-
公开(公告)号：EP2507220A4
公开(公告)日：2013-05-01
申请号：EP10834885
申请日：2010-08-04
申请人： BIOTIUM INC
发明人： MAO FEI , LEUNG WAI-YEE , CHEUNG CHING-YING , HOOVER HYE EUN
IPC分类号： C07D311/00 , A61K49/00 , C07D335/00 , C07D491/22
CPC分类号： C07H15/26 , A61K49/0017 , C07D311/88 , C07D405/04 , C07D405/14 , C07D491/147 , C07D491/22 , C07F9/65586 , C07K1/13 , C07K16/00 , C07K16/2809 , C07K16/32 , Y10T436/25
摘要： The present invention relates to fluorescent dyes in general. The present invention provides a wide range of fluorescent dyes and kits containing the same, which are applicable for labeling a variety of biomolecules, cells and microorganisms. The present invention also provides various methods of using the fluorescent dyes for research and development, forensic identification, environmental studies, diagnosis, prognosis, and/or treatment of disease conditions.
-
2.发明公开Dimeric and trimeric nucleic acid dyes, and associated systems and methods 有权DimereNucleinsäurefarbstoffeundzugehörigeSysteme und Verfahren
公开(公告)号：EP2428586A1
公开(公告)日：2012-03-14
申请号：EP11175090.7
申请日：2006-03-17
发明人： Mao, Fei , Leung, Wai-Yee , Xin, Xing
IPC分类号： C12Q1/68 , C07D401/02 , C07D213/02 , C07D209/08 , C07D213/38 , C07D221/10 , C07D417/14 , C07D417/06 , C09B15/00 , C07D491/147
CPC分类号： C12Q1/6876 , C07D209/08 , C07D213/38 , C07D221/10 , C07D417/06 , C07D417/14 , C07D491/147 , C07H21/00 , C09B15/00 , C12Q1/6851 , C12Q1/686 , C12Q2563/173
摘要： Dimeric and trimeric nucleic acid dyes, and associated systems and methods are provided. Such a dye may form a hairpin-like structure that enables it to stain nucleic acids via a release-on-demand mechanism, for example. Such a dye may have low background fluorescence in the absence of nucleic acids and high fluorescence in the presence of nucleic acids, upon binding therewith, for example. A dye provided herein may be useful in a variety of applications, such as in DNA quantitation in real-time PCR, for example.
摘要翻译： 提供二聚和三聚体核酸染料以及相关系统和方法。 这样的染料可以形成发夹状结构，使其能够通过例如按需释放机制来染色核酸。 例如，这种染料在不存在核酸的情况下可能具有低背景荧光，并且在核酸存在时具有高荧光。 本文提供的染料可用于各种应用，例如在实时PCR中的DNA定量中。
-
公开(公告)号：EP2507220B1
公开(公告)日：2016-10-05
申请号：EP10834885.5
申请日：2010-08-04
申请人： Biotium, Inc.
发明人： MAO, Fei , LEUNG, Wai-Yee , CHEUNG, Ching-Ying , HOOVER, Hye Eun
IPC分类号： C07D311/88 , C07D405/04 , C07D491/22 , A61K49/00
CPC分类号： C07H15/26 , A61K49/0017 , C07D311/88 , C07D405/04 , C07D405/14 , C07D491/147 , C07D491/22 , C07F9/65586 , C07K1/13 , C07K16/00 , C07K16/2809 , C07K16/32 , Y10T436/25
摘要： The present invention relates to fluorescent dyes in general. The present invention provides a wide range of fluorescent dyes and kits containing the same, which are applicable for labeling a variety of biomolecules, cells and microorganisms. The present invention also provides various methods of using the fluorescent dyes for research and development, forensic identification, environmental studies, diagnosis, prognosis, and/or treatment of disease conditions.
摘要翻译： 本发明一般涉及荧光染料。 本发明提供了广泛的荧光染料和含有它们的试剂盒，其可应用于标记各种生物分子，细胞和微生物。 本发明还提供了用于研究和开发，法医鉴定，环境研究，诊断，预后和/或治疗疾病状况的各种荧光染料的方法。
-
4.发明公开FLUORESCENT DYES, FLUORESCENT DYE KITS, AND METHODS OF PREPARING LABELED MOLECULES 有权荧光染料，FLUORESZENZFARBSTOFFKITS及其制造方法标记的分子
公开(公告)号：EP2686680A4
公开(公告)日：2014-12-10
申请号：EP12761364
申请日：2012-03-16
申请人： BIOTIUM INC
发明人： MAO FEI , LEUNG WAI-YEE , CHEUNG CHING-YING , HOOVER HYE EUN
IPC分类号： G01N33/50 , G01N33/543 , G01N33/58
CPC分类号： G01N1/30 , C07K1/13 , C07K17/06 , C09B11/24 , C09B23/06 , C09B23/083 , C09B57/001 , C09B57/02 , G01N33/53 , G01N33/532 , G01N33/533 , G01N33/582 , G01N33/6854
摘要： The present invention provides methods, compositions, and kits useful in preparing labeled molecules, which are useful in the detection of binding partners.
