Bicarbonate-Based solutions for dialysis therapies
    82.
    发明公开
    Bicarbonate-Based solutions for dialysis therapies 审中-公开
    LÖSUNGENENTHALTEND BIKARBONAT FUR DIALYSETHERAPIE

    公开(公告)号:EP2322237A1

    公开(公告)日:2011-05-18

    申请号:EP10075494.4

    申请日:2002-11-04

    IPC分类号: A61M1/28 A61K33/14 A61P13/12

    摘要: Bicarbonate containing solutions for use during medical treatment are provided. The bicarbonate containing solution of the present invention includes at least two separate components including a bicarbonate concentrate and an electrolyte concentrate which can be readily and sterilely mixed to form a ready-to-use formulation for patient administration, particularly as applied to the treatment of acute renal failure associated with critically ill patients in an intensive care setting.

    摘要翻译: 提供了在医疗中使用的含碳酸氢盐溶液。 本发明的含碳酸氢盐溶液包括至少两种分离的组分,包括碳酸氢盐浓缩物和电解质浓缩物,其可以容易地和无菌地混合以形成用于患者给药的即用型制剂,特别是用于治疗急性 重症监护病房与危重病人相关的肾衰竭。

    Method for releasing and labelling O-glycans
    86.
    发明公开
    Method for releasing and labelling O-glycans 审中-公开
    Verfahren zur Gewinnung und Markierung von O-Glykanen

    公开(公告)号:EP2305692A1

    公开(公告)日:2011-04-06

    申请号:EP09252302.6

    申请日:2009-09-29

    摘要: The application describes a one-pot process for releasing and labelling 0-glycans from glycoproteins, thereby facilitating analysis via LC-ESl-MS-MS. The process comprises contacting the glycoprotein with an amine, eg. methylamine, dimethylamine, or ammonia, NH 3 in the presence of a labelling agent, especially 1-phenyl-3-methyl-5-pyrazolone (PMP; CAS Reg. No. 89-25-8), 1-naphthyl-3-methyl-5-pyrazolone (NM P) or 1-(4-methoxy)phenyl-3-methyl-5-pyrazolone (PMPMP, CAS Reg. No. 60798-06-3).

    摘要翻译: 该申请描述了从糖蛋白释放和标记O-聚糖的一锅法,从而便于通过LC-ES1-MS-MS进行分析。 该方法包括使糖蛋白与胺接触,例如。 甲基胺,二甲胺或氨,NH 3在标记试剂,特别是1-苯基-3-甲基-5-吡唑啉酮(PMP; CAS Reg.No.89-25-8)存在下,1-萘基-3- 甲基-5-吡唑啉酮(NM P)或1-(4-甲氧基)苯基-3-甲基-5-吡唑啉酮(PMPMP,CAS Reg.No.60798-06-3)。

    System for detecting patient access disconnection
    88.
    发明公开
    System for detecting patient access disconnection 有权
    系统zum Erfassen eines unterbrochenen Patientenzugangs

    公开(公告)号:EP2255840A2

    公开(公告)日:2010-12-01

    申请号:EP10075427.4

    申请日:2003-04-02

    IPC分类号: A61M1/36 A61B5/00

    摘要: Apparatuses, devices, systems and methods for detecting access disconnection during medical therapy are provided. The present invention includes an electric circuit coupled to, for example, a blood circuit used during dialysis therapy. The electric circuit can be adapted to inject an electrical signal into the blood circuit such that changes in an electrical valve in response to access disconnection, such as needle drop-out or catheter drop-out, can be effectively detected.

    摘要翻译: 提供了用于在药物治疗期间检测进入断开的装置,装置,系统和方法。 本发明包括耦合到例如在透析治疗期间使用的血液回路的电路。 电路可以适于将电信号注入到血液回路中,使得能够有效地检测响应于诸如针脱出或导管脱出的入口断开的电气阀的变化。