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142 条记录 (耗时 0.016 秒)

    Microcoil vaso-occlusive device with multi-axis secondary configuration
    1.
    发明公开
    Microcoil vaso-occlusive device with multi-axis secondary configuration 审中-公开
    Mikrospulen-Gefäßverschlussmit mehrachsigersekundärerKonfiguration

    公开(公告)号：EP2363081A1

    公开(公告)日：2011-09-07

    申请号：EP11165088.3

    申请日：2003-01-10

    申请人： MicroVention, Inc.

    发明人： Schaefer, Dean ,  Greene, George, R., Jr. ,  Ferrera, David, A. ,  Fitz, Matthew ,  Rosenbluth, Robert, F. ,  Cox, Brian

    IPC分类号： A61B17/12

    CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/12145 ,  A61B2017/00526 ,  A61B2017/00867

    摘要： A vaso-occlusive device includes a microcoil formed into a minimum energy state secondary configuration comprising a plurality of curved segments, each defining a discrete axis, whereby the device, in its minimum energy state configuration, defines multiple axes. In a preferred embodiment, the secondary configuration-comprises a plurality of interconnected closed loops defining a plurality of discrete axes. In a second embodiment, the secondary configuration defines a wave-form like structure comprising an array of laterally-alternating open loops defining a plurality of separate axes. In a third embodiment, the secondary configuration forms a series of tangential closed loops, wherein the entire structure subtends a first angle of arc, and wherein each adjacent pair of loops defines a second angle of arc. In a fourth embodiment, the secondary configuration forms a logarithmic spiral. In all embodiments, the device, in its secondary configuration, has a dimension that is substantially larger than the largest dimension of the vascular site i.e., aneurysm in which it is to be deployed. Thus, confinement of the device within an aneurysm causes it to assume a three-dimensional configuration with a higher energy state than the minimum energy state. Because the minimum energy state configuration of the device is larger in at least one dimension than the aneurysm, the deployed device is constrained by its contact with the walls of the aneurysm from returning to its minimum energy state configuration. The engagement of the device with the aneurysm wall minimizes shifting or tumbling due to blood flow. Furthermore, the secondary configuration is not conducive to "coin stacking," thereby minimizing the compaction experienced.

    摘要翻译： 血管闭塞装置包括形成为最小能量状态次级构造的微线圈，其包括多个弯曲段，每个弯曲段限定离散轴线，由此，该装置在其最小能量状态构造中限定多个轴线。 在优选实施例中，次级配置包括限定多个离散轴线的多个互连闭合回路。 在第二实施例中，次级配置限定波形状结构，其包括限定多个单独轴线的横向交替的开放环的阵列。 在第三实施例中，次级配置形成一系列切向闭合环，其中整个结构对着第一弧形角，并且其中每个相邻的一对环限定第二弧的角度。 在第四实施例中，次级配置形成对数螺旋。 在所有实施例中，处于其二次构型的装置的尺寸基本上大于血管部位的最大尺寸，即其将被部署的动脉瘤。 因此，装置在动脉瘤内的限制使其呈现具有比最小能量状态更高能量状态的三维构型。 由于装置的最小能量状态构造在至少一个维度上比动脉瘤更大，所以展开的装置受到与动脉瘤壁的接触的约束，从而返回到其最小能量状态。 该装置与动脉瘤壁的接合最小化由于血流引起的移动或翻滚。 此外，二次配置不利于“硬币堆叠”，从而使经历的压实最小化。

    System for controlling and adjusting interstitial photodynamic light therapy parameters
    2.
    发明公开
    System for controlling and adjusting interstitial photodynamic light therapy parameters 有权
    System zurÜberwachungund Anpassung der Parameter de intrakorporalen optoynamischen Lichttherapie

    公开(公告)号：EP2298413A1

    公开(公告)日：2011-03-23

    申请号：EP10162517.6

    申请日：2007-08-15

    申请人： Spectracure AB

    发明人： Swartling, Johannes

    IPC分类号： A61N5/06 ,  A61B18/00 ,  A61B18/20 ,  A61B19/00

    CPC分类号： A61N5/062 ,  A61B2017/00022 ,  A61B2018/00642 ,  A61B2034/105 ,  A61N5/0601 ,  A61N2005/0612 ,  A61N2005/063

    摘要： A method and system for controlling and adjusting light in interstitial photodynamic light therapy (IPDT) in a subject is disclosed. More particularly, a method for controlling the light in interstitial tumor photodynamic light therapy is described using a calculation method for determination of status of tissue during the PDT treatment. The status is used in a feedback loop to control the continued PDT treatment. Methods are disclosed that constitute pre-treatment and realtime dosimetry modules for IPDT on the whole prostate glandular tissue. The method includes reconstruction of the target geometry, optimization of source fiber positions within this geometry, monitoring of the light attenuation during the treatment procedure and updating individual fiber irradiation times to take into account any variation in tissue light transmission. A control device that is arranged to restrict delivery of therapeutic light treatment at least temporary in dependence of at least one attribute of one of photodynamic treatment parameters. In comparison to no treatment feedback, a significant undertreatment of the patient as well as damage to healthy organs at risk are avoided.

