公开(公告)号：EP2049907B1

公开(公告)日：2011-09-14

申请号：EP07823350.9

申请日：2007-07-26

申请人： C2 DIAGNOSTICS

发明人： CHAMPSEIX, Henri ,  CHAMPSEIX, Serge ,  MILHAT, Jean-Pierre

IPC分类号： G01N35/10 ,  G01N1/00

CPC分类号： G01N35/1079 ,  Y10T436/2575

摘要： The device according to the invention comprises a body (14), a needle (10), sealing means (11) and means (121, 122) for conveying and evacuating a liquid. The needle (10) comprises at least one groove (101) located between the sealing means (11) and the sampling end (103) of the needle (10). The sampling end (103) includes a sampling orifice (102) leading to the side wall of that end. The device according to the invention makes it possible to mitigate the leakage problems encountered in the prior art by resolving the problems of placing the interior of a tube, containing a product to be analyzed, at atmospheric pressure.

公开(公告)号：EP1866651A2

公开(公告)日：2007-12-19

申请号：EP06726120.6

申请日：2006-03-22

申请人： C2 DIAGNOSTICS

发明人： CHAMPSEIX, Henri ,  GIRAUD, Jérôme

IPC分类号： G01N33/72 ,  G01N33/50

CPC分类号： G01N33/721 ,  G01N15/1404 ,  G01N15/1459 ,  G01N33/5094 ,  G01N2015/008 ,  G01N2015/1006 ,  G01N2015/1486 ,  Y10T436/10 ,  Y10T436/101666 ,  Y10T436/107497 ,  Y10T436/108331 ,  Y10T436/25 ,  Y10T436/25625

摘要： The invention concerns a method for analyzing a blood sample, including the following steps: forming in a single so-called diluting and analyzing vessel an analysis solution containing said blood sample, a diluent, and at: least one compound for lysing the red blood cells; at least one compound for stabilizing hemoglobin in the form of a chromogenic complex; measuring on said analysis solution in said vessel after lysis of the red blood cells the hemoglobin level by spectrophotometry; and drawing an appropriate amount of said analysis solution in said vessel whereon a leukocyte differentiation is performed by an optical means. The invention is characterized in that the analysis solution further contains at least one compound to protect the white blood cells, enabling at least four main leukocyte subpopulations to be discriminated. The invention also concerns a hematological apparatus for implementing said method.

公开(公告)号：EP1866623A1

公开(公告)日：2007-12-19

申请号：EP06726121.4

申请日：2006-03-22

申请人： C2 DIAGNOSTICS

发明人： CHAMPSEIX, Henri

IPC分类号： G01N15/14

CPC分类号： G01N15/1404 ,  G01N15/1459 ,  G01N2015/1409

摘要： The invention concerns a device (100) comprising means (302, 106) for injecting a blood sample flow in a circulating optical vessel (300) to create a liquid tubing flow (303) around the sample flow, with a tubing liquid. The invention is characterized in that it comprises means (134, 150) for regulating a sample flow rate relative to the tubing flow rate.

公开(公告)号：EP1866622A1

公开(公告)日：2007-12-19

申请号：EP06726118.0

申请日：2006-03-22

申请人： C2 DIAGNOSTICS

发明人： MAGNIN, Olivier ,  DAMONNEVILLE, Laurent ,  CHAMPSEIX, Serge

IPC分类号： G01N15/14

CPC分类号： G01N15/1456 ,  G01N15/1434 ,  G01N2015/1486

摘要： The invention concerns an optical device (200) adapted in particular for leukocyte counting and differentiation in a blood analyzing automaton and comprising a LED-type light source (201) for illuminating a blood sample (311) which flows in an optical vessel.

公开(公告)号：EP1660857A2

公开(公告)日：2006-05-31

申请号：EP04767696.0

申请日：2004-07-16

申请人： C2 DIAGNOSTICS

发明人： CHAMPSEIX, Serge ,  CHAMPSEIX, Henri

IPC分类号： G01N1/00

CPC分类号： G01N35/1079

摘要： The inventive method and device for an automatic analyser, in particular for blood analysis sampling consists in displacing a sampling needle (5) rotatable around an axis (X2) which forms an angle with said sampling needle. Said method and device are particularly suitable for use in a small blood sampling automate.

公开(公告)号：EP2352984A1

公开(公告)日：2011-08-10

申请号：EP09801729.6

申请日：2009-12-01

申请人： C2 DIAGNOSTICS

发明人： CHAMPSEIX, Henri ,  MAGNIN, Olivier ,  WELMANT, Bernard

IPC分类号： G01N15/12 ,  G01N15/14

CPC分类号： G01N15/1209 ,  G01N15/1056 ,  G01N15/1227 ,  G01N15/14 ,  G01N15/1404 ,  G01N15/1429 ,  G01N15/1456 ,  G01N15/1459 ,  G01N15/1463 ,  G01N15/1484 ,  G01N33/4915 ,  G01N2015/008 ,  G01N2015/1037

摘要： The invention relates to a method and to a device used to carry out a flow cytometry method, preferably intended for, but not limited to, the counting and differentiation of white blood cells. More specifically, the invention relates to the field of simplified hematology devices with low operating costs. According to the invention, the method is characterised in that an impedance measurement technique is used to identify particles having a trajectory that has not passed through a predetermined optical measurement area so as to treat said particles selectively, thereby eliminating the use of sheath fluids in order to guide the particles toward the measurement area.

