摘要:
Apparatus for forming a single or a plurality of threedimensional optical traps, the apparatus comprising: a. A collimated light source that is directed onto an array of focalizing refractive or diffractive elements providing a single or a plurality of focal areas, and b. An array of reflective elements, placed opposite to the said focalizing elements described in a), which reflect back the light into the said focal area. The invention also relates to a method for using this apparatus.
摘要:
A device for transporting magnetic or magnetisable microbeads (25) in a capillary chamber (14) comprises a permanent magnet (10) or an electromagnet (11) for subjecting the capillary chamber to a substantially uniform magnetic field, to apply a permanent magnetic moment to the microbeads (25). At least one planar coil (22) and preferably an array of overlapping coils are located adjacent to the capillary chamber (14) for applying a complementary magnetic field on the microbeads parallel or antiparallel to said substantially uniform magnetic field, to drive the microbeads. An arrangement is provided for switching the current applied to the coil(s) (22) to invert the field produced thereby, to selectively apply an attractive or repulsive driving force on the microbeads (25). The device is usable to transport microbeads for performing chemical and biochemical reactions or assay, as is done for instance in clinical chemistry assays for medical diagnostic purposes.
摘要:
The present invention provides novel protein named Api m 6. Api m 6 was identified in bee venom and is found in four isoforms, each about 8 kD. The purified Api m 6 can be used to modulate immune responses, e.g., in individuals hypersensitive to bee venom.
摘要:
Microfluidic system comprising a space for containing a liquid and at least one lateral chamber in communication with said space, said lateral chamber containing a metal electrode. The lateral chamber and the space are designed to be filled by the same or different liquid when the system is active.
摘要:
An apparatus for retaining magnetic particles in self-assembled magnetic particle structures in a liquid flow, comprises a micro-channel (5) and magnets (1,2) for generating a substantially static magnetic field across the micro-channel (5) such that magnetic particles (12) suspended in a liquid in the micro-channel (5) form magnetic particle structures (15). The micro-channel (5) has along its length transverse large sections (8) alternating with narrow sections (9). The large sections (8) are periodically distributed along and on either side of the narrow sections (9) so that in use magnetic particle structures (15) form across the large sections (8) of the micro-channel (5), the magnetic particle structures being retained by engagement of end parts (18) of the magnetic particle structures in the large sections (8) of the cell or channel (5). The apparatus is useful in particular in life science, chemistry and microfiltration applications by flowing through the micro-channel (5) a fluid carrying molecules or particles to be captured, filtered or activated by the magnetic structures (15).
摘要:
Device for the in vitro culture of cells comprising :
a planar deformable substrate (3) with a culture surface (4), substrate deforming means for modifying the size of said culture surface (4), characterized by the fact that it furthermore comprises : substrate holding elements (5) which are located near the periphery of said culture surface (4), a frame (6,8) surrounding and directly or indirectly fixing said substrate holding elements (5), in such a way as to allow microscope viewing of the culture surface (4) and to avoid mechanical parts directly above or below the culture surface (4), said frame (6,8) being adapted to move said substrate holding elements (5) away from the center of said culture surface (4).
摘要:
Apparatus for forming a single or a plurality of threedimensional optical traps, the apparatus comprising: a. A collimated light source that is directed onto an array of focalizing refractive or diffractive elements providing a single or a plurality of focal areas, and b. An array of reflective elements, placed opposite to the said focalizing elements described in a), which reflect back the light into the said focal area. The invention also relates to a method for using this apparatus.
摘要:
A device for transporting magnetic or magnetisable microbeads (25) in a capillary chamber (14) comprises a permanent magnet (10) or an electromagnet (11) for subjecting the capillary chamber to a substantially uniform magnetic field, to apply a permanent magnetic moment to the microbeads (25). At least one planar coil (22) and preferably an array of overlapping coils are located adjacent to the capillary chamber (14) for applying a complementary magnetic field on the microbeads parallel or antiparallel to said substantially uniform magnetic field, to drive the microbeads. An arrangement is provided for switching the current applied to the coil(s) (22) to invert the field produced thereby, to selectively apply an attractive or repulsive driving force on the microbeads (25). The device is usable to transport microbeads for performing chemical and biochemical reactions or assay, as is done for instance in clinical chemistry assays for medical diagnostic purposes.