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公开(公告)号：EP3259597B1
公开(公告)日：2022-04-06
申请号：EP16711051.9
申请日：2016-02-19
发明人： WHITE, Mark , KUMAR, Sandeep , CHAN, Christopher , LIANG, Spencer , STAPLETON, Lance , DRAKE, Andrew W. , GOZLAN, Yosi , VAKNIN, Iian , SAMEAH-GREENWALD, Shirley , DASSA, Liat , TIRAN, Zohar , COJOCARU, Gad, S. , LEVY, Ofer , MACHLENKIN, Arthur , TOPORIK, Amir , KLIGER, Yossef , NEMZER, Sergey , NOVIK, Amit , BENITA, Yair
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公开(公告)号：EP3185885B1
公开(公告)日：2020-08-19
申请号：EP15836989.2
申请日：2015-08-26
申请人： Compugen Ltd.
IPC分类号： C07K16/28 , G01N33/564 , A61K38/04 , A61K38/00 , A61K38/17 , A61K39/00 , C07K14/705 , A61K39/39 , G01N33/68
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公开(公告)号：EP3295951B1
公开(公告)日：2020-04-22
申请号：EP17192325.3
申请日：2016-02-19
申请人： Compugen Ltd.
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公开(公告)号：EP3347379A1
公开(公告)日：2018-07-18
申请号：EP17797429.2
申请日：2017-08-17
申请人： Compugen Ltd.
发明人： WHITE, Mark , KUMAR, Sandeep , CHAN, Christopher , LIANG, Spencer , STAPLETON, Lance , DRAKE, Andrew, W. , GOZLAN, Yosi , VAKNIN, Ilan , SAMEAH-GREENWALD, Shirley , DASSA, Liat , TIRAN, Zohar , COJOCARU, Gad., S. , KOTTURI, Maya , CHENG, Hsin-Yuan , HANSEN, Kyle , GILADI, David, Nisim , SAFYON, Einav , OPHIR, Eran , PRESTA, Leonard , THEOLIS, Richard , DESAI, Radhika , WALL, Patrick
摘要： Anti-PVRIG and anti-TIGIT antibodies are provided.
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5.发明公开
公开(公告)号：EP3202415A2
公开(公告)日：2017-08-09
申请号：EP17161149.4
申请日：2011-06-30
申请人： Compugen Ltd.
CPC分类号： C07K14/4713 , A61K38/1709 , Y02A50/40 , Y02A50/401
摘要： This invention relates to a protein C1ORF32 and its variants and fragments and fusion proteins thereof, and methods of use therof for immunotherapy, and drug development, including but not limited to as immune modulators and for immune therapy, including for autoimmune disorders.
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公开(公告)号：EP2240601B1
公开(公告)日：2016-10-12
申请号：EP08867219.1
申请日：2008-12-01
申请人： Compugen Ltd.
发明人： KINAR, Yaron , BEIMAN, Merav , MONTIA, Eve , WALLACH, Shira , PERGAM, Tania , NOVIK, Amit , SAMEAH-GREENWALD, Shirley , COJOCARU, Gad S. , COHEN-DAYAG, Anat , FURMAN, Yael
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/106 , C12Q2600/136 , C12Q2600/142 , C12Q2600/156 , C12Q2600/158 , G01N33/6893 , G01N2800/347 , G01N2800/60
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7.发明公开
公开(公告)号：EP3043819A1
公开(公告)日：2016-07-20
申请号：EP14844096.9
申请日：2014-09-11
申请人： Compugen Ltd.
