 8) enumerating platelets within each platelet clump using the average fluorescent emission intensity value determined for the individual platelets within the sample.

    摘要翻译： 提供了一种用于血液样本中的血小板枚举方法。 该方法包括如下步骤：1）沉积该样品成分析室angepasst静止地保持用于分析的样品，由第一面板和第二面板，这两个面板是透明的限定的腔室; 2）将与样本，其中着色剂是可操作以使血小板在曝光时发出荧光以的光的一个或多个预定的第一波长的着色剂; 3）至少含照明在所述第一波长下的血小板的样本的至少一部分; 4）使样品成像，包括产生表示来自血小板，其中荧光发射强度必须荧光发射的图像信号; 5）确定由它们的荧光发射的血小板，使用图像信号; 6）对样品中所确定的个体的血小板的平均荧光发射强度值确定性开采; 7）确定使用一个或多个他们的荧光发射，面积，形状和粒度的样本内的血小板凝块; 和8）使用开采样品内的单个血小板的平均荧光发射强度值确定性列举每个血小板凝块内的血小板。