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公开(公告)号：EP2274323A1
公开(公告)日：2011-01-19
申请号：EP09731344.9
申请日：2009-04-07
IPC分类号： C07K14/47 , C07K7/08 , C07K14/025
CPC分类号： C07K7/08 , C07K14/001 , C07K14/47 , C07K2319/00 , C07K2319/21 , C07K2319/23 , C07K2319/41 , C07K2319/42 , C07K2319/43 , G01N33/56983 , G01N2333/025 , G01N2500/00
摘要： The present invention is concerned with means and methods for diagnosing or treating HPV associated neoplasia or tumors. Specifically, it relates to a peptide comprising an amino acid sequence motif as shown in SEQ ID No: 1. Moreover, contemplated by the present invention are fusion polypeptides, polynucleotides, vectors and host cells based on said peptide. Furthermore, the peptides, fusion polypeptides, polynucleotides, and vectors are suitable as pharmaceutical compositions for treating HPV associated neoplasia or tumors. The peptides and fusion polypeptides are also suitable as diagnostic compositions for diagnosing HPV associated neoplasia or tumors. The present invention also refers to a method of identifying a compound capable of binding to the HPV E6 protein. Finally, a kit is provided for carrying out the aforementioned diagnosis or compound identification.
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公开(公告)号：EP2170956A2
公开(公告)日：2010-04-07
申请号：EP08759230.9
申请日：2008-06-13
发明人： GAST, Daniela , ALTEVOGT, Peter , MOLDENHAUER, Gerhard , BREITLING, Frank , KRÜGER, Achim , WOLTERINK, Silke , LÜTTGAU, Sandra , MÖBIUS, Ulrich , LI, Yi
IPC分类号： C07K16/28
CPC分类号： C07K16/2803 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61N5/02 , A61N5/0613 , A61N5/10 , A61N2005/0661 , A61N2005/1087 , A61N2005/1089 , C07K2317/24 , C07K2317/41 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2319/30 , G01N33/57492
摘要： The present invention relates to the anti-L1 monoclonal antibody 9.3 as well as to related antibodies or binding molecules and well as to the uses thereof, especially in tumor treatment.
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公开(公告)号：EP1868499A1
公开(公告)日：2007-12-26
申请号：EP06724051.5
申请日：2006-04-05
发明人： REMMERT, Gregor , ECHNER, Gernot
IPC分类号： A61B5/113
CPC分类号： A61B5/1135 , A61B5/055 , A61B5/7285 , A61B17/1322 , A61B2562/0266 , A61N5/1064
摘要： The invention relates to a respiratory belt system for being used in a magnetic resonance imaging environment. This system comprises a belt being elastically extendable, an optical transducer and an optical pattern being coupled to the belt. During extension or contraction of the belt the optical pattern is moved relative to the light source for a distance that is substantially identical to the length of the extension or the contraction of the belt. The sensor creates a measurement signal corresponding to the change in length of the belt.
摘要翻译： 本发明涉及用于磁共振成像环境中的呼吸带系统。 该系统包括可弹性延伸的带，光学换能器和耦合到带的光学图案。 在带的延伸或收缩期间，光学图案相对于光源移动一段距离，该距离基本上与带的延伸或收缩的长度相同。 传感器创建一个对应于皮带长度变化的测量信号。
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4.发明公开ASSEMBLY OF ABSOLUTELY QUANTIFIED PEPTIDE AND PHOSPHOPEPTIDE SOLUTIONS VIA ELEMENT MASS SPECTROMETRY 审中-公开施工ABSOLUTELY量化肽和PHOSPHOPEPTIDLÖSUNGEN关于元素质量
公开(公告)号：EP2387719A1
公开(公告)日：2011-11-23
申请号：EP10700844.3
申请日：2010-01-11
发明人： LEHMANN, Wolf-Dieter , ZINN, Nico , HAHN, Bettina
IPC分类号： G01N33/68
CPC分类号： G01N33/6848 , G01N33/6842 , G01N2333/916
摘要： The present invention relates generally to the fields of analytics of proteins and peptides. More particularly, the invention concerns generation of an absolutely quantified reference peptide or protein solution via element mass spectrometry. Furthermore, the invention relates to the absolute quantification of phosphopeptides and peptides by the use of an absolutely quantified peptide solution.
