METHOD FOR INCREASING HYDROPHILICITY OF FLUORESCENT LABEL COMPOUNDS
    76.
    发明授权
    METHOD FOR INCREASING HYDROPHILICITY OF FLUORESCENT LABEL COMPOUNDS 有权
    步骤为亲荧光标记物

    公开(公告)号:EP1401962B1

    公开(公告)日:2006-09-13

    申请号:EP02755031.8

    申请日:2002-07-01

    IPC分类号: C09B62/44

    CPC分类号: C09B57/10

    摘要: The invention relates to fluorescent label compounds of formula or , wherein Z is a reactive group that can be used for covalent coupling of the fluorescent label compound to other molecules. Either the fluorophore is a dipyrrometheneboron difluoride dye and Y is a water-solubilizing moiety, or Y is -CH2CH2SO3 X where X is a cation. The invention also relates to the use of the compounds in bioanalytical assays and cytological or histological staining methods. The invention further relates to a method for increasing the hydrophilicity of fluorescent compounds.