    摘要翻译： 公开了一种用于控制和调节受试者中的间质性光动力光疗法（IPDT）中的光的方法和系统。 更具体地，使用用于在PDT处理期间确定组织状态的计算方法来描述用于控制间质肿瘤光动力光疗法中的光的方法。 该状态用于反馈回路以控制持续的PDT治疗。 公开了构成用于IPDT对整个前列腺腺组织的预处理和实时剂量测定模块的方法。 该方法包括重建目标几何形状，优化在该几何形状内的源光纤位置，监测处理过程中的光衰减和更新各个光纤照射时间以考虑到组织光透射中的任何变化。 一种控制装置，其被配置为根据光动力学治疗参数之一的至少一个属性至少临时地限制治疗性光处理的递送。 与没有治疗反馈相比，避免了对患者的重大治疗以及危及健康器官的损害。

    Implant, medical implant, and method for delivery of a medical implant
    3.
    发明公开
    Implant, medical implant, and method for delivery of a medical implant 有权
    Vorrichtung zur intravascularen植入

    公开(公告)号：EP2248471A1

    公开(公告)日：2010-11-10

    申请号：EP09159586.8

    申请日：2009-05-06

    申请人： Occlutech GmbH ,  Maslanka, Herbert

    发明人： Nielsen, Stevan ,  Maslanka, Herbert

    IPC分类号： A61B17/00

    CPC分类号： A61B17/3468 ,  A61B17/12022 ,  A61B17/12109 ,  A61B17/12122 ,  A61B17/12172 ,  A61B2017/00575 ,  A61B2017/12054 ,  A61F2002/9505

    摘要： An intravascular delivery device is disclosed comprising a delivery wire having a proximal and a distal end and an interior lumen extending therebetween and wherein said distal end comprises a connection interface adapted to matingly interlock with a proximal end portion of a medical implantable device, wherein said delivery device comprises a locking unit arranged to secure said connection interface in a locking position in which said medical implant is pivotably locked before a controlled release.

    摘要翻译： 公开了一种血管内输送装置，其包括具有近端和远端以及在其间延伸的内腔的输送线，并且其中所述远端包括适于与医学可植入装置的近端部分配合地互锁的连接界面，其中所述输送 装置包括锁定单元，其被布置成将所述连接界面固定在锁定位置，在该位置中，所述医疗植入物在受控释放之前可枢转地锁定。

    PATENT BREATHING MODELING
    8.
    发明公开
    PATENT BREATHING MODELING 审中-公开
    MODELLIERUNG EINER PATIENTENATMUNG

    公开(公告)号：EP2192855A2

    公开(公告)日：2010-06-09

    申请号：EP08860538.1

    申请日：2008-07-09

    申请人： Superdimension, Ltd.

    发明人： AVERBUCH, Dorian

    IPC分类号： A61B5/05

    摘要： A method of accounting for the movement of the lungs during an endoscopic procedure such that a previously acquired image may be dynamically registered with a display showing the position of a locatable guide. After an initial image set is acquired, an area of interest is identified and the movement thereof due to breathing is mathematically modeled. Patient movement sensors are then used to provide information on the patient's breathing patterns. This information is entered into the mathematical model in order to update the registration between the image set and a display showing the position of the locatable guide.

    摘要翻译： 一种在内窥镜程序期间考虑肺的移动的方法，使得先前获取的图像可以用显示可定位的引导件的位置的显示器动态地登记。 在获取初始图像集之后，识别感兴趣的区域，并且由于呼吸而导致的移动被数学地建模。 然后，患者运动传感器用于提供患者呼吸模式的信息。 该信息被输入到数学模型中，以便更新图像组和显示可定位指南的位置的显示之间的配准。

    SYSTEM, METHODS AND APPARATUS FOR CEREBRAL PROTECTION
    10.
    发明公开
    SYSTEM, METHODS AND APPARATUS FOR CEREBRAL PROTECTION 审中-公开
    系统，方法和装置ZEREBRALSCHUTZ

    公开(公告)号：EP2152352A1

    公开(公告)日：2010-02-17

    申请号：EP08769476.6

    申请日：2008-05-15

    申请人： Yacoubian, Vahe Stephan ,  Shahinian, Hrayr Karnig

    发明人： Yacoubian, Vahe Stephan ,  Shahinian, Hrayr Karnig

    IPC分类号： A61M37/00

    CPC分类号： A61M25/10 ,  A61M25/0029 ,  A61M25/1011 ,  A61M2025/0037 ,  A61M2025/004 ,  A61M2025/1052 ,  A61M2025/1095 ,  A61M2025/1097

    摘要： A device, system and method for perfusing an oxygenated medium in the cerebral vasculature. In bihemisphenc brain perfusion it includes positioning pressure cuffs on extremities, providing a catheter with a balloon, inserting the catheter into a vein, and advancing the catheter such that the balloon is positioned in the superior vena cava. During perfusion mode, the cuffs and balloon are inflated causing an increase in cerebral blood flow, retrogradely, and oxygenated blood which may be cooled is pumped from a femoral artery into the catheter for a suitable period. During non-perfusion mode the cuffs and balloon are deflated. In single hemisphere brain perfusion, it includes providing a catheter with a balloon, inserting the catheter into a vein, and advancing the catheter such that the balloon is positioned in the jugular vein on the side of the brain requiring perfusion, no pressure cuffs are needed.