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    AUTOSEGMENTATION/AUTOCONTOURING SYSTEM AND METHOD FOR USE WITH THREE-DIMENSIONAL RADIATION THERAPY TREATMENT PLANNING
    3.
    发明公开
    AUTOSEGMENTATION/AUTOCONTOURING SYSTEM AND METHOD FOR USE WITH THREE-DIMENSIONAL RADIATION THERAPY TREATMENT PLANNING 失效
    自分割/轮廓提取系统和使用在规划放射治疗程序

    公开(公告)号：EP0965104A1

    公开(公告)日：1999-12-22

    申请号：EP98910136.0

    申请日：1998-03-03

    申请人： Computerized Medical Systems, Inc.

    发明人： HIBBARD, Lyn

    IPC分类号： G06T5 ,  A61N5

    CPC分类号： G06T7/0012 ,  A61N5/103 ,  G06T7/12 ,  G06T7/143 ,  G06T2207/10081 ,  G06T2207/20056 ,  G06T2207/30004 ,  G06T2207/30061

    摘要： An autosegmentation/autocontouring method that may be used for quickly and accurately contouring the regions and boundaries around regions for the development of cross sections that may be linearly disposed for the three-dimensional reconstruction of an image is described and claimed. The autosegmentation/autocontouring method includes at least four steps. The first step is to digitize a CT, MRI, or other suitable image and display it on a display screen. The two-dimensional image on the display screen will include gray-scale representations of the internal organs and tissue masses of the anatomical site through which the cross section was made. The second step is to select the interior of a ROI and draw a polygon within the boundaries of the cross-sectional view of this ROI. This polygon could also be drawn in the interior of a cancerous mass or other diseased tissue. The third step of the method of the present invention is to expand the polygon in a novel manner by iteratively testing pixels of the image on the display outside of, but adjacent to, the pixels that the polygon currently subtends. Pixels will be added to the polygon if the value of a decision rule function has a predetermined value. The expansion of the polygon is continued until none of the pixels at the perimeter of the polygon can satisfy the decision rule. Once it is found that none of the perimeter pixels satisfy the decision rule, the perimeter of the polygon is considered the boundary of the ROI. And the fourth step is that the boundary of the ROI is computed and a contour is developed based on this boundary. This same process is repeated for other ROIs that the user may select.

    摘要翻译： 一种系统和方法，光盘游离缺失用于自动地计算表示对象的边界轮廓在三维断层图像也可以通过计算机断层摄影（“CT”），磁共振成像（“MRI”），正电子发射断层摄影术（“PET”来形成 ），单质子发射计算机断层摄影（“SPECT”），或其他合适的方法。 该系统和方法将首先提供该对象的内部和单个区域在一个逐步的方式被膨胀的样品区域。 在每一步，一个轮廓最大限度匹配的区域的当前边缘，局部灰度梯度最大值，和现有的轮廓形状是确定的开采。 在区域扩展结束后，对象轮廓被设置为没有具有一个目标函数求和从区域的边缘，梯度的边缘，和现有形状的贡献的最大值步骤轮廓。 两个区域和所述扩张的边界轮廓确定配制寻求thatthere是在轮廓的确定有保障的最小平均误差。 该轮廓被表示为，其中轮廓的尺寸和形状是由参数的值所指定的参数曲线。 这些参数的目标函数的自变量。 因此，该参数被认为是能够编码的轮廓形状的分布的随机变量，并且通过取特定分布，形状约束的目标函数的贡献可以被计算。 将得到的轮廓对应于所述一组参数的量，目标函数为最大。

    MULTI-VIEW IMAGE REGISTRATION
    6.
    发明公开
    MULTI-VIEW IMAGE REGISTRATION 审中-公开
    图像配准从不同的角度

    公开(公告)号：EP1285406A2

    公开(公告)日：2003-02-26

    申请号：EP00950689.0

    申请日：2000-07-26

    申请人： Computerized Medical Systems, Inc.

    发明人： HIBBARD, Lyn ,  LANE, Derek G.

    IPC分类号： G06T1/00

    CPC分类号： G06T3/0006

    摘要： A system and method for autofusion of three-dimensional ('3-D') image data volumes is described. According to the system and method, registration is effected by simultaneously displaying on a GUI at least, but preferably, two 3-D, image data volumes, and one of the 3-D image data volumes is held fixed while the other may be scaled, rotated, and translated to align homologous anatomic features. The system and method will simultaneously display the axial, sagittal, and coronal plane views of a region of a region of interest. These plane views will be of data volumes that are designed and configured for a system user to 'drag' or 'position' one volume to a new position in one plane view which will also simultaneously update the data volume in the other two plane views with no apparent lag time. The system and method also includes automated alignment computation based on mutual information (MI) maximization. The system and method aligns 3-D more efficiently and faster than prior image alignment methods.

    AUTOSEGMENTATION / AUTOCONTOURING SYSTEM AND METHOD
    9.
    发明公开
    AUTOSEGMENTATION / AUTOCONTOURING SYSTEM AND METHOD 有权
    自分割/轮廓提取制度和相关程序

    公开(公告)号：EP1080449A1

    公开(公告)日：2001-03-07

    申请号：EP99925914.6

    申请日：1999-05-27

    申请人： Computerized Medical Systems, Inc.

    发明人： HIBBARD, Lyn

    IPC分类号： G06T5/00

    摘要： A system and method is disclosed for automatically computing contours representing the boundaries of objects in three-dimensional tomographic images that may be formed by computed tomography ('CT'), magnetic resonance imaging ('MRI'), positron emission tomography ('PET'), single proton emission computed tomography ('SPECT'), or other appropriate methods. The system and method begin with a sample region of the object's interior and the single region is expanded in a stepwise fashion. At each step, a contour maximally matching the region's current edge, local gray-level gradient maxima, and prior contour shapes is determined. Upon completion of region expansion, the object contour is set to that step-contour having the maximum value of an objective function summing contributions from region edges, gradient edges, and prior shapes. Both the region expansion and the boundary contour determination are formulated such that there is a guaranteed average minimum error in the determination of the contours. This contour is represented as a parametric curve in which the contour size and shape are specified by the values of the parameters. These parameters are independant variables of the objective function. The parameters also are considered to be random variables capable of encoding a distribution of contour shapes, and by assuming a particular distribution, the contribution of shape constraints to the object function can be computed. The resulting contour corresponds to the set of parameters for which the objective function is a maximum.