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    SYSTEMS AND METHODS FOR ANALYSIS AND TREATMENT OF A BODY LUMEN
    1.
    发明公开
    SYSTEMS AND METHODS FOR ANALYSIS AND TREATMENT OF A BODY LUMEN 审中-公开
    系统和方法进行分析和治疗体腔

    公开(公告)号：EP2432394A2

    公开(公告)日：2012-03-28

    申请号：EP10778436.5

    申请日：2010-05-20

    申请人： Cornova, Inc.

    发明人： RYAN, S., Eric ,  TANG, Jing ,  GAMBALE, Richard

    IPC分类号： A61B5/1455 ,  A61B5/1459

    CPC分类号： A61B5/0086 ,  A61B5/0066 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/02007 ,  A61B5/6852 ,  A61B5/6853 ,  A61B2017/22001 ,  A61N5/0601

    摘要： A system for analyzing a body lumen including a flexible conduit that is elongated along a longitudinal axis, the flexible conduit having a proximal end and a distal end; at least one delivery waveguide and at least one collection waveguide extending along the flexible conduit, a transmission output of the at least one delivery waveguide and a transmission input of the at least one collection waveguide located along a distal portion of the conduit; a spectrometer connected to the at least one delivery waveguide and the at least one collection waveguide, the spectrometer configured to perform diffuse reflectance spectroscopy, wherein the spectrometer emits at least one primary radiation signal of a wavelength having an absorption coefficient of between about 8 cm-1 and about 10 cm-1 when transmitted through a highly aqueous media; a controller system configured to calculate at least one of an extent, area, and volume of highly aqueous media based on the amount of absorption of the at least one primary radiation signal measured through the highly aqueous media by the spectrometer.

    SYSTEMS AND METHODS FOR ANALYSIS AND TREATMENT OF A BODY LUMEN
    7.
    发明公开
    SYSTEMS AND METHODS FOR ANALYSIS AND TREATMENT OF A BODY LUMEN 审中-公开
    用于分析和治疗体液的系统和方法

    公开(公告)号：EP2432542A2

    公开(公告)日：2012-03-28

    申请号：EP10778432.4

    申请日：2010-05-20

    申请人： Cornova, Inc.

    发明人： RYAN, S., Eric ,  TANG, Jing ,  GAMBALE, Richard

    IPC分类号： A61M25/10 ,  A61M25/092 ,  A61M25/16

    CPC分类号： A61B5/0086 ,  A61B5/0066 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/02007 ,  A61B5/6852 ,  A61B5/6853 ,  A61B2017/22001 ,  A61N5/0601

    摘要： A catheter for placement within a body lumen, the catheter including a flexible conduit that is elongated along a longitudinal axis, the flexible conduit having a proximal end and a distal end, at least one delivery waveguide and at least one collection waveguide extending along the flexible conduit, a lumen-expanding inflatable balloon disposed about a portion of the conduit, a transmission output of the at least one delivery waveguide and a transmission input of the at least one collection waveguide located within the balloon; and, at least one elongate arm connected to the conduit and positioned within the balloon, the at least one elongate arm radially translatable with respect to the conduit, and wherein at least one of the transmission output and transmission input is coupled to the elongate arm.

    摘要翻译： 一种用于放置在体腔内的导管，所述导管包括沿着纵向轴线伸长的柔性导管，所述柔性导管具有近端和远端，至少一个输送波导和至少一个收集波导，所述收集波导沿着柔性 围绕所述导管的一部分布置的管腔膨胀可膨胀气囊，所述至少一个传送波导的传输输出和位于所述气囊内的所述至少一个收集波导的传输输入; 以及至少一个细长臂，所述至少一个细长臂连接到所述导管并且定位在所述气囊内，所述至少一个细长臂相对于所述导管可径向平移，并且其中所述变速器输出和变速器输入中的至少一个联接到所述细长臂。

    IMPLANTABLE DEVICES AND METHODS OF FORMING THE SAME
    9.
    发明公开
    IMPLANTABLE DEVICES AND METHODS OF FORMING THE SAME 审中-公开
    植入产品和方法教育

    公开(公告)号：EP2077797A2

    公开(公告)日：2009-07-15

    申请号：EP07814498.7

    申请日：2007-08-28

    申请人： Cornova, Inc.

    发明人： RYAN, S., Eric ,  SAHAGIAN, Richard

    IPC分类号： A61F2/06

    CPC分类号： C23C14/025 ,  A61F2/82 ,  A61L31/088 ,  A61L31/18 ,  C23C14/027 ,  C23C14/165 ,  C23C14/505

    摘要： Textured coatings for implantable medical devices can be provided in metallic or polymer surface layers having surface texture factors down to nanometer and sub-nanometer levels. Implantable devices having such textured surfaces and methods of coating such devices comprises providing a substrate surface of an implantable device and forming a coating layer of the substrate surface by directing a mixture of atoms of a first type of material and a second type of material toward the substrate surface while simultaneously and collinearly bombarding the substrate surface with ions, wherein the first type of material is substantially resistant to a removal process and the second type of material is substantially susceptible to a removal process.

    SYSTEMS AND METHODS FOR ANALYSIS AND TREATMENT OF A BODY LUMEN
    10.
    发明公开
    SYSTEMS AND METHODS FOR ANALYSIS AND TREATMENT OF A BODY LUMEN 审中-公开
    用于分析和治疗体液的系统和方法

    公开(公告)号：EP2618717A2

    公开(公告)日：2013-07-31

    申请号：EP11827466.1

    申请日：2011-09-21

    申请人： Cornova, Inc.

    发明人： RYAN, S. Eric ,  TANG, Jing ,  GAMBALE, Richard

    IPC分类号： A61B1/00 ,  A61B5/027 ,  G01J3/00

    CPC分类号： A61B5/0086 ,  A61B5/0062 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/02007 ,  A61B5/1076 ,  A61B5/4836 ,  A61B5/6853 ,  A61M25/104 ,  G01J3/0218 ,  G01J3/0264 ,  G01J3/42

    摘要： A system is provided for probing a body lumen that includes a flexible conduit that is elongated along a longitudinal axis, the flexible conduit having a proximal end and a distal end, at least one delivery waveguide and at least one collection waveguide extending along the flexible conduit, a transmission output of the at least one delivery waveguide and a transmission input of the at least one collection waveguide located along a distal portion of the conduit. A spectrometer is connected to the at least one delivery waveguide and the at least one collection waveguide, the spectrometer configured to perform spectroscopy. A controller system is configured to calculate a distance between the flexible conduit and the wall of the body lumen based on a spectroscopic measurement of the at least one primary radiation signal that traveled between the flexible conduit and body lumen.

    摘要翻译： 提供了一种用于探测体腔的系统，所述体腔包括沿着纵向轴线伸长的柔性导管，所述柔性导管具有近端和远端，至少一个输送波导和至少一个收集波导，所述收集波导沿着柔性导管 ，所述至少一个传送波导的传输输出和沿着所述导管的远端部分定位的所述至少一个收集波导的传输输入。 分光计连接到至少一个传送波导和至少一个收集波导，分光计配置成执行光谱分析。 控制器系统被配置为基于在柔性导管和体腔之间行进的至少一个初级辐射信号的光谱测量来计算柔性导管和体腔的壁之间的距离。