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5.发明公开DIAGNOSTIC TRANSCRIPT AND SPLICE PATTERNS OF HPV16 IN DIFFERENT CERVICAL LESIONS 有权DIAGNOSETRANSKRIPT-以及不同的颈部受伤HPV16剪接
公开(公告)号：EP2352845A1
公开(公告)日：2011-08-10
申请号：EP09748784.7
申请日：2009-11-09
IPC分类号： C12Q1/68
CPC分类号： C12Q1/708 , C12Q2545/113
摘要： The present invention relates to a method for differentiating in a subject with HPV 16 between (i) a severe form of HPV16 infection and (ii) a mild form of HPV16 infection based on determining the amount of a first gene product and a second gene product in a sample of a subject and calculating a ratio of the amount of said first gene product and the amount of said second gene product. Further envisaged by the present invention is a composition comprising an oligonucleotide mixture. Also envisaged by the present invention are a kit and a device adapted to carry out the method of the present invention.
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6.发明公开A method for lung cancer early detection and prognosis 审中-公开Verfahren zurFrüherkennungund Prognows von Lungenkrebs
公开(公告)号：EP2145964A1
公开(公告)日：2010-01-20
申请号：EP08160649.3
申请日：2008-07-17
发明人： Zander, Thomas , Schultze, Joachim L. , Wolf, Jürgen , Staratschek-Jox, Andrea , Debey-Pascher, Svenja , Eggle, Daniela , Boffetta, Paolo , Linseisen, Jakob
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/112 , C12Q2600/158
摘要： The present invention provides method for the prognosis or detection of lung cancer, notably for early detection of lung cancer, as well as a kit and a (micro) array suitable for said method.
摘要翻译： 本发明提供肺癌的预后或检测方法，特别是用于肺癌的早期检测，以及适用于所述方法的试剂盒和（微）阵列。
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公开(公告)号：EP2080039A2
公开(公告)日：2009-07-22
申请号：EP07821475.6
申请日：2007-10-17
发明人： PETER, Jörg
IPC分类号： G01T1/29
CPC分类号： G01T1/2985 , A61B6/037 , G01T1/1615
摘要： The invention relates to a triple-modality imaging system, wherein an optical imaging detector for acquiring optical tomography imaging data, a single photon emission computered tomography (SPECT) detector for acquiring SPECT data, and an x-ray source and detector for acquiring x-ray data are arranged to acquire optical imaging data, SPECT data, and x-ray data of an imaged object simultaneously, the optical imaging detector, the SPECT detector, and the x-ray detector having spatially over-lapping fields-of-view (FOV).
摘要翻译： 本发明涉及一种三模式成像系统，其中用于采集光学断层摄影成像数据的光学成像检测器，用于采集SPECT数据的单光子发射计算机断层摄影（SPECT）检测器以及用于采集x射线图像的x射线源和检测器， X射线数据被布置为同时获取成像对象的光学成像数据，SPECT数据和X射线数据，光学成像检测器，SPECT检测器和X射线检测器具有空间重叠的视场（ FOV）。
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8.发明授权
公开(公告)号：EP0785998B1
公开(公告)日：1998-07-29
申请号：EP94930172.5
申请日：1994-10-14
申请人： FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS (FO.R.T.H.) INSTITUTE OF MOLECULAR BIOLOGY & BIOTECHNOLOGY , DKFZ DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTS
CPC分类号： C12N15/113 , A61K38/00 , C12N2310/111 , C12N2310/121
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9.发明授权DIAGNOSTIC TRANSCRIPT AND SPLICE PATTERNS OF HPV16 IN DIFFERENT CERVICAL LESIONS 有权DIAGNOSETRANSKRIPT- UND SPLEISSMUSTER VON HPV16 BEI VERSCHIEDENEN HALSVERLETZUNGEN
公开(公告)号：EP2352845B1
公开(公告)日：2017-03-01
申请号：EP09748784.7
申请日：2009-11-09
IPC分类号： C12Q1/68
CPC分类号： C12Q1/708 , C12Q2545/113
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10.发明授权COMPOSITION COMPRISING AN OLIGONUCLEOTIDE MIXTURE FOR THE DETECTION OF CONTAMINATIONS IN CELL CULTURES 有权组合物包含寡核苷酸的混合物FOR在细胞培养物的认识 - 污染
公开(公告)号：EP2262908B1
公开(公告)日：2016-05-11
申请号：EP09717728.1
申请日：2009-03-05
发明人： SCHMITT, Markus , PAWLITA, Michael
IPC分类号： C12Q1/68
CPC分类号： C12Q1/689 , C12Q1/686 , C12Q1/6881 , C12Q1/701 , C12Q1/702 , C12Q1/705 , C12Q2600/16
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