-
公开(公告)号：EP2428586B1
公开(公告)日：2013-05-08
申请号：EP11175090.7
申请日：2006-03-17
发明人： Mao, Fei , Leung, Wai-Yee , Xin, Xing
IPC分类号： C12Q1/68 , C07D401/02 , C07D213/02 , C07D209/08 , C07D213/38 , C07D221/10 , C07D417/14 , C07D417/06 , C09B15/00 , C07D491/147
CPC分类号： C12Q1/6876 , C07D209/08 , C07D213/38 , C07D221/10 , C07D417/06 , C07D417/14 , C07D491/147 , C07H21/00 , C09B15/00 , C12Q1/6851 , C12Q1/686 , C12Q2563/173
-
公开(公告)号：EP2393805A4
公开(公告)日：2012-09-19
申请号：EP10739088
申请日：2010-02-03
申请人： BIOTIUM INC
发明人： MAO FEI , LEUNG WAI-YEE , CHEUNG CHING-YING
IPC分类号： C07D311/88 , C07D405/12 , C07D405/14 , C07D491/22 , C07K1/13
CPC分类号： G01N33/57484 , C07D311/88 , C07D405/12 , C07D405/14 , C07D491/147 , C07D491/22 , C07K1/13 , G01N33/582
摘要： The present invention relates to fluorescent dyes in general. The present invention provides a wide range of fluorescent dyes and kits containing the same, which are applicable for labeling a variety of biomolecules, cells and microorganisms. The present invention also provides various methods of using the fluorescent dyes for research and development, forensic identification, environmental studies, diagnosis, prognosis, and/or treatment of disease conditions.
-
公开(公告)号：EP2393805A1
公开(公告)日：2011-12-14
申请号：EP10739088.2
申请日：2010-02-03
申请人： Biotium Inc.
发明人： MAO, Fei , LEUNG, Wai-Yee , CHEUNG, Ching-Ying
IPC分类号： C07D405/00
CPC分类号： G01N33/57484 , C07D311/88 , C07D405/12 , C07D405/14 , C07D491/147 , C07D491/22 , C07K1/13 , C09B11/24 , G01N33/582
摘要： The present invention relates to fluorescent dyes in general. The present invention provides a wide range of fluorescent dyes and kits containing the same, which are applicable for labeling a variety of biomolecules, cells and microorganisms. The present invention also provides various methods of using the fluorescent dyes for research and development, forensic identification, environmental studies, diagnosis, prognosis, and/or treatment of disease conditions.
-
8.发明授权DIMERIC AND TRIMERIC NUCLEIC ACID DYES, AND ASSOCIATED SYSTEMS AND METHODS 有权二聚体和三聚NUCLEIC染料和系统和方法，通过连接
公开(公告)号：EP1863933B1
公开(公告)日：2011-10-05
申请号：EP06738900.7
申请日：2006-03-17
发明人： MAO, Fei , LEUNG, Wai-Yee , XIN, Xing
IPC分类号： C12Q1/68 , C07D401/02 , C07D213/02
CPC分类号： C12Q1/6876 , C07D209/08 , C07D213/38 , C07D221/10 , C07D417/06 , C07D417/14 , C07D491/147 , C07H21/00 , C09B15/00 , C12Q1/6851 , C12Q1/686 , C12Q2563/173
摘要： Dimeric and trimeric nucleic acid dyes, and associated systems and methods are provided. Such a dye may form a hairpin-like structure that enables it to stain nucleic acids via a release-on-demand mechanism, for example. Such a dye may have low background fluorescence in the absence of nucleic acids and high fluorescence in the presence of nucleic acids, upon binding therewith, for example. A dye provided herein may be useful in a variety of applications, such as in DNA quantitation in real-time PCR, for example.
-
公开(公告)号：EP2223086A4
公开(公告)日：2011-05-04
申请号：EP08861025
申请日：2008-12-12
申请人： BIOTIUM INC
发明人： MAO FEI , LEUNG WAI-YEE , CHEUNG CHING-YING , HOOVER HYE EUN
CPC分类号： G01N33/582 , C09B11/08 , C09B11/24 , C09B23/0066 , C09B23/06 , C09B23/083 , C09B23/086 , C09B57/001 , C09B57/02 , C09B69/00 , G01N21/6428 , G01N2021/6439
摘要： The present invention relates to fluorescent dyes. The present invention provides a wide range of fluorescent dyes and kits containing the same, which are applicable for labeling a variety of biomolecules, cells and microorganisms. In one aspect, the invention provides a compound having a maximal fluorescence excitation wavelength, wherein the compound has a structure of Formula II: F—Y=Ψ Formula II and wherein Z— is a counterion, Y is a bridge unit permitting electron delocalization between F and Ψ, and F is a moiety having the structure: The present invention also provides various methods of using the fluorescent dyes for research and development, forensic identification, environmental studies, diagnosis, prognosis, and/or treatment of disease conditions.
-
10.发明公开DIMERIC AND TRIMERIC NUCLEIC ACID DYES, AND ASSOCIATED SYSTEMS AND METHODS 有权二聚体和三聚NUCLEIC染料和系统和方法，通过连接
公开(公告)号：EP1863933A4
公开(公告)日：2009-04-08
申请号：EP06738900
申请日：2006-03-17
发明人： MAO FEI , LEUNG WAI-YEE , XIN XING
IPC分类号： C12Q1/68 , C07D213/02 , C07D401/02
CPC分类号： C12Q1/6876 , C07D209/08 , C07D213/38 , C07D221/10 , C07D417/06 , C07D417/14 , C07D491/147 , C07H21/00 , C09B15/00 , C12Q1/6851 , C12Q1/686 , C12Q2563/173
摘要： Dimeric and trimeric nucleic acid dyes, and associated systems and methods are provided. Such a dye may form a hairpin-like structure that enables it to stain nucleic acids via a release-on-demand mechanism, for example. Such a dye may have low background fluorescence in the absence of nucleic acids and high fluorescence in the presence of nucleic acids, upon binding therewith, for example. A dye provided herein may be useful in a variety of applications, such as in DNA quantitation in real-time PCR, for example.
-
-
-
-
-
-
-
-
-
搜索结果
19 条记录 (耗时 0.019 秒)
