-
81.发明公开STABILIZATION OF LIQUID SOLUTIONS OF RECOMBINANT PROTEIN FOR FROZEN STORAGE 审中-公开STABILISIERUNGFLÜSSIGERLÖSUNGENEINES REKOMBINANTEN PROTEINSFÜRGEFRORENE LAGERUNG
公开(公告)号：EP2150264A4
公开(公告)日：2014-09-24
申请号：EP08746549
申请日：2008-04-22
申请人： BAYER HEALTHCARE LLC
发明人： TSVETKOVA NELLY , JOSHI OMKAR , WU PAUL , WANG DEQIAN , DESPONDS ARNAUD
-
公开(公告)号：EP1935347B1
公开(公告)日：2014-08-13
申请号：EP07024260.7
申请日：2007-12-14
申请人： Bayer HealthCare LLC
发明人： Rebec, Mihailo V.
CPC分类号： A61B10/0035 , A61B17/20 , A61B17/205 , G01N2800/24
-
公开(公告)号：EP2054721B1
公开(公告)日：2013-12-04
申请号：EP07836648.1
申请日：2007-08-09
申请人： Bayer HealthCare LLC
发明人： SCHELL, Robert, D.
IPC分类号： G01N33/487
CPC分类号： G01N33/48771
-
84.发明公开DIMERIC MOLECULAR COMPLEXES WITH FREE CYSTEINE RESIDUES AND CONJUGATES THEREOF 审中-公开有免费的半胱氨酸残基和缀合物二聚体分子复合
公开(公告)号：EP2648751A2
公开(公告)日：2013-10-16
申请号：EP11846369.4
申请日：2011-12-07
申请人： Bayer HealthCare LLC
发明人： LIGHT, David , SZYMANSKI, Paul , SETO, Marian , CORNELIUS, Aline
IPC分类号： A61K39/395 , A61K47/48
CPC分类号： C07K16/00 , A61K51/088 , C07K16/18 , C07K2317/528 , C07K2317/53 , C07K2317/55 , C07K2317/60 , C07K2317/64 , C07K2317/94 , C07K2319/00 , C07K2319/01
摘要： The invention relates generally to dimeric molecular complexes comprising two fusion proteins. Each fusion protein comprises a biological effector moiety, a polypeptide spacer sequence, and an IgE CH4 dimerization domain. The dimeric molecular complexes may be conjugated, at a defined site, to other molecules including drug moieties, cytotoxic agents, labels (such as detectable labels), or biocompatible polymers.
-
85.发明授权Aryl urea compounds in combination with other cytostatic or cytotoxic agents for treating human cancers 有权Arylharnstoffverbindungen在与其他细胞生长抑制剂或细胞毒性药物联合用于人类治疗癌症
公开(公告)号：EP1769795B1
公开(公告)日：2013-07-24
申请号：EP06023696.5
申请日：2002-12-03
申请人： Bayer HealthCare LLC
发明人： Carter, Christopher A. , Gibson, Neil , Hibner, Barbara , Humphrey, Rachel W. , Trail, Pamela , Vincent, Patrick W. , Zhai, Yifan
IPC分类号： A61K31/44 , A61K31/535 , A61K31/65 , A61K31/435 , A61K31/505 , A61K31/47
CPC分类号： C07D213/81 , A61K31/337 , A61K31/435 , A61K31/44 , A61K31/4412 , A61K31/47 , A61K31/4745 , A61K31/505 , A61K31/513 , A61K31/535 , A61K31/65 , A61K31/704 , A61K31/7072 , A61K45/06 , A61K2300/00
摘要： This invention relates to aryl urea compounds in combination with cytotoxic or cytostatic agents for use in treating raf kinase mediated diseases such as cancer
-
公开(公告)号：EP2461821A4
公开(公告)日：2013-07-03
申请号：EP10805185
申请日：2010-08-02
申请人： BAYER HEALTHCARE LLC
发明人： BROOKS ALAN , PATEL CHANDRA , JIANG XIAOQIAO , GRITZAN UWE , APELER HEINER , WANG JUN
IPC分类号： A61K38/36
CPC分类号： C12N9/644 , A61K38/00 , C12Y304/21022
-
公开(公告)号：EP1963372B1
公开(公告)日：2013-07-03
申请号：EP06847583.9
申请日：2006-12-12