公开(公告)号：EP2852843A1

公开(公告)日：2015-04-01

申请号：EP13728981.5

申请日：2013-05-17

申请人： C2 DIAGNOSTICS

发明人： CHAMPSEIX, Henri

IPC分类号： G01N35/08 ,  G01N35/10 ,  B01L3/00 ,  G01N35/00

CPC分类号： B01L3/563 ,  B01L3/565 ,  G01N35/00029 ,  G01N35/085 ,  G01N35/1002 ,  G01N35/1095

摘要： The present invention concerns a fluid connection device for biological analysis apparatuses, intended to simultaneously connect a plurality of fluid conduits (10) and at least one fluidic component (3) comprising a connecting surface with a plurality of fluid ports (11), said device comprising: (i) a holding plate (1), (ii) removable attachment means (5) capable of pressing said holding plate (1) against said connecting surface, (iii) connectors (2) suitable for being fixed to the ends of the fluid conduits (10) and provided with sealing means (4) suitable for allowing a sealed connection to be made between said connectors (2) and said fluid ports (11), said holding plate (1) comprising through-openings opposite the fluid ports (11) and being shaped in such a way as to be able to receive said connectors (2) in said through-openings and to hold them pressed against the connecting surface. The invention also concerns a biological analysis apparatus implementing said device.

摘要翻译： 为生物分析设备提供一种流体连接装置，用于同时连接多个流体导管和包括连接表面的至少一个流体组件与多个流体端口，该装置具有：（i）保持板，（ii） ）可移除的连接结构，其能够将保持板压靠在连接表面上，（iii）适于固定到流体导管端部并具有适于允许在连接器和流体之间进行密封连接的密封件的连接器 端口，保持板包括与流体端口相对的通孔，并且形成为能够将连接器接收在通孔中并将其压靠在连接表面上。 还提供了实现该装置的生物分析装置。

公开(公告)号：EP1866624A1

公开(公告)日：2007-12-19

申请号：EP06726122.2

申请日：2006-03-22

申请人： C2 DIAGNOSTICS

发明人： MAGNIN, Olivier ,  CHAMPSEIX, Henri ,  CHAMPSEIX, Serge

IPC分类号： G01N15/14

摘要： The invention concerns a circulation vessel (300) adapted to an optical device (120) for leukocyte counting and/or differentiation in a blood analyzing automaton. The invention is characterized in that in an analyzing zone of the vessel (403), the cross section of the vessel has at least one transverse dimension ranging between 1 and 5 millimeters. It can advantageously be made, at least partly, from an injected plastic material and comprises at least one lens (302) molded in one single piece with the vessel (300).

公开(公告)号：EP1687607A1

公开(公告)日：2006-08-09

申请号：EP04805272.4

申请日：2004-10-22

申请人： C2 DIAGNOSTICS

发明人： CHAMPSEIX, Serge ,  CHAMPSEIX, Henri

IPC分类号： G01N1/00

CPC分类号： G01N35/1097 ,  G01N35/1065

摘要： The invention relates to a syringe block (1) comprising a plurality of syringes (2) and a collector (3), the syringes each having a suction volume, and the collector comprising electromagnetic valves. First tubes directly link the electromagnetic valves to the internal volumes and second tubes extend from the electromagnetic valves towards the containers for the sample and/or other liquids, at least one of the syringes being an air pump (15,16). The syringe block can be used as a support for various components used for the operation thereof, and can be arranged in a climatic condition reproducer. One such syringe block is especially adapted to be used in a liquid analyser, the air pump being used especially to take a sample and/or to drain and clean different recipients containing a sample.

摘要翻译： 具有多个注射器（2）和收集器（3）的用于自动分析，特别是血液的注射器块具有用于其操作的电动阀（31）。 注射器具有至少一个注射器（15,16）的空气泵，以形成承受压力的样品。

公开(公告)号：EP2092347B1

公开(公告)日：2017-05-17

申请号：EP07858452.1

申请日：2007-10-16

申请人： C2 DIAGNOSTICS

发明人： CHAMPSEIX, Serge ,  CHAMPSEIX, Henri ,  DAMONNEVILLE, Laurent

IPC分类号： G01N35/04 ,  G01N35/10

CPC分类号： G01N35/04 ,  G01N35/1079 ,  G01N2035/00524