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公开(公告)号：EP4225335A1
公开(公告)日：2023-08-16
申请号：EP21878591.3
申请日：2021-10-08
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公开(公告)号：EP4034371A1
公开(公告)日：2022-08-03
申请号：EP20869054.5
申请日：2020-09-25
IPC分类号： B29C64/20 , B29C64/10 , B29C64/245 , B29C64/379 , B29C64/40 , B29C67/00
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公开(公告)号：EP3948705A1
公开(公告)日：2022-02-09
申请号：EP20784488.7
申请日：2020-03-26
发明人： SCHULTZ, Alex , JOHNSON, Jeromy , ELI, Robert
IPC分类号： G06N20/10 , B29C64/10 , B29C64/25 , B29C64/30 , B29C64/393
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4.发明公开VASCULARIZED IN VITRO PERFUSION DEVICES, METHODS OF FABRICATING, AND APPLICATIONS THEREOF 审中-公开血管化的体外灌注装置，制造方法及其应用
公开(公告)号：EP3319651A1
公开(公告)日：2018-05-16
申请号：EP16821889.9
申请日：2016-07-06
CPC分类号： C12M29/10 , C12M23/16 , C12M25/14 , G01N33/502 , G01N33/5064
摘要： A bona fide adaptable in vitro microcirculation model is provided by integrating a 3-D printed network of endothelial-cell lined perfusion channels, formed via sacrificial casting in a gel matrix, with a native, adaptable microvasculature matured from native microvessels added to the gel matrix. Responsive vascular adaptation exhibited by the in vitro microcirculation is physiologically relevant. Methods for fabricating, devices, models and investigative platforms for pharmaceutical applications, vascular mechanism and microvessel-parenchyma interaction studies, and vascularizing strategies for tissue engineering applications are also disclosed.
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公开(公告)号：EP3691841A1
公开(公告)日：2020-08-12
申请号：EP18864753.1
申请日：2018-10-05
发明人： CAMBRON, Scott Douglas , ELI, Kyle
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6.发明公开
公开(公告)号：EP3691862A1
公开(公告)日：2020-08-12
申请号：EP18865267.1
申请日：2018-10-05
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7.发明公开SYSTEM AND WORKSTATION FOR THE DESIGN, FABRICATION AND ASSEMBLY OF BIO-MATERIAL CONSTRUCTS 审中-公开体制和工作从生物材料的设计，生产和组装构建
公开(公告)号：EP3055133A1
公开(公告)日：2016-08-17
申请号：EP14851795.6
申请日：2014-10-10
发明人： GOLWAY, Michael , PALMER, Justin, C. , ELI, Jeffrey, Kyle , BARTLETT, Joshua, D. , COLLINS, Ellsworth, H.
IPC分类号： B33Y30/00
CPC分类号： G06F17/50 , B25J9/1679 , B29C64/106 , B29L2031/7532 , C12M21/08 , C12M33/00 , G05B19/4099 , G06F17/5009 , Y02P90/265 , Y10S901/02 , Y10S901/30
摘要： A bioassembly system having a tissue/object modeling software component fully and seamlessly integrated with a robotic bioassembly workstation component for the computer-assisted design, fabrication and assembly of biological and non-biological constructs. The robotic bioassembly workstation includes a six-axis robot providing the capability for oblique-angle printing, printing by non-sequential planar layering, and printing on print substrates having variable surface topographies, enabling fabrication of more complex bio-constructs including tissues, organs and vascular trees.
摘要翻译： 具有组织/对象建模软件组分A bioassembly系统具有用于生物和非生物构建体的计算机辅助设计，制造和装配的机器人工作站bioassembly组分充分和无缝集成。 机器人bioassembly工作站包括一个六轴机器人提供斜角印刷，通过非顺序平面分层印刷，印刷能力印刷基板上具有可变的表面形貌，使更复杂的生物构建体包含组织，器官和制造 血管树。
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公开(公告)号：EP4037891A1
公开(公告)日：2022-08-10
申请号：EP20870666.3
申请日：2020-10-02
IPC分类号： B29C64/209 , B01F11/00 , B22F3/093 , B29C64/10 , B29C64/20 , B29C64/227
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公开(公告)号：EP3952893A1
公开(公告)日：2022-02-16
申请号：EP20786943.9
申请日：2020-04-09
发明人： HOYING, James , STROBEL, Hannah , BUSHMAN, Sarah
IPC分类号： A61K35/30 , C12N15/113 , G01N33/50
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10.发明公开SYSTEM AND WORKSTATION FOR THE DESIGN, FABRICATION AND ASSEMBLY OF BIO-MATERIAL CONSTRUCTS 审中-公开SYSTEM UND ARBEITSPLATZFÜRDEN ENTWURF，DIE HERSTELLUNG ANDD MONTAGE VON KONSTRUKTEN AUS BIOMATERIAL
公开(公告)号：EP3055133A4
公开(公告)日：2017-07-19
申请号：EP14851795
申请日：2014-10-10
IPC分类号： B33Y30/00 , B25J9/16 , B29C67/00 , G05B19/4099 , G06F17/50
CPC分类号： G06F17/50 , B25J9/1679 , B29C64/106 , B29L2031/7532 , C12M21/08 , C12M33/00 , G05B19/4099 , G06F17/5009 , Y02P90/265 , Y10S901/02 , Y10S901/30
摘要： A bioassembly system having a tissue/object modeling software component fully and seamlessly integrated with a robotic bioassembly workstation component for the computer-assisted design, fabrication and assembly of biological and non-biological constructs. The robotic bioassembly workstation includes a six-axis robot providing the capability for oblique-angle printing, printing by non-sequential planar layering, and printing on print substrates having variable surface topographies, enabling fabrication of more complex bio-constructs including tissues, organs and vascular trees.
摘要翻译： 具有组织/对象建模软件组件的生物组装系统完全且无缝地与机器人生物组件工作站组件完全集成，用于计算机辅助设计，制造和组装生物和非生物构建体。 机器人生物组装工作站包括一个六轴机器人，可提供倾斜角度打印功能，通过非连续的平面分层打印以及在具有可变表面形貌的打印基材上打印，可制作更复杂的生物构造，包括组织，器官和 血管树。
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