申请人： Bayer Healthcare LLC
发明人： TAMBURINI, Paul , RANGES, Gerald , ADNANE, Lila , MCCABE, Timothy , TRAIL, Pamela , HA, Sha
IPC分类号： C07K16/28 , A61K39/395 , C07K16/30 , C07K16/40 , A61K47/48 , C12N15/13 , A61K31/7068
CPC分类号： C07K16/40 , A61K39/395 , A61K47/6803 , A61K47/6817 , A61K47/6851 , A61K47/6871 , A61K2039/505 , C07K16/30 , C07K2317/21 , C07K2317/55 , C07K2317/565 , C07K2317/732 , C07K2317/77 , C07K2317/92 , A61K2300/00
-
公开(公告)号：EP2049062B1
公开(公告)日：2013-06-26
申请号：EP07762316.3
申请日：2007-05-24
发明人： TUCKWELL, Jonathan David , DYER, Robert , KIVLIN, Robert Owen , PALMER-FELGATE, John Paul , AVERY, Matthew Burgess , SKINNER, Kevin, George , KADAMUS, Chris , WOOD, Lee , SCHWAN, Peter , ARLETT, Ben
IPC分类号： A61J1/20
CPC分类号： A61J1/2096 , A61J1/201 , A61J1/2051 , A61J1/2055 , A61J1/2075 , A61J1/2082 , A61J1/2086 , Y10T29/49826
-
89.发明公开DRUG COMBINATIONS WITH FLUORO-SUBSTITUTED OMEGA-CARBOXYARYL DIPHENYL UREA FOR THE TREATMENT AND PREVENTION OF DISEASES AND CONDITIONS 审中-公开与经氟OMEGA羧芳二苯基用于治疗和预防疾病和病症的有效组合
公开(公告)号：EP2595628A1
公开(公告)日：2013-05-29
申请号：EP11740767.6
申请日：2011-07-19
申请人： Bayer HealthCare LLC
发明人： CHRISTENSEN, Olaf , KUSS,Iris
IPC分类号： A61K31/44 , A61K31/505 , A61K31/519 , A61P35/00
CPC分类号： A61K31/44 , A61K31/505 , A61K31/519 , A61K33/24 , A61K45/06 , A61K2300/00
摘要： The present invention relates to drug combinations and pharmaceutical compositions for treating hyperproliferative disorders such as cancer including non-small cell lung carcinoma, said drug combination comprising (1) a fluoro-substituted-diaryl urea of Formula (I), (2) at least one antifolate and optionally (3) at least one platinum complex antineoplastic nucleic acid binding agent, where any of these components can be present in the form of a pharmaceutically acceptable salt or other derivative thereof.
-
90.发明公开New Pharmaceutical Compositions for the Treatment of Hyper-Proliferative Disorders 审中-公开Neue pharmazeutische Zusammensetzungenfürdie Behandlung von hyperproliferativenStörungen
公开(公告)号：EP2589384A1
公开(公告)日：2013-05-08
申请号：EP13151040.6
申请日：2005-08-29
申请人： Bayer Healthcare LLC
发明人： Skrabs, Susanne , Dumas, Jacques , Ehrlich, Paul
CPC分类号： A61K31/44 , A61K9/0053 , A61K9/146 , A61K9/1623 , A61K9/1635 , A61K9/1652 , A61K9/2027 , A61K9/2054 , A61K9/48 , A61K31/4415
摘要： This invention relates to novel pharmaceutical compositions comprising a solid dispersion of the compound of Formula I below, to processes for preparing these novel pharmaceutical compositions and to their use for treating hyper-proliferative disorders, such as cancer, either as a sole agent or in combination with other therapies.
Formula I is as follows:摘要翻译： 本发明涉及包含以下式I化合物的固体分散体的新型药物组合物，用于制备这些新型药物组合物的方法及其用于治疗高增殖性疾病如癌症的用途，作为唯一的药剂或组合 与其他疗法。 公式一如下：
-
-
-
-
-
-
-
-
-
搜索结果
1021 条记录 (耗时 0.038 秒)