发明人： LEVINE, Zurit , ROTMAN, Galit , DASSA, Liat , LEVY, Ofer , COJOCARU, Gad S. , TOPORIK, Amir , KLIGER, Yossef , POW, Andrew , LIANG, Spencer
IPC分类号： A61K39/395 , C07K16/18 , G01N33/574 , C07K16/30 , G01N33/564 , G01N33/569
CPC分类号： C07K16/28 , A61K31/664 , A61K38/00 , A61K39/0011 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , A61K2039/5154 , C07K14/705 , C07K16/2803 , C07K16/2818 , C07K16/30 , C07K2317/21 , C07K2317/33 , C07K2317/51 , C07K2317/515 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C07K2319/30 , G01N33/564 , G01N33/57492 , G01N2800/24 , G01N2800/26 , G01N2800/50 , G01N2800/52 , G01N2800/54 , G01N2800/56 , Y02A50/41 , Y02A50/412 , Y02A50/416 , Y02A50/421 , Y02A50/466 , Y02A50/491 , Y02A50/492 , Y02A50/55 , Y02A50/58 , A61K31/675 , A61K2039/5152 , A61K38/1774
摘要： The present invention relates to VSTM5-specific antibodies, antibody fragments, and VSTM5 polypeptides, conjugates and compositions comprising same, for modulating (antagonizing or agonizing) one or more of the effects of VSTM5 expression on immunity. More specifically, the present invention relates to VSTM5-specific antibodies, antibody fragments, and VSTM5 polypeptides, conjugates and compositions comprising same for treating and aiding in the diagnosis of cancer, infectious diseases and immune related diseases, e.g., those associated with aberrant (higher or lower than normal) VSTM5 expression by diseased and/or immune cells and/or aberrant (increased or reduced) VSTM5-mediated effects on immunity.
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公开(公告)号：EP2816351A3
公开(公告)日：2015-03-25
申请号：EP13005799.5
申请日：2005-01-27
申请人： Compugen Ltd.
发明人： Diber, Alex , Pollock, Sarah , Levine, Zurit , Nemzer, Sergey , Rosenberg, Avi , Zekharia, Tomer , Novik, Amit , Cojocaru, Gad S. , Haviv, Ami , Shaked, Zipi , Farkash, Ariel , Privman, Eyal , Dahary, Dvir , Beck, Nili
CPC分类号： C07K14/705 , G06F19/20 , G06F19/22 , G06F19/28
摘要： Polypeptide sequences and polynucleotide sequences are provided. Also provided are annotative information concerning such sequences and uses for these sequences.
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公开(公告)号：EP2744830A1
公开(公告)日：2014-06-25
申请号：EP13806165.0
申请日：2013-06-19
申请人： Compugen Ltd.
发明人： COJOCARU, Gady S. , DASSA, Liat , ROTMAN, Galit , LEVY, Ofer , POW, Andrew , SAMEACH-GREENWALD, Shirley , LEVINE, Zurit
IPC分类号： C07K16/28 , A61K39/395 , A61P35/00 , A61P37/04
CPC分类号： A61K31/675 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/507 , C07K14/70503 , C07K16/28 , C07K16/2818 , C07K16/2878 , C07K16/30 , C07K2317/21 , C07K2317/34 , C07K2317/55 , C07K2317/734 , C07K2319/30 , C12N15/1138 , C12N2310/14 , G01N33/57492 , G01N2800/24 , G01N2800/26 , Y02A50/412 , Y02A50/423 , A61K2300/00
摘要： This invention relates to antibodies and antigen binding fragments and conjugates containing same, and/or alternative scaffolds, specific for LSR molecules, which are suitable drugs for immunotherapy and treatment of specific cancer.
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公开(公告)号：EP2167534B1
公开(公告)日：2012-07-04
申请号：EP08826161.5
申请日：2008-07-11
申请人： Compugen Ltd.
发明人： SHEMESH, Ronen , LEVINE, Zurit , TOPORIK, Amir , HERMESH, Chen , KLIGER, Yossef , GOFER, Eyal , WOOL, Assaf , DAHARY, Dvir , COHEN, Yossi
CPC分类号： C07K14/472 , A61K38/00 , C07K7/06 , C07K14/47 , C07K14/78 , C07K16/18 , C07K2317/34
摘要： Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating disorders associated with G-protein coupled receptor activation.
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