公开(公告)号：EP1931800A4

公开(公告)日：2011-06-15

申请号：EP06803736

申请日：2006-09-15

申请人： ARTEMIS HEALTH INC ,  GEN HOSPITAL CORP

发明人： KAPUR RAVI ,  TONER MEHMET ,  HUANG LOTIEN RICHARD ,  BARBER TOM ,  CARVALHO BRUCE ,  GRAY DARREN ,  BALIS ULYSSES ,  WALSH JOHN ,  GRISHAM MICHAEL ,  TOMPKINS RON ,  SCHMIDT MARTIN

IPC分类号： C12Q1/68 ,  G06F19/18

CPC分类号： G01N33/80 ,  B01L3/502761 ,  B01L2200/0668 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2400/043 ,  B01L2400/0487 ,  B01L2400/086 ,  B03C2201/18 ,  B03C2201/26 ,  B82Y15/00 ,  B82Y30/00 ,  G01N1/4077 ,  G01N33/54366 ,  G01N33/569 ,  G01N33/574 ,  G01N2001/4088 ,  G01N2333/805 ,  G01N2800/387 ,  G06F19/18

公开(公告)号：EP2024513A4

公开(公告)日：2010-01-20

申请号：EP07784444

申请日：2007-06-14

申请人： ARTEMIS HEALTH INC ,  CELLECTIVE DX CORP ,  GEN HOSPITAL CORP

发明人： SHOEMAKER DANIEL ,  TONER MEHMET ,  KAPUR RAVI ,  STOUGHTON ROLAND ,  DAVIS RONALD W

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6883 ,  C12Q2600/156 ,  C12Q2600/158 ,  C12Q2600/16

公开(公告)号：EP2024512A4

公开(公告)日：2009-12-09

申请号：EP07784442

申请日：2007-06-14

申请人： ARTEMIS HEALTH INC ,  CELLECTIVE DX CORP ,  GEN HOSPITAL CORP

发明人： KAPUR RAVI ,  TONER MEHMET ,  WANG ZIHUA ,  FUCHS MARTIN

IPC分类号： C12Q1/68 ,  C12P19/34 ,  G01N33/48

CPC分类号： C12Q1/6806 ,  C12Q1/6883 ,  C12Q2600/156 ,  C12Q2600/158 ,  C12Q2600/16 ,  G01N2015/1006 ,  G01N2015/1087

公开(公告)号：EP1931800A2

公开(公告)日：2008-06-18

申请号：EP06803736.5

申请日：2006-09-15

申请人： Artemis Health, Inc. ,  THE GENERAL HOSPITAL CORPORATION

发明人： KAPUR, Ravi ,  TONER, Mehmet ,  HUANG, Lotien, Richard ,  BARBER, Tom ,  CARVALHO, Bruce ,  GRAY, Darren ,  BALIS, Ulysses ,  WALSH, John ,  GRISHAM, Michael ,  TOMPKINS, Ron ,  SCHMIDT, Martin

IPC分类号： C12Q1/68

CPC分类号： G01N33/80 ,  B01L3/502761 ,  B01L2200/0668 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2400/043 ,  B01L2400/0487 ,  B01L2400/086 ,  B03C2201/18 ,  B03C2201/26 ,  B82Y15/00 ,  B82Y30/00 ,  G01N1/4077 ,  G01N33/54366 ,  G01N33/569 ,  G01N33/574 ,  G01N2001/4088 ,  G01N2333/805 ,  G01N2800/387 ,  G06F19/18

摘要： The invention relates to one or more size-based separation modules adapted to increase a concentration of a first analyte in a sample by at least 10,000 fold, wherein said first analyte has an initial concentration in said sample of less than 1 x 10 -3 analytes/µL, and an analyzer for analyzing said first analytes in an enriched medium. Methods of using the separation modules for identifying a characteristic associated with a condition in a patient e.g. a fetal abnormality are also provided.

公开(公告)号：EP1934326A2

公开(公告)日：2008-06-25

申请号：EP06814753.7

申请日：2006-09-15

申请人： Artemis Health, Inc. ,  THE GENERAL HOSPITAL CORPORATION

发明人： KAPUR, Ravi ,  HUANG, Lotien, Richard ,  BARBER, Tom ,  CARVALHO, Bruce, L. ,  TONER, Mehmet ,  SCHMIDT, Martin

IPC分类号： C12M1/34 ,  G01N33/53

CPC分类号： B01L3/502753 ,  B01L3/502746 ,  B01L3/502776 ,  B01L2200/0647 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2400/0406 ,  B01L2400/0409 ,  B01L2400/0415 ,  B01L2400/043 ,  B01L2400/0487 ,  B01L2400/086 ,  B03C1/30 ,  B03C1/32 ,  B03C2201/18 ,  C12M35/06 ,  G01N33/5044

摘要： The invention features devices and methods for the enrichment of cells and other desired analytes by employing a magnetic field, alone or in conjunction with size-based separation. The devices and methods may be advantageously employed to enrich for rare cells, e.g., fetal cells or epithelial cells, present in a sample, e.g., maternal blood.